Proteomics
Scientists explore SARS-CoV-2 main protease as a drug target
A team of researchers report the structure of the main protease of the novel coronavirus and have identified several drugs that show promise in combating the virus, according to an April 9 article published in Nature.  Discuss
COVID-19 shuts down research labs as concern grows among scientists
Almost half of all scientific research labs that participated in a recent survey were shut down due to concerns about the COVID-19 outbreak. Survey results indicate that scientists are quite concerned and that their work is considerably impacted by the pandemic, according to a new COVID-19 scientist sentiment tracker.  Discuss
SARS-CoV-2 vaccine utilizing microneedle arrays appears in the literature
Within four weeks of the SARS-CoV-2 spike sequence becoming available, researchers from the University of Pittsburgh School of Medicine developed immunogens for a potential COVID-19 vaccine. The vaccine is delivered through a fingertip-sized patch, and it produces antibodies specific to SARS-CoV-2 at quantities thought to be sufficient for neutralizing the virus, according to the April 2 EBioMedicine publication.  Discuss
Horseshoe crab 'farming' preserves species, makes blood test possible
Researchers have developed a new aquaculture-based method to harvest immune cells from horseshoe crabs that preserves the crustaceans while also creating the potential for new clinical applications, like testing blood for sepsis, according to a study published in Frontiers in Marine Science on April 1.  Discuss
Extracellular RNA identifies new Alzheimer's biomarker
The association of extracellular RNA with upregulation of the phosphoglycerate dehydrogenase gene may be a useful presymptomatic biomarker for Alzheimer's disease, according to an article published in Current Biology on March 26.  Discuss
Scientists use bioinformatics to investigate origin of SARS-CoV-2
While many scientists urgently work toward developing successful therapies to fight the COVID-19 pandemic, some are looking in the opposite direction: to where SARS-CoV-2 came from. A new report published in the Journal of Proteome Research suggests that while bats are a likely natural reservoir, an intermediate host is probable.  Discuss
Scientists alter cell function with genetic engineering, polymer science
A new method called genetically targeted chemical assembly (GTCA) has demonstrated the ability to build artificial structures within the body to carry out unique functions. The research, presented in the latest edition of Science, provides compelling evidence for GTCA's ability to modify cell function with bioengineering tools.  Discuss
Systems-based analysis helps researchers understand cell migration
An international team of researchers has developed a unique library to study the regulation of the cytoskeleton in space and time. The work, published in Nature Cell Biology on March 23, takes a systems-based approach to gain an overview of this process.  Discuss
Cryo-EM sheds light on ion channel regulation
A long-standing hypothesis about the regulation of ion channels has been confirmed by cryoelectron microscopy (cryo-EM) imaging. The research presented in Nature on March 18 advances the basic understanding of key cellular processes that can be leveraged for a number of therapeutic and research applications.  Discuss
Shortage of RNA extraction kits threatens coronavirus testing
The weak link in the U.S. response to diagnostic testing for the novel coronavirus SARS-CoV-2 could be a shortage of RNA extraction kits. Fortunately, suppliers of RNA purification kits are working overtime to get more kits into circulation, according to Alice Kan of Strategic Directions International.  Discuss
Conferences
BioProcess International Europe
July 13-17
Central European Time Zone (CET) Netherlands
2020 ACCP Annual Meeting
September 20-22
Bethesda, Maryland United States
Bioprocess International West
September 21-24
Eastern Standard Time Zone (EST) United States
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Conferences
BioProcess International Europe
July 13-17
Central European Time Zone (CET) Netherlands
2020 ACCP Annual Meeting
September 20-22
Bethesda, Maryland United States
Bioprocess International West
September 21-24
Eastern Standard Time Zone (EST) United States
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