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Scientists develop new bacterial tool to improve, speed drug manufacturing
July 8, 2022 -- A new bacterial tool developed by scientists at the University of Texas at Austin has the potential to improve and speed up the drug manufacturing process, according to an article published on July 7 in Nature Chemical Biology. Read More
FDA approves Teva Pharmaceuticals’ CU method
July 7, 2022 -- The U.S. Food and Drug Administration (FDA) approved a content uniformity (CU) method from Teva Pharmaceuticals that uses the Agilent TRS100 Raman quantitative pharmaceutical analysis system. Read More
FDA approves first topical gene therapy for treatment of wounds in patients with dystrophic epidermolysis bullosa
May 19, 2023 -- The U.S. Food and Drug Administration (FDA) said on Friday it has approved Vyjuvek, a herpes-simplex virus type 1 (HSV-1) vector-based gene therapy, for the treatment of wounds in patients six months of age and older with dystrophic epidermolysis bullosa (DEB) and with mutations in the collagen type VII alpha 1 chain (COL7A1) gene. Read More
Revvity, AstraZeneca ink license agreement for next-gen base editing tech
May 19, 2023 -- Revvity this week announced a nonexclusive license agreement with AstraZeneca for the technology underlying a next-generation modular gene editing platform. Read More
Cell & Gene Meeting on the Mesa 2022 Recap
November 9, 2022 -- The Science and Medicine Group team was onsite at this year's Cell & Gene Meeting on the Mesa getting the who, what, and when on the product announcements, science sessions, and deals taking place this year. Find out what we learned in our recap. Read More
Gene therapy targets overactive brain cells in mice, potential neurological treatment
November 4, 2022 -- University College London researchers have developed a gene therapy for neurological and psychiatric diseases that reduces the excitability of overactive brain cells. Tested in mice, the scientists contend the treatment could potentially be used in human brain diseases caused by excessive activity of a small number of brain cells. Read More
MIT researchers record cellular memories through protein chains
January 4, 2023 -- Using engineered proteins, MIT researchers have designed a system in which they can record “memories” of sequences of cellular events, such as when certain genes are activated, or how cells respond to a drug, as cells turn on series of genes and pathways in performing functions. Read More
Boosting RNA therapies to create natural pacemakers
December 20, 2022 -- Smidt Heart Institute scientists have investigated how biological pacemaker cells fight back against RNA therapies to correct abnormal heartbeat rates. Read More
Short-lived nasal antibodies against COVID-19 may explain reinfection
December 20, 2022 -- Research led by the University of Liverpool and Imperial College London found that antibodies produced in the nose decline nine months after COVID-19 infection, while antibodies in the blood last at least a year. Read More
Plant offers potential for massive scale production of COVID-19 tests, vaccines
December 19, 2022 -- Viral antigen-based diagnostic tests as well as various vaccines have been key tools in fighting COVID-19. Read More
Researchers find new target for drug-resistant ovarian cancer
April 17, 2023 -- Researchers working in a preclinical study have verified a new target for recurrent drug-resistant ovarian cancer and provided data to support a treatment approach now in clinical trials. The findings were presented on Sunday, during the American Association for Cancer Research (AACR) 2023 annual meeting. Read More
Chemists construct largest ligand-enclosed nanocage to expand drug delivery options
April 7, 2023 -- The creation of what its developers believe to be the largest ever ligand-enclosed nanocage has increased the carrying capacity and expanded the utility of drug delivery vehicles. Read More
Cellecta releases NGS assays for T-cell and B-cell receptor chains
April 12, 2023 -- Genomics company Cellecta announced on Wednesday that it has launched its DriverMap Adaptive Immune Receptor DNA (AIR-DNA) TCR and BCR kits that provide rapid, single-tube polymerase chain reaction (PCR) analysis of the variability of T-cell and B-cell receptor chains from a range of sample types, including tissue biopsy, whole blood, purified immune cells, and others. Read More
Genetically engineered probiotic keeps mice sober, protects liver after alcohol exposure
April 11, 2023 -- A genetically engineered probiotic has accelerated recovery from alcohol exposure in mice, suggesting the approach could mitigate hangovers and adverse outcomes associated with excessive consumption. Read More
CRISPR-Cas9 gene editing links RNA-binding protein to immunotherapy resistance
November 21, 2022 -- Using CRISPR-Cas9 gene editing, Swiss researchers have provided evidence that expression of an RNA-binding protein helps tumors to evade the immune system. Read More
Cancer cell biology suggests which patients will respond to immunotherapy
November 18, 2022 -- Researchers have discovered that more genetic material on chromosome 9 in cancer cells translates into a three times longer survival rate than those patients without it for certain kinds of head and neck cancer. Read More
New antibody neutralizes all known SARS-CoV-2 variants: study
August 12, 2022 -- An antibody developed at Boston Children’s Hospital neutralizes all known SARS-CoV-2 variants, including omicron subvariants, which may inform the design of future COVID-19 vaccines. Read More
Nanoparticles protect mice from blood vessel rupture, offers potential therapy for abdominal aortic aneurysms in humans
August 11, 2022 -- Administration of small interfering RNA nanoparticles has protected mice from sudden death due to the rupture of a major blood vessel in the abdomen, setting the stage for research that could ultimately enable treatment for people at risk of life-threatening abdominal aortic aneurysm. Read More
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