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Help inform tools and technologies that advance research, treatments, and cures. The Science Advisory Board is an exclusive, online community that connects scientiﬁc and medical professionals across the world.

The Science Advisory Board is an exclusive, online community that connects scientific and medical professionals across the world.

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UK Scientists Weigh In on Brexit and Laboratory Spending - Science Advisory Board Insights
The long road to a resolution of the Brexit situation appeared to be nearing an end earlier this year, with the deadline set for March 29 to finalize how Britain would exit the EU. A “hard” Brexit, the case if no EU-Britain agreement is reached, would remove Britain from the EU’s single market among other consequences. A “soft” exit would result in Britain remaining part of the single market, but not an EU member. With a government stalemate in Britain, the EU agreed to extend the deadline until October 31, though a deal may come sooner. Discuss

Bioprocess Innovation: Why not?
The Science Advisory Board ® is excited to present the third piece in our trends in bioprocessing series, written by Angelo DePalma, Ph.D. This article discusses why innovations occur at such a slow pace in bioprocessing and drug development despite the rate of technological and scientific advancements. Discuss

Tech Overview: Quadrupole LC/MS
This week The Science Advisory Board will begin our Mass Spectrometry series. A mass spectrometer (MS), known as a mass spec, is an instrument that can measure the mass of different molecules within a sample. The mass spec can take a chemical compound and convert it from a molecule into ions. These ions are then separated according to their mass to charge ratio, and finally the abundance of each ion is measured. There are numerous types of MS systems, but all have six major components: the inlet system, ionization system, a vacuum system, mass analyzer, ion detector and a data handling system. Discuss

The Promise of Targeted Therapeutics in Cancer Treatment
In 2018, the International Agency for Research on Cancer reported more than 18 million people were diagnosed with cancer. Between 40 and 45 million people worldwide are living with cancer and nearly 9.6 million people die. Cancer deaths occur in about 50% of people who develop cancer in developed countries; this is in contrast to 80% death rate in cancer patients in underdeveloped countries. The numbers are staggering. But there is hope, as scientists around the globe work on developing new technologies, in the form of targeted therapies, to combat the incidence of cancer. Discuss

Trends in Bioprocessing: Continuous Upstream Bioprocessing
The Science Advisory Board ® is excited to present the second piece in our trends in bioprocessing series, written by Angelo DePalma, Ph.D. This article addresses the topic of continuous manufacturing, which is being extensively explored in academia and industry as a means to increase efficiency and integrate new technologies to bioprocessing operations.

Tech Overview: X-Ray Fluorescence Spectroscopy
The focus of today's atomic spectroscopy series will be X-ray fluorescence spectroscopy, known as XRF. XRF provides analysis of the atomic composition of samples for a wide variety of applications. The technique is particularly well suited for analyzing the elemental range from sodium to uranium, covering the majority of the metallic elements. XRF can be adjusted in order to detect lighter elements. Many samples can be effectively examined non-destructively, though others will require grinding, fusion, or some other form of sample preparation, in order to ensure that the measurement reflects the bulk properties of the sample rather than the surface. Discuss

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