The Science Advisory Board

Biosimulation can mitigate risk of COVID-19 drug development
Drug development can be an expensive and tedious process. Add in the urgency of the COVID-19 pandemic, and you have a recipe for frustration. Biosimulation -- using computers to simulate drug response in humans -- can help accelerate the process, which Certara hopes to achieve with a new platform launched today targeted at COVID-19 vaccine development. Discuss

COVID-19 vaccine based on peptide nanofibers shows promise
A new technology platform using self-assembling peptide nanofibers tagged with antibodies can be an effective SARS-CoV-2 vaccine, according to a proof-of-concept study published in Science Advances on August 7. Discuss

Gum disease may affect COVID-19 severity
Patients with inflammation caused by periodontitis may experience more severe COVID-19 complications, according to an article published online July 30 in the Journal of the California Dental Association. Discuss

Microbes shape antibodies prior to infection
Genetic analysis of antibodies reveals how microbes in the intestines impact overall B-cell populations and humoral responses to pathogens. The research was published in Nature on August 5. Discuss

New COVID-19 vaccine candidate leverages earlier research
Could vaccine platforms developed for previous coronaviruses be converted to address the current COVID-19 pandemic? An August 5 report in Nature described how researchers leveraged previous vaccine research to develop mRNA-1273, a new SARS-CoV-2 vaccine candidate. Discuss

Study analyzes how SARS-CoV-2 undermines immune defenses
A new research study used whole-genome sequencing to analyze the genetic profile of patients with the SARS-CoV-2 virus to gain more insight into how it turns the body's own immune system against itself. The findings could help researchers develop drugs to target the virus, according to an August 3 report in Nature Medicine. Discuss

Researchers develop mouse model of COVID-19 infection
Researchers have generated a strain of SARS-CoV-2 that can infect mice and used it to produce a new mouse model of infection to help facilitate testing of COVID-19 vaccine candidates and therapies. The research article was published in Science on July 30. Discuss

Animal study turns in positive results for Moderna-NIH COVID-19 vaccine
Moderna's COVID-19 vaccine candidate, messenger RNA (mRNA)-1273, has been shown to induce immune responses and control upper and lower respiratory tract infection of rhesus macaques exposed to SARS-CoV-2, according to researchers from the U.S. National Institutes of Health's (NIH) National Institute of Allergy and Infectious Diseases. Discuss

Genetic regulation of immune diseases starts at birth
Areas of the human genome may explain the early origins of chronic immune and inflammatory diseases that develop later in life, according to a study published in Nature Communications on July 28. Discuss

New tools rapidly detect anti-SARS-CoV-2 antibodies
New tools using surrogate viruses may be useful for rapid testing to determine whether antibodies effectively neutralize SARS-CoV-2. The viral vector-based platform approach was published in the Journal of Experimental Medicine on July 21. Discuss

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Conferences

ACS Fall 2020 Virtual Meeting & Expo
August 17-20

ESMO Virtual Congress 2020
September 14-29

2020 ACCP Annual Meeting
September 20-22
Bethesda, Maryland United States

Bioprocess International West
September 21-24
Eastern Standard Time Zone (EST) United States

BioProcess International
September 21-24
Eastern Standard Time Zone (EST), Massachusetts United States

More Conferences »»

Topic	Replies / Views	Last Update
General Discussion

Childhood vaccines may help protect against COVID-19 mortality by Ratcatcher	0 / 6	More than 3 days ago by Ratcatcher
https://academic.oup.com/ve/pages/coronavirus-evolution by Michael	0 / 49	More than 3 days ago by Michael
PopSci Hails Impossible Burger 2.0 as Most Important Engineering Innovation in 2019 by Mahesh Gupta	0 / 14	More than 3 days ago by Mahesh Gupta
Engineered Bacteria Produces BeeFree Honey by Mahesh Gupta	0 / 13	More than 3 days ago by Mahesh Gupta
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