Beckman Coulter, Sciex collaborate on high-throughput screening workflows February 27, 2023 -- Life science analytical technologies company Sciex on Monday announced a collaboration with Beckman Coulter Life Sciences to provide comprehensive workflows for high-throughput screening; high-throughput absorption, distribution, metabolism, and excretion (HT-ADME); and synthetic biology studies.Read More
Stem cell therapy targets brain metastatic melanomas May 31, 2023 -- Twin stem cells acting in unison may activate the immune system to suppress metastatic melanoma tumor growth in the brain, according to Department of Defense-funded research, published Wednesday in Science Translational Medicine. The procedure prolonged survival in preclinical trials on mice, indicating that locally delivered immunotherapies may be beneficial in brain metastases treatment.Read More
Chemical compound stimulates nerve regeneration, protects heart tissue May 24, 2023 -- Researchers have identified a compound that can stimulate nerve regeneration after injury, as well as protect cardiac tissue from the type of damage seen in heart attacks. The study, published Wednesday in Nature, identified a chemical compound called 1938, which activates the signaling pathway of phosphoinositide 3-kinase (PI3K), an enzyme that helps control cell growth.Read More
Foundation Medicine enters companion diagnostic collaboration with Merck KGaA June 8, 2023 -- Foundation Medicine said Monday that it has entered a strategic collaboration with Merck KGaA in Darmstadt, Germany to develop FoundationOne Liquid CDx and FoundationOne CDx as companion diagnostics in the U.S. market for selected marketed and pipeline treatments.Read More
Nucleai, Mayo Clinic partner on digital pathology June 8, 2023 -- Nucleai and Mayo Clinic BioPharma Diagnostics on Monday announced a strategic collaboration involving digital pathology solutions, technologies, and services to support drug development and clinical practice.Read More
Researchers identify genomic variants for rare genetic skin disorder June 2, 2023 -- Researchers used genome sequencing to identify the genomic variants that cause disabling pansclerotic morphea, a rare and serious inflammatory skin disorder. The results, published Wednesday in the New England Journal of Medicine, may point the way to a treatment, the researchers said.Read More
Scientists create cell atlas of developing human lung December 9, 2022 -- Researchers from the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute, the Gordone Institute at the University of Cambridge, and collaborators have created a spatiotemporal cell atlas of the developing human lung. From the mapping, they have identified 144 cell states in the early stages of life and their interactions in new detail.Read More
Senescent neuron discovery in brains opens path for Alzheimer's drug development December 2, 2022 -- Scientists at the Salk Institute for Biological Studies have found that neurons from people with Alzheimer's disease show deterioration and undergo a late-life stress process called cellular senescence, while senescent cells could be a way to slow neuroinflammation and neurodegeneration.Read More