PerkinElmer offers analysis platform for cell and gene therapy research, manufacturing
September 28, 2022 -- At the BioProcess International conference in Boston, PerkinElmer launched its new Cellaca PLX Image Cytometry System, which combines image cytometer hardware, software, validated consumables, and trackable data reporting -- all in one platform. Read More
Demand for viral vectors seen outpacing capacity growth despite investment surge
September 19, 2022 -- The growth in demand for viral vectors is outpacing a push to add capacity, leading to predictions that the current supply shortage will continue despite investment in the space. Read More
Link between circadian disruption and cancer may have to do with temperature: study
September 28, 2022 -- Scientists from the Scripps Research Institute have discovered a surprising link between circadian disruption and cancer that may have to do with temperature. Read More
Pew’s 2022 class of Innovation Fund Investigators to tackle biology, disease research
September 28, 2022 -- The Pew Charitable Trusts has announced Pew’s 2022 class of Innovation Fund Investigators. The researchers will look to advance scientific discovery and improve human health using their expertise. Read More
Gene editing possible for inherited retinal diseases
September 26, 2022 -- Precision genome editing agents can enable gene correction and disease rescue in inherited retinal diseases, according to University of California, Irvine researchers. Read More
Federal funding of $2B to support biotechnology and biomanufacturing
September 14, 2022 -- The White House announced on Wednesday federal funding of more than $2 billion to advance President Joe Biden’s executive order intended to enable the U.S. to harness the full potential of biotechnology and biomanufacturing. Read More
Study of antibiotic-caused hearing loss identifies potential therapeutic targets
September 27, 2022 -- Indiana University School of Medicine researchers used mouse laboratory models to study how aminoglycoside antibiotics may cause human hair cell death and permanent hearing loss, and in the process have identified potential therapeutic targets. Read More
2023 Breakthrough Prize winners in life sciences announced
September 26, 2022 -- Winners of the 2023 Breakthrough Prizes have been announced, including “game-changing” discoveries in the life sciences. Read More
SARS-CoV-2 mimics could make COVID-19 vaccine research safer, quicker
September 21, 2022 -- Viruslike particles, molecular mimics that look and act like SARS-CoV-2 without being infectious, are providing new tools against COVID-19 -- the disease caused by the virus. Read More
Mount Sinai scientists unlock secrets of key SARS-CoV-2 enzyme
September 12, 2022 -- Mount Sinai researchers have produced a high-resolution crystal structure of an enzyme that is essential to the survival of SARS-CoV-2. The finding could lead to more antivirals to combat current and future coronaviruses, they added. Read More
Swiss researchers awaken dormant cells to fight melanoma
September 23, 2022 -- Researchers from the University of Geneva and the University Hospitals of Geneva have identified a drug-targetable mechanism whose blockage reduces metastatic melanoma cells’ resistance to treatment. Read More
Heart medication spironolactone may also treat alcohol use disorder
September 21, 2022 -- Spironolactone, a diuretic medication used for heart problems and high blood pressure, may also effectively treat alcohol use disorder by reducing consumption, according to a new study published September 20 in the journal Molecular Psychiatry. Read More
NIH launches $42.5M program to investigate every human gene
September 28, 2022 -- The National Institutes of Health (NIH) is launching a $42.5 million program to systematically investigate every gene’s function and to catalog the consequences of inactivating each of those genes. Read More
Scientists unlock the secrets of gut coil development
September 26, 2022 -- Scientists now have a better understanding of embryo gut development: They've learned the counterclockwise gut rotation that occurs when the organ is formed is orchestrated by two waves of the transcription factor Pitx2 Read More
Scientists identify immune cell targets to fight chemo-resistant breast cancer
September 27, 2022 -- London-based scientists have identified certain immune cells that may potentially be targeted to develop immunotherapies that benefit patients with chemotherapy-resistant breast cancers. Read More
Researchers learn why carp virus inhibits host cell immune system
September 26, 2022 -- Belgian researchers have learned how a carp virus uses the protein domain Zalpha (Zα) to inhibit the defense mechanisms of the host cell. The discovery has implications for how Zα domain-containing proteins of the immune system function. Read More
Boosting TERRA levels damages DNA of hard-to-kill cancer cells: study
September 20, 2022 -- Increasing levels of telomeric repeat-containing RNA (TERRA) damages the DNA of cancers with a particular form of replicative immortality and leads to cell death, according to Portuguese researchers who show that “anti-aging clocks” can be used to kill cancer cells. Read More
Scientists pinpoint why alveolar macrophages don’t develop properly
September 19, 2022 -- Researchers in Germany have solved the mystery of what prevents alveolar macrophages from developing properly: the transcription factor CCAAT/enhancer binding protein beta (C/EBPβ). Read More
Researchers identify transcription factors that restore hearing in zebrafish
September 15, 2022 -- Certain transcription factors were able to restore hearing in zebrafish through cell regeneration and could inform treatments for hearing loss in humans, according to National Institutes of Health researchers. Read More
Single-cell sequencing reveals spatial map of immune cells in early-stage lung cancer
September 14, 2022 -- Using single-cell sequencing, researchers at the University of Texas MD Anderson Cancer Center have revealed a spatial map of tumor-infiltrating B cells and plasma cells that are prevalent in early-stage lung cancers, providing a basis for finding new immunotherapy targets. Read More
Science In Brief
Conferences
BioProcess International (BPI) Conference
September 27-30
Boston, Massachusetts United States
September 27-30
Boston, Massachusetts United States
Laboratory Products Association Annual Meeting
October 1-4
Scottsdale, Arizona United States
October 1-4
Scottsdale, Arizona United States
Cell & Gene Meeting on the Mesa
October 11-13
Carlsbad, California United States
October 11-13
Carlsbad, California United States
American Association of Pharmaceutical Scientists PharmSci 360 Annual Meeting
October 16-19
Boston, Massachusetts United States
October 16-19
Boston, Massachusetts United States
IDWeek 2022
October 19-23
District of Columbia United States
October 19-23
District of Columbia United States
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