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Science and scientists held in high esteem across the globe
September 29, 2020 -- An international survey conducted by the Pew Research Center found that scientists and their research are widely viewed in a positive light across global publics and many believe that government investments in research benefit society.  Discuss
Specialized T cells have unique role in severe COVID-19 cases
September 29, 2020 -- An unconventional subset of T cells may be strongly activated in patients with severe cases of COVID-19, according to a new study published in Science Immunology on September 28. This finding may lead to a new understanding of how the immune system responds to SARS-CoV-2 infection.  Discuss
COVID-19 concerns may undermine vaccine rates for seasonal flu
September 28, 2020 -- Only a third of parents believe that the flu vaccine will be more important this year, and 1 in 7 parents will not vaccinate their child due to concerns about COVID-19, according to the results of a new poll. The poll results underscore concerns that there could be a double impact of seasonal flu and COVID-19 this winter.  Discuss
Passive vaccines with mAbs may be effective for COVID-19
September 28, 2020 -- Monoclonal antibodies (mAbs) isolated from the blood of recovered COVID-19 patients -- known colloquially as "convalescent plasma" -- could be potentially useful as therapeutic and prophylactic agents for passive vaccination, assuming their administration does not trigger unwanted side effects. The findings of the new study were published in Cell on September 26.  Discuss
Is 'bespoke' therapy the future of genomic medicine?
September 25, 2020 -- Gene therapies hold extremely exciting promise for meeting the unmet needs of many individuals suffering from genetic diseases, as discussed in a session of the second annual American Society for Gene & Cell Therapy (ASGCT) Policy Summit on September 24.  Discuss
Science serves society, a crucial concept for gene therapy governance
September 24, 2020 -- With a focus on science and society, the American Society of Gene & Cell Therapy Policy Summit commenced on September 24. The ensuing discussion revealed how far science has advanced in a short period of time, and how the scientific community is rising to the challenge of gaining public buy-in for gene therapy.  Discuss
Are people in your state getting vaccinated?
September 24, 2020 -- Support for a COVID-19 vaccine continues to wane even as companies report being closer to bringing one to the public. This may not be surprising, considering people in many U.S. states don't get inoculated for other diseases such as polio and the flu.  Discuss
SARS-CoV-2 transcriptional patterns provide new insights into infection
September 23, 2020 -- New web resources provide insights into cellular genes that are impacted by coronavirus infection in the context of host molecular signaling pathways. These insights have the potential to speed novel drug development efforts in the fight against COVID-19, according to a new paper published in Scientific Data on September 22.  Discuss
New in vitro models reveal importance of lung stem cells in SARS-CoV-2 infection
September 22, 2020 -- Researchers have developed a new 2D lung organoid in vitro model as a physiologically relevant platform to aid drug development and explore the pathogenesis of SARS-CoV-2 infection. Details were published online in Cell Stem Cell on September 18.  Discuss
Analysis of COVID-19 literature identifies possible knowledge gaps
September 21, 2020 -- An analysis of COVID-19 scientific abstracts using natural language processing and machine-learning techniques suggests that the literature currently lacks basic research on the pathogenesis and viral transmission of SARS-CoV-2, according to a September 16 article published in Patterns.  Discuss
Structural changes of SARS-CoV-2 spike protein facilitate infection
September 21, 2020 -- The SARS-CoV-2 spike protein can adopt at least 10 sequential structural conformations when in contact with the human angiotensin-converting enzyme 2 receptor, according to a study conducted by researchers from the Francis Crick Institute and published in Nature on September 17.  Discuss
Celebration of postdocs transitions to virtual platform
September 18, 2020 -- For the first time ever, the National Postdoctoral Association will celebrate National Postdoc Appreciation Week from September 21-25 as a virtual, collaborative event among multiple institutions. Executive Director Tom Kimbis discusses how the organization is adapting to meet the challenges of COVID-19 to support and advocate for postdocs.  Discuss
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