Multiomics analysis reveals potential opportunity for early intervention in Alzheimer’s
A gene that carries a strong risk for Alzheimer’s disease drives changes in the brain’s blood vessels that lead to problems in synapses and ultimately cognitive dysfunction, according to a study in mice. Read More
Imaging technique reveals previously unseen nanostructures in brain tissue
Swellable hydrogels have enabled researchers to “decrowd” biomolecular structures in cells and tissues, revealing previously hidden nanostructures and providing imaging of the structure of Alzheimer’s-linked amyloid beta plaques in greater detail than has been possible before. Read More
Blocking key enzyme boosts anticancer T-cell responses, resistance to immunosuppression
Blocking a key enzyme boosts anticancer T-cell responses and resistance to immunosuppression, according to a mice study from LSU Health New Orleans published August 26 in Frontiers in Immunology. Read More
Harvard’s Wyss Institute spins out protein detection technology to create Spear Bio
The Wyss Institute for Biologically Inspired Engineering at Harvard University has licensed technology for detecting proteins in small patient samples to a newly formed startup. Read More
Nanoparticles protect mice from blood vessel rupture, offers potential therapy for abdominal aortic aneurysms in humans
Administration of small interfering RNA nanoparticles has protected mice from sudden death due to the rupture of a major blood vessel in the abdomen, setting the stage for research that could ultimately enable treatment for people at risk of life-threatening abdominal aortic aneurysm. Read More
NIH team creates 3D structure of twinkle protein, sheds light on mitochondrial diseases
Researchers from the National Institutes of Health (NIH) have used cryo-electron microscopy and other techniques to create a 3D structure of the twinkle protein, the final piece of the human minimal mitochondrial replisome to be structurally characterized. Read More
First full map of immune system connections unlocks drug discovery opportunities
Researchers have created the first full map of immune system connections showing how immune cells communicate, pointing to ways to modulate the pathways to treat cancer and infectious diseases. Read More
Technology restores cell, organ function in pigs an hour after their deaths
Yale University scientists were able to restore blood circulation and other cellular functions in pigs a full hour after their deaths from cardiac arrest by using technology that delivers a specially designed cell-protective fluid to organs and tissues, according to a paper published August 3 in the journal Nature. Read More
Google’s DeepMind, Chan Zuckerberg Biohub hail separate AI-scientific breakthroughs
DeepMind and the European Molecular Biology Laboratory-European Bioinformatics Institute have used artificial intelligence (AI) to predict the 3D structures of nearly all cataloged proteins, while a team of Chan Zuckerberg Biohub scientists has developed a machine-learning method to quantitatively analyze and compare microscopy images of proteins with no prior knowledge. Read More
Video from AACC: Fluxergy's multimodal testing platform
Fluxergy president and co-founder Tej Patel sat down with us at AACC 2022 and discussed the company’s multimodal, multiomic platform that enables doctors to perform different kinds of tests, including reverse transcription polymerase chain reaction and serology tests, using a single instrument and software program. Read More
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