New energy-generation methods could enable creation of entirely new organisms
March 29, 2023 -- Developing biologically realistic energy-generation methods that mimic natural processes could pave the way for the creation of entirely new organisms or biomaterials, according to a study published on Tuesday in Biophysics Reviews. Read More
Beckman Coulter, Sciex collaborate on high-throughput screening workflows
February 27, 2023 -- Life science analytical technologies company Sciex on Monday announced a collaboration with Beckman Coulter Life Sciences to provide comprehensive workflows for high-throughput screening; high-throughput absorption, distribution, metabolism, and excretion (HT-ADME); and synthetic biology studies. Read More
Burning Rock Biotech highlights breast cancer study using its genomic profiling test
June 8, 2023 -- Precision oncology firm Burning Rock Biotech on Thursday announced that its genomic profiling test, OncoScreen Plus, was used in a phase III multiregional breast cancer clinical trial, alongside Foundation Medicine's FoundationOneCDx. Read More
FDA updates recommendations to modernize design, conduct of clinical trials
June 7, 2023 -- The U.S. Food and Drug Administration (FDA) on Tuesday released a draft guidance document with updated recommendations for good clinical practices aimed at modernizing the design and conduct of clinical trials. Read More
BioCentriq, Kytopen expand partnership on cell therapy manufacturing technology
June 6, 2023 -- BioCentriq, a contract development and manufacturing organization specializing in cell therapy, and Kytopen, a Massachusetts Institute of Technology-based startup, on Tuesday announced that they are expanding their partnership. Read More
Stem cell therapy targets brain metastatic melanomas
May 31, 2023 -- Twin stem cells acting in unison may activate the immune system to suppress metastatic melanoma tumor growth in the brain, according to Department of Defense-funded research, published Wednesday in Science Translational Medicine. The procedure prolonged survival in preclinical trials on mice, indicating that locally delivered immunotherapies may be beneficial in brain metastases treatment. Read More
Visualization of key step in protein production points to potential antibiotic target
June 2, 2023 -- Single-particle cryo-electron microscopy (cryo-EM) has visualized a key step in the production of proteins by bacteria, generating insights that could inform the development of new antibiotics. Read More
Chemical compound stimulates nerve regeneration, protects heart tissue
May 24, 2023 -- Researchers have identified a compound that can stimulate nerve regeneration after injury, as well as protect cardiac tissue from the type of damage seen in heart attacks. The study, published Wednesday in Nature, identified a chemical compound called 1938, which activates the signaling pathway of phosphoinositide 3-kinase (PI3K), an enzyme that helps control cell growth. Read More
Long COVID symptoms reported by 17% of unvaccinated people
June 1, 2023 -- Swiss researchers have found that about 17% of unvaccinated people report experiencing COVID-19-related health problems up to two years after SARS-CoV-2 infection. Read More
Cryo-electron microscopy sheds light on key step in replication of SARS-CoV-2
May 31, 2023 -- Researchers have used cryo-electron microscopy (cryo-EM) to visualize a critical step in the replication of SARS-CoV-2, generating insights that could inform the development of COVID-19 drugs. Read More
Foundation Medicine enters companion diagnostic collaboration with Merck KGaA
June 8, 2023 -- Foundation Medicine said Monday that it has entered a strategic collaboration with Merck KGaA in Darmstadt, Germany to develop FoundationOne Liquid CDx and FoundationOne CDx as companion diagnostics in the U.S. market for selected marketed and pipeline treatments. Read More
Nucleai, Mayo Clinic partner on digital pathology
June 8, 2023 -- Nucleai and Mayo Clinic BioPharma Diagnostics on Monday announced a strategic collaboration involving digital pathology solutions, technologies, and services to support drug development and clinical practice. Read More
Thermo Fisher Scientific, Seer expand collaboration to broaden access to mass-spec proteomics
June 7, 2023 -- Life sciences proteomics firm Seer on Wednesday announced an expanded collaboration with Thermo Fisher Scientific. Read More
Researchers identify genomic variants for rare genetic skin disorder
June 2, 2023 -- Researchers used genome sequencing to identify the genomic variants that cause disabling pansclerotic morphea, a rare and serious inflammatory skin disorder. The results, published Wednesday in the New England Journal of Medicine, may point the way to a treatment, the researchers said. Read More
HIV nanoparticle vaccine induces strong T-cell responses in early-phase clinical trial
May 26, 2023 -- An HIV nanoparticle vaccine has induced strong T-cell responses in a first-in-human clinical trial, marking a step toward the development of a product that protects against the virus. Read More
Clinical trial begins for universal flu vaccine candidate
May 16, 2023 -- Researchers at NIH’s National Institute of Allergy and Infectious Diseases (NIAIDs) have developed an experimental universal influenza vaccine. Read More
Thermo Fisher Scientific introduces high-resolution, high-throughput mass spectrometer
June 5, 2023 -- Thermo Fisher Scientific on Monday introduced its Orbitrap Astral mass spectrometer, which combines high resolution, high throughput, and high speed with deep proteome coverage. Read More
Researchers map RNA to inform selection of stem cells for therapeutic applications
May 12, 2023 -- Creating maps of the RNA inside cells could improve cell therapies by enabling the isolation of subsets of cells with similar characteristics, according to a study published Friday in Cell Reports Methods. Read More
Scientists create cell atlas of developing human lung
December 9, 2022 -- Researchers from the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute, the Gordone Institute at the University of Cambridge, and collaborators have created a spatiotemporal cell atlas of the developing human lung. From the mapping, they have identified 144 cell states in the early stages of life and their interactions in new detail. Read More
Senescent neuron discovery in brains opens path for Alzheimer's drug development
December 2, 2022 -- Scientists at the Salk Institute for Biological Studies have found that neurons from people with Alzheimer's disease show deterioration and undergo a late-life stress process called cellular senescence, while senescent cells could be a way to slow neuroinflammation and neurodegeneration. Read More
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