Machine learning used to encode commands for immune cells
December 9, 2022 -- Researchers at University of California San Francisco (UCSF), in collaboration with a team at IBM Research, have developed a virtual molecular library of thousands of “command sentences” for cells, based on combinations of “words” that guide engineered immune cells to seek out and kill cancer cells without pausing. Read More
Shenandoah expands cytokine, growth factors portfolio for cell and gene therapies
December 7, 2022 -- Shenandoah Biotechnology, a Fujifilm Irvine Scientific company, has announced the expansion of its CTGrade portfolio of cytokine and growth factors for cell and gene therapies that are manufactured following current good manufacturing practices. Read More
CIRM awards $8M for gene therapy research on rare, incurable diseases
December 2, 2022 -- The California Institute for Regenerative Medicine (CIRM) has awarded $8 million in grants for two research teams investigating gene therapy for rare and incurable diseases. Read More
Scientists uncover viral vectors that cross the blood-brain barrier
November 23, 2022 -- Using a "directed-evolution" strategy in mice and macaques, scientists at the Broad Institute of Massachusetts Institute of Technology and Harvard have identified adeno-associated viruses that cross the blood-brain barrier, advancing efforts to develop neurological disease gene therapies. Read More
PerkinElmer launches viral vector assays to boost gene therapy research
November 22, 2022 -- PerkinElmer has announced the launch of its "ready-to-use" adeno-associated virus vectors detection kits to support researchers working on gene therapies for a variety of diseases. Read More
Multiplexed 'CAR Pooling' accelerates evaluation of anticancer cell therapy receptors
November 14, 2022 -- Researchers have developed a new method for comparing massive numbers of CAR T cells, each with slightly different molecular features, to determine which is most effective and long-lasting against cancer. Read More
Cell & Gene Meeting on the Mesa 2022 Recap
November 9, 2022 -- The Science and Medicine Group team was onsite at this year's Cell & Gene Meeting on the Mesa getting the who, what, and when on the product announcements, science sessions, and deals taking place this year. Find out what we learned in our recap. Read More
Gene therapy targets overactive brain cells in mice, potential neurological treatment
November 4, 2022 -- University College London researchers have developed a gene therapy for neurological and psychiatric diseases that reduces the excitability of overactive brain cells. Tested in mice, the scientists contend the treatment could potentially be used in human brain diseases caused by excessive activity of a small number of brain cells. Read More
Academic CDMOs, like commercial ones, play critical role in CGT sector
October 27, 2022 -- The cell and gene therapy (CGT) industry is growing and academic contract development and manufacturing organizations (CDMOs) -- like their larger commercial counterparts -- are playing a critical role in the ecosystem, according to Stuart Curbishley, PhD, head of business and process development at the University of Birmingham’s Advanced Therapies Facility. Read More
Induced pluripotent stem cell technology offers potential treatment for hair loss
October 25, 2022 -- Science Advisory Board spoke with Stemson Therapeutics co-founder and CEO Geoff Hamilton earlier this month at the 2022 Cell & Gene Meeting on the Mesa about the preclinical stage cell therapy company's focus on curing hair loss by leveraging the regenerative power of induced pluripotent stem cells. Read More
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