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Scientists see through human organs for the first time
February 14, 2020 -- For the first time, scientists have made human organs transparent with the use of a new imaging technique called SHANEL, which stands for small-micelle-mediated human organ efficient clearing and labeling. The details were published in Cell on February 13.  Discuss
Genetically engineered probiotics successfully deliver immunotherapies
February 13, 2020 -- A new technology enables genetically engineered probiotic bacteria to be used as an efficacious, stable, and safe platform to deliver immunotherapies directly into a variety of tumors in just a single dose. The research was published online on February 12 in Science Translational Medicine.  Discuss
Phages containing huge amounts of DNA are found around the globe
February 12, 2020 -- An inventory of over 350 DNA sequences from phage genomes revealed that these genomes can be over 200,000 base pairs in length and found the largest phage genome ever described at 735,000 base pairs in length. The report published in Nature on February 12, evaluated the prevalence, diversity and ecosystem distribution of phages with large genomes.  Discuss
T cells work as a team to fight infection
February 11, 2020 -- Immune cells may be better at sensing each other than previously thought, according to a new study published in Immunity on February 11. Researchers from Germany, the Netherlands, and the U.K. revealed a mechanism T cells use to work as a team and mutually determine how to fight infections.  Discuss
CRISPR proteins developed for use in molecular diagnostics
February 11, 2020 -- New CRISPR technology is being developed as a molecular diagnostic tool with the capability of detecting unique disease biomarkers. Eventually, these at-home tests will allow patients to conduct at-home diagnostic tests quickly.  Discuss
Could a plant virus help create a new MRI contrast agent?
February 10, 2020 -- What's old is new for University of Texas at Dallas researchers who are resurrecting an organic, biodegradable compound that someday might be the foundation for a nongadolinium-based magnetic resonance imaging (MRI) contrast agent, according to a preclinical study published online on February 5 in Chemical Science.  Discuss
3D model of human intestines helps simulate leaky gut condition
February 10, 2020 -- Researchers are using 3D models of human intestines to simulate leaky gut conditions -- in which microbes and molecules seep out of the intestines, eliciting an immune response. The research, published in Life Science Alliance on February 10, will help identify biomarkers for leaky gut for improved diagnostics and treatment development.  Discuss
Experts map the future of bioprinting
February 7, 2020 -- Bioprinting has rapidly advanced in both techniques and clinical applications, but key challenges still remain for the burgeoning field. A multinational team of researchers offered their recommendations for how to address these hurdles in an in-depth road map article published February 7 in Biofabrication.  Discuss
Genomics sheds light on the life history of cancers
February 6, 2020 -- As part of a special collection of papers on pan-cancer analysis of whole genomes published online by Nature on February 6, an international group of scientists analyzed over 2,500 unique cancer genomes to shed light on the life history of cancer mutations and how cancer tumors evolve -- even before they are diagnosed.  Discuss
New fluorescence technique builds more vivid views
February 5, 2020 -- A novel imaging technique improves processing time of hyperspectral fluorescence imaging and allows scientists to peer more deeply and clearly into living organisms. Researchers from the University of Southern California Michelson Center for Convergent Bioscience have been developing the technology for years and have published their findings in Nature Communications on February 5.  Discuss
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