Manufacturing partnerships support high quality cell therapies Chimeric Therapeutics, Ncardia, and Novartis are some of the companies that have decided to partner to make complex manufacturing processes more efficient for novel therapies, according to Cell and Gene Therapy Business Outlook, a sister publication of ScienceBoard.Read More
MASTER technology could transform CAR T-cell therapy A new technology that helps CAR T cells attack cancer cells more aggressively than conventional methods has been published by researchers from North Carolina. Called multifunctional alginate scaffold for T-cell engineering and release (MASTER), the technology was described in a paper published on March 24 in Nature Biotechnology.Read More
NKILT moves from stealth mode to active fundraising ScienceBoard.net recently caught up with NKILT Therapeutics leaders Raphael Ognar and Henri Bayle at the 2022 American Association for Cancer Research Annual Meeting in New Orleans.Read More
Tetanus immunity treats pancreatic cancer in mice Pancreatic cancer is difficult to treat, and patients have not benefited from the advances in immunotherapy seen in other diseases. Now, in new research, scientists have demonstrated how the childhood tetanus vaccine could be used to activate the immune system to fight against tumors, according to a study published recently in the journal Science Translational Medicine.Read More
Nivolumab/chemo combo will change lung cancer care A new study that pairs neoadjuvant nivolumab with chemotherapy for patients with nonsmall cell lung cancer has the potential to revolutionize treatment, according to one expert. The research was presented April 11 at the American Association for Cancer Research 2022 meeting and published simultaneously in the New England Journal of Medicine.Read More
CAR T-cells show preliminary efficacy, safety as solid-tumor treatment Researchers presented phase I/II preliminary clinical trial data demonstrating the safety and efficacy of a new CAR T-cell therapy that can be used as either a monotherapy or a combination therapy to treat Claudin 6-positive solid tumors. The findings were presented at the American Association for Cancer Research Annual Meeting 2022 in New Orleans.Read More
CRISPR technique may lead to hypoallergenic cats Love cats but have allergies? Rejoice! Scientists have demonstrated that CRISPR gene editing of the cat allergen, Felis domesticus allergen I, could bring relief to those with cat allergies, according to a proof-of-concept study published online in the CRISPR Journal.Read More
Gene therapy shows long-term benefits for children with WAS A lentiviral-based gene therapy treatment for children with Wiskott-Aldrich Syndrome (WAS) has demonstrated long-term benefits, according to research recently published in Nature Medicine. The findings demonstrate a safe alternative to the traditional treatment protocol.Read More
Advancing the development of biologics provides stronger clinical options A therapeutic area that is gaining traction is the field of biologics. Such therapies are highly useful in treating diseases because they can mimic and complement naturally occurring physiological processes in the human body that may be key to treating the dysfunction. As a result, biologics are frequently used to treat immune-mediated and inflammatory disease states.Read More
LabCentral Ignite receives $400K grant to improve diversity in STEM LabCentral Ignite has been awarded $400,000 in grants and matching awards from the U.S. Economic Development Administration and Breakthrough Properties, a life science real estate development company, to expand its Career Forge program. The nonprofit also announced that it is accepting applicants for its next Career Forge session.Read More