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Early engagement with regulatory agencies is key to therapeutic development
October 20, 2021 -- Next-generation advanced therapies call for novel regulatory approaches, according to Mark Lane, PhD, vice president, development consulting and scientific affairs, of Biopharma Excellence by PharmaLex. Lane moderated a panel discussion titled "Innovative Regulatory Pathways for Next-Generation Treatments" at the 2021 Cell & Gene Meeting on the Mesa. Read More
New platform identifies best viral vectors for gene therapy
October 20, 2021 -- Researchers have developed a novel computational platform that identifies the best viral vector to deliver a gene therapy to its target. The technology, described October 19 in eLife, promises to speed development of adeno-associated virus-mediated gene therapies against vision loss and other disorders. Read More
Bacteria use 'belt and braces' defense system vs. bacteriophages
October 19, 2021 -- Researchers have shown how a plasmid in the bacterium Escherichia fergusonii uses a "belt and braces" approach to defend itself against bacteriophages. The breakthrough, published on October 18 in Nucleic Acids Research, could lead to new DNA-targeting biotechnology tools. Read More
Cardiovascular cell, gene therapy leaders discuss nascent field
October 18, 2021 -- The emerging field of cardiovascular cell and gene therapies shows great promise to significantly improve clinical outcomes, but it still faces key challenges, according to an October 13 plenary session at the Cell & Gene Meeting on the Mesa. Read More
CGTBO editor comments on trends from Cell & Gene Meeting on the Mesa
October 18, 2021 -- Blake Middleton, editor of Cell & Gene Therapy Business Outlook (CGTBO), was joined by Bruce Carlson, senior vice president of publications at Science and Medicine Group, to review the latest developments in therapies from the 2021 Cell  & Gene Meeting on Mesa. Read More
Machine Bio crowned as BioTools Innovator champion
October 15, 2021 -- CARLSBAD, CA - Machine Bio co-founder and CEO David Marash delivered an impassioned pitch that resulted in the protein synthesis company being named the inaugural winner of the BioTools Innovator Competition. Read More
Opportunities abound in cell and gene therapy for discerning investors
October 14, 2021 -- CARLSBAD, CA - There are more opportunities in the cell and gene therapy sector than ever before. But to profit from them, investors must be more discerning than in the past, according to a panel of investors at the Cell & Gene Meeting on the Mesa on October 14. Read More
Precision Advance aims to improve patient access to cell and gene therapy
October 14, 2021 -- Improving patient access to cell and gene therapy treatments is the goal of Precision Advance, an initiative of Precision Medicine Group. Precision Advance provides a set of interconnected services and personnel designed to help bring new therapies to market. Read More
Dialogue with regulators will help bring cell and gene therapies to market
October 13, 2021 -- CARLSBAD, CA - Open engagement and frequent communication with regulators is needed throughout the development process for cell and gene therapies to help bring them to market, according to an October 13 session at the Cell & Gene Meeting on the Mesa. Read More
Catching up with the Alliance for Regenerative Medicine at Cell & Gene Meeting on the Mesa
October 13, 2021 -- CARLSBAD, CA - What's going on at this week's Cell & Gene Meeting on the Mesa? ScienceBoard.net spoke with Stephen Majors, director of public affairs at the Alliance for Regenerative Medicine, who shared what's being discussed at this year's meeting. Read More
What's next for cellular immunotherapies?
October 13, 2021 -- CARLSBAD, CA - What's the next step in the development of cellular immunotherapies, particularly for liquid and solid tumors? At this week's Cell & Gene Meeting on the Mesa, Dr. Kanya Rajangam, PhD, of Nkarta Therapeutics explained the latest approaches. Read More
New algorithm enables comparisons of tumors across patients
October 12, 2021 -- Researchers have developed an algorithm that can take either single-cell mass cytometry data or RNA sequencing data, align it, and extract a common denominator for comparing cancer data among patients. The algorithm, called tuMap, was detailed in a study published on October 7 in Cell Systems. Read More
Tecartus becomes 1st CAR T-cell therapy to receive FDA approval for adults with ALL
October 11, 2021 -- Tecartus (brexucabtagene autoleucel), a CAR T-cell therapy, has gained approval from the U.S. Food and Drug Administration (FDA) for the treatment of relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL) in adult patients. Read More
GenSight Biologics to highlight gene therapies at Cell & Gene Meeting
October 11, 2021 -- French biotechnology firm GenSight Biologics is highlighting its lenadogene neparvovec (Lumevoq) and GS030 gene therapies at the Cell & Gene Meeting on the Mesa in Carlsbad, CA. Read More
Scientists create atlas of mouse brain regions down to single cells
October 8, 2021 -- An atlas of the mouse cerebrum and primary motor cortex down to the level of single cells was published in a pair of papers on October 6 in Nature. The research reveals the mammalian brain's organization at an unprecedented level of detail and sheds new light on gene regulatory factors, promising to inform future work on developing targeted therapies for human diseases. Read More
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