Proteomics
Microscopy with fluorescent tags gives high-def view of diabetes-related proteins
Leveraging the power of new imaging techniques, scientists are using unique fluorescent tags in combination with superresolution microscopy to gain novel insights into a receptor that plays a key role in controlling blood sugar levels. These insights will open the door to improved treatment options for type 2 diabetes.  Discuss
New study offers hope for short-circuiting KRAS-driven lung cancers
The protein kinase p38α has been identified as a key element supporting KRAS-driven lung cancers, so inhibiting the protein has potential as a target for the treatment of certain lung cancers. An international group of researchers used genetic mouse models with the KRAS mutation to observe how p38α inhibition reduces tumor growth. The work was published in the Proceedings of the National Academy of Sciences on January 22.  Discuss
Small-molecule chaperones may reverse Alzheimer's symptoms in mice
A novel treatment for Alzheimer's disease involving the administration of pharmacological chaperones that prevent amyloid beta and tau tangles from forming in the brain may be possible, according to a new study published online on January 22 in Molecular Neurodegeneration.  Discuss
Scientists in the Lab: Featuring Rajan Chaudhari
We are thrilled to introduce our next laboratory scientist this month, who works at the intersection of chemistry, drug development, and data science. Rajan Chaudhari, PhD, is a postdoctoral fellow at the University of Texas MD Anderson Cancer Center in Houston.  Discuss
Scientists learn how lactate contributes to cancer formation
Previously considered a waste product of metabolism, lactate may play a crucial role in cancer growth, according to a study published in Frontiers in Oncology on January 14. Researchers from the University of Colorado Anschutz Medical Campus explored how lactate affects transcription of oncogenes in breast cancer cells.  Discuss
Scientists in the Lab: Featuring Lisa Mustachio
Continuing our feature series this January, ScienceBoard is happy to highlight the work of laboratory scientists, including Lisa Maria Mustachio, PhD, a postdoctoral fellow at MD Anderson Cancer Center.  Discuss
Dietary probiotics show potential to reverse Parkinson's symptoms
Roundworms that were fed a commercially available dietary probiotic showed less buildup of proteins that form during the progression of Parkinson's disease in a new study, published in Cell Reports on January 14. The finding provides further evidence of a link between the gut microbiome and brain function.  Discuss
Control of molecular 'doormen' in fat cells offers potential new obesity treatment
New treatment options for obesity could emerge from a study published in Nature Communications on January 10. Researchers from Yale University School of Medicine utilized cellular and molecular approaches to identify pathways to restore the healthy balance of fat cells.  Discuss
Bacterial evolution reveals method to fight antibacterial resistance
Different types of bacteria have evolved to develop unique mechanisms for achieving the same antibacterial function -- a finding that could lead to new ways to combat antibacterial resistance, according to scientists from Trinity College Dublin. They tested their findings using methicillin-resistant Staphylococcus aureus in a study that was published in Nature Communications on January 9.  Discuss
Scientists in the Lab: Featuring Rebecca Fleeman
This month, ScienceBoard is featuring scientists in the laboratory to celebrate their important contributions to the scientific community. We are excited to introduce our first featured scientist of this month, Rebecca Fleeman of Penn State College of Medicine in Hershey, PA.  Discuss
Conferences
BioProcess International Europe
July 13-17
Central European Time Zone (CET) Netherlands
2020 ACCP Annual Meeting
September 20-22
Bethesda, Maryland United States
Bioprocess International West
September 21-24
Eastern Standard Time Zone (EST) United States
General Discussion
Topic Replies / Views Last Update
https://academic.oup.com/ve/pages/coronavirus-evolution
by Michael
0 / 47 More than 3 days ago
by Michael
PopSci Hails Impossible Burger 2.0 as Most Important Engineering Innovation in 2019
by Mahesh Gupta
0 / 14 More than 3 days ago
by Mahesh Gupta
Engineered Bacteria Produces BeeFree Honey
by Mahesh Gupta
0 / 12 More than 3 days ago
by Mahesh Gupta
Consumers' Preference to Buy Unlabeled Produce Increases after Exposure to GMO-labeled Pro
by Mahesh Gupta
0 / 15 More than 3 days ago
by Mahesh Gupta
Super-precise new CRISPR tool could tackle a plethora of genetic diseases
by Mahesh Gupta
0 / 14 More than 3 days ago
by Mahesh Gupta
To see more posts from our community or to share a post of your own, go to our community's forum page.
Conferences
BioProcess International Europe
July 13-17
Central European Time Zone (CET) Netherlands
2020 ACCP Annual Meeting
September 20-22
Bethesda, Maryland United States
Bioprocess International West
September 21-24
Eastern Standard Time Zone (EST) United States
Connect
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter