Proteomics
Metabolic control of Tregs is critical for immune tolerance
A new study identifies how metabolism exerts control over regulatory T (Treg) cells, which play a key role in the recognition of foreign and self-produced molecules. The findings, published in Cell Metabolism on November 17, may help scientists identify new drug targets for autoimmune diseases and cancers.  Discuss
Why are children more resistant to SARS-CoV-2 infection?
Why do children seem to be more resistant to SARS-CoV-2 infection than adults? The answer may lie in the age-dependent presence of a key viral enzyme, transmembrane protease serine 2, according to a new study published in the Journal of Clinical Investigation on November 12.  Discuss
Different immune response helps kids clear SARS-CoV-2 quickly
Why does the SARS-CoV-2 virus seem to have less of an impact on children than adults? A new study published November 5 in Nature Immunology investigates this question, finding that the immune systems of children respond differently to SARS-CoV-2 in a way that allows them to more easily clear the virus from their bodies.  Discuss
Proteomic changes in cancer cells provide new drug insights
Large-scale profiling of protein changes in response to drug treatment in cancer cell lines has been demonstrated as a powerful tool to predict drug sensitivity, understand drug resistance, and identify optimal drug combinations. The analysis was published in Cancer Cell on November 5.  Discuss
Synthetic nanobodies show potential for new COVID-19 therapies
Synthetic nanobodies may provide a practical avenue for the development of novel COVID-19 therapies compared to human antibodies, which are bulkier and require greater research investment. A study on synthetic nanobodies was conducted by a group of German researchers and published in Nature Communications on November 4.  Discuss
Most antibody responses to SARS-CoV-2 are strong and long-lasting
How long does the immune response last in patients with the SARS-CoV-2 virus? This has been a key question in shaping the public health response to the COVID-19 pandemic, and a new report published in Science on October 28 offers some good news.  Discuss
Can SARS-CoV antibodies be used to develop universal coronavirus vaccines?
Can antibodies developed against SARS-CoV during the 2003 outbreak be used to prevent infection by SARS-CoV-2? In an October 9 study published in Science Advances, researchers analyzed precious serum collected from convalescent SARS-CoV patients to find out.  Discuss
Long-lasting IgG antibodies found in blood and saliva of COVID-19 patients
Researchers have discovered that immunoglobulin G (IgG) antibodies to the SARS-CoV-2 virus are longer lasting in the blood and saliva of COVID-19 patients compared to the relatively short-lived IgM and IgA responses. The finding, presented in a pair of studies published in Science Immunology on October 8, suggests that IgG antibodies could be a promising target to detect and evaluate immune responses to the virus.  Discuss
Early trials show potential of Pfizer COVID-19 vaccine
Pharmaceutical giant Pfizer is making progress on BNT162b1, a COVID-19 vaccine candidate that is undergoing development and for which the U.S. government has secured access to 300 million doses in 2021. The results of the phase I/II clinical trials were published in Nature on August 12.  Discuss
Can agtech infrastructure be redeployed for pandemic preparedness?
Marshalling research equipment and expertise of the world's agricultural technology (agtech) laboratories could protect against future pandemics or epidemics, according to a new article published in Nature Biotechnology.  Discuss
Conferences
Festival of Genomics & Biodata
January 28-29, 2021
London, Greater London United Kingdom
Lab of the Future USA
May 11-12, 2021
Boston, Massachusetts United States
Conferences
Festival of Genomics & Biodata
January 28-29, 2021
London, Greater London United Kingdom
Lab of the Future USA
May 11-12, 2021
Boston, Massachusetts United States
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