Cell Biology
Berkeley Lab offers CRAGE kit for genome engineering
Lawrence Berkeley National Laboratory (Berkeley Lab) is offering a trial kit for its chassis-independent, recombinase-assisted, genome engineering (CRAGE) tool. Read More
LabCentral Ignite receives $400K grant to improve diversity in STEM
LabCentral Ignite has been awarded $400,000 in grants and matching awards from the U.S. Economic Development Administration and Breakthrough Properties, a life science real estate development company, to expand its Career Forge program. The nonprofit also announced that it is accepting applicants for its next Career Forge session. Read More
USCAP 2022: 4 tips for a more sustainable lab
LOS ANGELES -- The global biotechnology and pharmaceutical industry has a carbon footprint greater than even the forestry or paper industry, but there are ways scientists can help decrease their environmental impact, according to a keynote lecture at this week's United States and Canadian Academy of Pathology (USCAP) 2022 meeting. Read More
Cellular map of tissues created by combining sequencing techniques
Researchers have described an approach to combine single-cell sequencing experiments with spatial transcriptomics to create maps of tissues according to cell type, according to new research published on March 21 in the journal Nature Biotechnology. Read More
Organizations invest in stem cell research using unique approaches
Stem cell technology is increasingly being used and developed for a variety of therapeutic purposes, most notably for the treatment of damaged tissue. While these treatments have significant clinical potential, they also require extensive research and investment to support the development of these novel therapies. Read More
Endosomal pH drives stemness in glioblastoma
A group of researchers has shown that endosomal pH drives stemness in glioblastoma. The group discovered that endosomal Na+/H+ exchanger isoform 9 is a novel driver of stem cell-like characteristics -- or stemness -- in glioblastoma by stabilizing multiple receptor tyrosine kinases, according to a recent paper published in PNAS Nexus. Read More
'Roadmap' reveals how cells transform during mouse embryonic development
Mapping how complex animals develop from a single cell is a key area of study, but it remains a significant challenge. Now, research published in Nature Genetics on March 14, has laid out the molecular changes that control how cells transform during mouse embryonic development. The resulting roadmap identifies potential links between cell types to help understand the paths they take toward specialization. Read More
New checkpoint target boosts immunotherapies against solid tumors in mice
The human immune system can be a powerful weapon in halting the spread of cancer, leading to long-term remission. However, many tumors find ways to protect themselves by switching off the immune response. Scientists have discovered a new way to reactivate T cells to attack solid tumors and boost existing therapies in mice, according to research published in Cancer Discovery on March 8. Read More
How diversity, inclusion help one company turn sci-fi into sci-fact
Juliana Blum, PhD, co-founder and executive vice president of corporate development at Humacyte, spoke with ScienceBoard about diversity and inclusion in the life sciences, especially about being a woman in science. Read More
Combined imaging approach gives detailed picture of blood vessels
Mapping out the intricate network of blood vessels in tissues can help researchers to better understand the changes in diseases like dementia or cancer. However, techniques to image the vasculature are individually limited and difficult to combine. Now, a new easy-to-use system, described in a paper published February 10 in the journal Nature Methods, can combine multiple imaging techniques to provide more detailed information at a range of scales. Read More
Conferences
International Society for Cell and Gene Therapy Annual Meeting
May 4 - June 7
San Francisco, California United States
Interphex 2022 Conference
May 24-26
New York, New York United States
American Society for Mass Spectrometry Annual Conference
June 5-9
Minneapolis, Minnesota United States
American Society for Microbiology Microbe Meeting
June 9-13
District of Columbia United States
HPLC 2022
June 18-23
San Diego, California United States
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