Beckman Coulter, Sciex collaborate on high-throughput screening workflows February 27, 2023 -- Life science analytical technologies company Sciex on Monday announced a collaboration with Beckman Coulter Life Sciences to provide comprehensive workflows for high-throughput screening; high-throughput absorption, distribution, metabolism, and excretion (HT-ADME); and synthetic biology studies.Read More
Biomarkers in a study predict stem cell transplant risks May 23, 2023 -- Risk biomarkers uncovered in a recent study may help medical staff predict which donor stem cell transplant patients are likely to develop a potentially deadly side effect called sinusoidal obstruction syndrome (SOS).Read More
Chemical compound stimulates nerve regeneration, protects heart tissue May 24, 2023 -- Researchers have identified a compound that can stimulate nerve regeneration after injury, as well as protect cardiac tissue from the type of damage seen in heart attacks. The study, published Wednesday in Nature, identified a chemical compound called 1938, which activates the signaling pathway of phosphoinositide 3-kinase (PI3K), an enzyme that helps control cell growth.Read More
A closer look at long COVID symptoms May 10, 2023 -- Patients with persistent neurological symptoms after SARS-CoV-2 infections were intensively studied and found to have autonomic dysfunction and differences in their immune cell profiles. The findings, published last Friday in Neurology: Neuroimmunology & Neuroinflammation, may help explain lingering long-COVID neurological symptoms, and lead to better diagnoses and treatments.Read More
Targeting viral RNA to treat infection April 26, 2023 -- Despite the rapid development of COVID-19 vaccines, the rise of variants forces scientists to frequently modify treatments. A new study published Wednesday in ACS Central Science describes a treatment that directly targets and degrades the viral ribonucleic acid (RNA) genome, reducing SARS-CoV-2 infection in mice.Read More
Modified anti-nausea drug enters cells, treats pain May 22, 2023 -- Altering the chemical properties of the anti-nausea drug netupitant enables it to enter interior cell compartments and provide long-lasting pain relief, according to research published Monday in the Proceedings of the National Academy of Sciences (PNAS).Read More
DNA Script announces broad launch of DNA printing platform May 22, 2023 -- DNA Script on Monday announced the broad commercial availability of the fully automated Syntax DNA printing platform, saying that it consists of the benchtop STX-200 system, advances in biochemistry, robust reagent kits, and intuitive software enhancements.Read More
Scientists create cell atlas of developing human lung December 9, 2022 -- Researchers from the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute, the Gordone Institute at the University of Cambridge, and collaborators have created a spatiotemporal cell atlas of the developing human lung. From the mapping, they have identified 144 cell states in the early stages of life and their interactions in new detail.Read More
Senescent neuron discovery in brains opens path for Alzheimer's drug development December 2, 2022 -- Scientists at the Salk Institute for Biological Studies have found that neurons from people with Alzheimer's disease show deterioration and undergo a late-life stress process called cellular senescence, while senescent cells could be a way to slow neuroinflammation and neurodegeneration.Read More