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Bioengineered peptide combats antibiotic-resistant bacteria
December 7, 2021 -- Researchers have engineered a bioinspired molecule that was highly effective in clearing infections caused by antibiotic-resistant bacteria strains in a mouse model, according to a paper published in Scientific Reports on December 6. But there's a twist: The molecule doesn't act like an antibiotic. Read More
Aclaris Therapeutics publishes zunsemetinib preclinical research
December 6, 2021 -- Aclaris Therapeutics has published preclinical research of zunsemetinib in pancreatic cancer in the peer-reviewed journal Science Translational Medicine on December 1. Read More
Gamma delta T cells may hold key to malaria immunity
December 3, 2021 -- Scientists have shown how a poorly understood group of immune cells -- gamma delta T cells -- are directly involved in immunity to malaria, according to research published December 1 in Science Translational Medicine. The results promise to spur the future development of next-generation malaria vaccines. Read More
Decode Genetics publishes largest study of the plasma proteome
December 3, 2021 -- In a study published December 2 in Nature Genetics, scientists at Decode Genetics, a subsidiary of pharmaceutical company Amgen, demonstrated how measuring levels of several proteins in plasma at population scale combined with data on sequence diversity and RNA expression dramatically increases insights into human diseases and other phenotypes. Read More
New machine-learning approach promises to speed drug design
December 1, 2021 -- A new approach to machine learning outperformed current machine-learning methods in drug design, demonstrating its potential in speeding up the drug discovery process, according to research published online November 29 in the Proceedings of the National Academy of Sciences. Read More
BioTools Innovator opens 2022 applications
November 30, 2021 -- BioTools Innovator is now accepting applications from startups and emerging growth companies for its second annual accelerator program. The program aims to advance innovation in life science and improve human health by accelerating the growth of best-in-class startups that are developing and commercializing biotechnology products, platforms, and services. Read More
Machine-learning system decodes nuclear magnetic resonance spectra of organic crystals
November 30, 2021 -- A group of researchers has developed a machine-learning framework that assigns the chemical shifts of organic crystals directly from their 2D structure -- accelerating an often time-consuming process. The study was published November 26 in Science Advances. Read More
Sartorius grows operations in France
November 30, 2021 -- Sartorius is expanding its capacities for production, innovation, and storage in France by investing 100 million euros ($117 million) between 2021 and 2025. Read More
Istari moves quickly to validate its poliovirus vaccine-based cancer immunotherapy
November 29, 2021 -- It's been a busy year for Istari Oncology, which is developing its PVSRIPO viral immunotherapy based on the poliovirus vaccine. Istari's President and CEO Matt Stober and Chief Medical Officer Dr. Garrett Nichols recently spoke with ScienceBoard about the progress of PVSRIPO for the treatment of solid tumors. Read More
Researchers create artificial nanopores capable of detecting DNA
November 24, 2021 -- Scientists have designed bottom-up peptides that can form artificial nanopores to identify and enable single molecule-sorting of genetic material in a lipid membrane, according to new research published in Nature Nanotechnology on November 22. Read More
Stem cell model reveals gene expression during development of hypothalamus
November 23, 2021 -- Researchers created an in vitro stem cell model of the hypothalamus to study its development over different stages. In doing so, they identified several genes involved with bodily functions associated with the hypothalamus, including disorders related to sleep and reproduction, according to research published November 19 in Nature Communications. Read More
Asgard Therapeutics raises seed funding for novel in vivo cancer immunotherapy
November 22, 2021 -- Asgard Therapeutics, a private biotech startup based in Lund, Sweden, has raised 6 million euros (about $6.8 million) in seed financing, co-led by Novo Holdings, a global life science investor based in Hellerup, Denmark. Read More
Technology upgrades needed to address future pandemics, GAO report says
November 19, 2021 -- Vaccine R&D and manufacturing face many challenges despite the success of COVID-19 vaccines. This is according to a new U.S. Government Accountability Office (GAO) report. Read More
Myxoma virus enters as an exciting preclinical cancer immunotherapy platform
November 18, 2021 -- A preclinical oncolytic viral vector platform under development was of interest at the recent Society for Immunotherapy of Cancer's 2021 annual meeting. OncoMyx Therapeutics' Chief Scientific Officer Leslie Sharp, PhD, spoke with ScienceBoard at the meeting. Read More
5 takeaways from SITC 2021
November 17, 2021 -- WASHINGTON, DC - The Society for Immunotherapy of Cancer's (SITC) 2021 annual meeting November 10-14 was a successful gathering of research and clinical experts focused on the development of innovative cancer treatments. The ScienceBoard team was live onsite at the event. Editor in Chief Samantha Black, PhD, shared five takeaways from the meeting. Read More
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