New energy-generation methods could enable creation of entirely new organisms
March 29, 2023 -- Developing biologically realistic energy-generation methods that mimic natural processes could pave the way for the creation of entirely new organisms or biomaterials, according to a study published on Tuesday in Biophysics Reviews. Read More
Beckman Coulter, Sciex collaborate on high-throughput screening workflows
February 27, 2023 -- Life science analytical technologies company Sciex on Monday announced a collaboration with Beckman Coulter Life Sciences to provide comprehensive workflows for high-throughput screening; high-throughput absorption, distribution, metabolism, and excretion (HT-ADME); and synthetic biology studies. Read More
Driver of responses to checkpoint inhibitors suggests way to improve cancer therapy
March 29, 2023 -- Expansion of a diverse subset of T-cell clones influences how patients respond to immune checkpoint inhibitors (ICIs), suggesting it may be possible to predict who will benefit from the treatments. Read More
Getting to the root of Alzheimer’s disease
March 29, 2023 -- More than 40 experts and 13 institutions are collaborating on a five-year, $41 million study funded by the National Institutes of Health (NIH) National Institute on Aging aimed at better understanding the biological pathways underlying Alzheimer’s disease. Read More
A*STAR partners with startup to create diabetes cell therapies tailored to Asian patients
March 22, 2023 -- BetaLife has acquired the rights to human induced pluripotent stem cell (iPSC) technology from Singapore’s Agency for Science, Technology, and Research (A*STAR) for use in the treatment of diabetes. Read More
CRISPR/Cas9 mouse model reveals cellular function changes that drive rare disease
March 21, 2023 -- A CRISPR/Cas9 mouse model has shown how mutations that cause a rare disease affect cellular function, shedding light on how to monitor and treat the condition in the process. Read More
New insights into an old drug: Aspirin
March 29, 2023 -- Recent discoveries about how aspirin works to reduce inflammation could lead to alternative medications with fewer side effects. The National Institutes of Health (NIH)-funded research was presented on Tuesday at the annual meeting of the American Society for Biochemistry and Molecular Biology, held March 25-28 in Seattle. Read More
Thermo Fisher Scientific opens cell therapy facility at University of California, San Francisco
March 27, 2023 -- Thermo Fisher Scientific and the University of California, San Francisco (UCSF) said Monday that they will develop cell therapies for difficult-to-treat conditions, including cancers, rare diseases, and other illnesses. Read More
Pandemic played out in vastly different ways across the U.S.: Study
March 24, 2023 -- A comprehensive state-by-state analysis of COVID-19 impacts across the U.S. revealed the underlying forces driving wide variations in health, education, and economic performance. Read More
Rapid nirmatrelvir treatment may reduce long COVID risk
March 24, 2023 -- A study of people with SARS-CoV-2 infection who had at least one risk factor for progression to severe disease found that treatment with nirmatrelvir within five days of a positive SARS-CoV-2 test result was associated with reduced risk of post−COVID-19 condition, known as long COVID. The findings, published Thursday in JAMA Internal Medicine, held true across the risk spectrum in this cohort, regardless of vaccination status and history of prior infection. Read More
SomaLogic CEO steps down; Q4 revenue declines 18%
March 31, 2023 -- Aptamer-based proteomics firm SomaLogic said after the close of the market on Tuesday that its fourth-quarter revenue declined 18% year over year, primarily due to the recognition of $1.9 million of licensing revenue in the fourth quarter of 2021. Read More
RNA-seq analysis links protein to spread of pancreatic cancer, reveals potential drug target
March 23, 2023 -- An analysis of 400 pancreatic cancer tumor samples has linked a protein that controls RNA processing to the formation of metastases, suggesting that it may be possible to delay the spread of the cancer. Read More
What to do when genetic tests reveal links to cardiovascular disease: Scientific statement
March 27, 2023 -- Increased use of genetic testing means that people may discover they have an incidentally-found genetic abnormality, or gene variant, associated with cardiovascular disease (CVD), according to a scientific statement published Monday in the American Heart Association journal Circulation: Genomic and Precision Medicine. Read More
Shared genetic markers linked with substance use disorders
March 24, 2023 -- By combing through genomic data from more than one million people, scientists have identified genes commonly inherited across addiction disorders, regardless of the substance being used. Read More
Implication of nervous system in anaphylaxis opens ways to treat severe allergic reactions
March 20, 2023 -- Heat-sensing neurons are key contributors to severe allergic shock reactions, according to a study in mice that points to ways to reverse life-threatening symptoms. Read More
Nasal antibody modulates inflammatory response in COVID-19 patients in small clinical trial
March 9, 2023 -- A nasally administered monoclonal antibody modulated inflammatory responses in COVID-19 patients in a small clinical trial. Read More
Correlation of enzyme to survival reveals potential target for metastatic solid tumors
March 10, 2023 -- The enzyme lysyl hydroxylase 1 (LH1) promotes the migration and metastasis of solid tumor cells and is associated with shorter survival, according to a recent study published in Molecular Cancer. Read More
At SLAS 2023, BioAuxilium Research announces expansion of TR-FRET technology portfolio
March 1, 2023 -- BioAuxilium Research this week announced the expansion of its no-wash Thunder time-resolved Förster resonance energy transfer (TR-FRET) technology portfolio at the annual Society for Laboratory Automation and Screening (SLAS) International Conference and Exhibition in San Diego. Read More
Scientists create cell atlas of developing human lung
December 9, 2022 -- Researchers from the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute, the Gordone Institute at the University of Cambridge, and collaborators have created a spatiotemporal cell atlas of the developing human lung. From the mapping, they have identified 144 cell states in the early stages of life and their interactions in new detail. Read More
Senescent neuron discovery in brains opens path for Alzheimer's drug development
December 2, 2022 -- Scientists at the Salk Institute for Biological Studies have found that neurons from people with Alzheimer's disease show deterioration and undergo a late-life stress process called cellular senescence, while senescent cells could be a way to slow neuroinflammation and neurodegeneration. Read More
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