The Science Advisory Board

Cell culture Cell-based analysis Virology Bacteriology Microbiome

Researchers reveal vulnerabilities of 'addicted' cancer cells
New findings about the mechanism by which some cancer cells can become "addicted" to glucose could lead to fresh approaches to targeted cancer therapies. The results of the research were published in Nature Cell Biology on March 30. Discuss

Scientists use bioinformatics to investigate origin of SARS-CoV-2
While many scientists urgently work toward developing successful therapies to fight the COVID-19 pandemic, some are looking in the opposite direction: to where SARS-CoV-2 came from. A new report published in the Journal of Proteome Research suggests that while bats are a likely natural reservoir, an intermediate host is probable. Discuss

Controversy hits Gilead over orphan status for COVID-19 drug
Gilead Sciences has rescinded its request for orphan drug status for an experimental drug for treating COVID-19 just two days after getting approval from the U.S. Food and Drug Administration. The company had been hit with criticism that the approval would block other COVID-19 drugs from reaching the market. Discuss

Researchers explore mutations to improve drug design
Drug resistance is a common challenge when designing therapeutics for cancers or diseases originating from bacteria or viruses. Researchers explored how evolution impacted the mutation of these pathogens, and their findings could lead to the development of evolutionarily designed drugs. The results were published March 24 in Cell Reports. Discuss

Scientists alter cell function with genetic engineering, polymer science
A new method called genetically targeted chemical assembly (GTCA) has demonstrated the ability to build artificial structures within the body to carry out unique functions. The research, presented in the latest edition of Science, provides compelling evidence for GTCA's ability to modify cell function with bioengineering tools. Discuss

Systems-based analysis helps researchers understand cell migration
An international team of researchers has developed a unique library to study the regulation of the cytoskeleton in space and time. The work, published in Nature Cell Biology on March 23, takes a systems-based approach to gain an overview of this process. Discuss

Cryo-EM sheds light on ion channel regulation
A long-standing hypothesis about the regulation of ion channels has been confirmed by cryoelectron microscopy (cryo-EM) imaging. The research presented in Nature on March 18 advances the basic understanding of key cellular processes that can be leveraged for a number of therapeutic and research applications. Discuss

Comparative genomics confirms natural development of SARS-CoV-2
The available genetic data on SARS-CoV-2 indicate that it is not derived from any previously known virus, suggesting that it originated from either natural selection in an animal host or humans following zoonotic transfer. This analysis, presented in Nature Medicine on March 17, provides evidence for the natural evolution of this novel coronavirus amid claims of manufactured origins. Discuss

New lung cancer biomarker could significantly improve patient outcomes
A new protein has been identified on tumor-derived extracellular vesicles that indicates if a lung tumor is likely to metastasize, according to research published in Science Advances on March 11. A minimally invasive biomarker test to catch cancer early could significantly improve patient outcomes. Discuss

Gene amplification can be responsible for functional innovation in bacteria
Researchers have gained a greater understanding of how gene amplifications rapidly tune levels of gene expression when gene regulation is required but when no other molecular regulatory mechanisms are in place. This research was published in Nature Ecology & Evolution on March 9. Discuss

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Conferences

Microbiology Society Annual Conference 2020
March 30 - April 3
Edinburgh, Edinburgh, City of United Kingdom

Experimental Biology 2020
April 4
San Diego, California United States

BioProcess International Europe
April 28 - May 1
Amsterdam, Noord-Holland Netherlands

Lab of the Future USA
May 19-20
Boston, Massachusetts United States

2nd Annual Cell Therapy Bioprocessing Conference
June 25-26
Boston, Massachusetts United States

More Conferences »»

Topic	Replies / Views	Last Update
General Discussion

Open science for the modern scientific community by LMoraes	3 / 51	More than 3 days ago by The Mets
https://academic.oup.com/ve/pages/coronavirus-evolution by Michael	0 / 14	More than 3 days ago by Michael
PopSci Hails Impossible Burger 2.0 as Most Important Engineering Innovation in 2019 by Mahesh Gupta	0 / 8	More than 3 days ago by Mahesh Gupta
Engineered Bacteria Produces BeeFree Honey by Mahesh Gupta	0 / 11	More than 3 days ago by Mahesh Gupta
Consumers' Preference to Buy Unlabeled Produce Increases after Exposure to GMO-labeled Pro by Mahesh Gupta	0 / 14	More than 3 days ago by Mahesh Gupta
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