Drug Discovery & Development
Stanford team synthesizes anticancer compound currently only sourced from rainforest tree
The synthesis of an anticancer compound in the laboratory by Stanford University researchers has cleared a barrier to the widespread use of a drug candidate that is currently extracted from a single plant species. Read More
Computational screening uncovers potential painkillers without addictive, sedation properties
University of California, San Francisco researchers have used computational screening of 301 million virtual molecules to uncover non-opioid compounds that treated pain without causing sedation in animals, offering lead candidates as an alternative to narcotics. Read More
Biotech licenses drug discovery platform from Harvard, Tufts to study complex CNS diseases
Unravel Biosciences has licensed a drug discovery platform from Harvard University and Tufts University to decode and model complex central nervous system (CNS) diseases. Read More
MIT miniaturizes antenna for wireless operation inside living cells
Massachusetts Institute of Technology (MIT) researchers have created an antenna that can operate inside cells and is compatible with 3D biological systems, with the potential for applications in diagnostics and therapeutics. Read More
Machine learning may accelerate solutions to address protein design challenges
Machine learning can be used to create protein molecules much more accurately and quickly than previously possible, with the potential for developing new treatments and vaccines, according to biologists at the University of Washington School of Medicine. Read More
MIT team finds limitations of AlphaFold’s AI protein structures in drug discovery
Advances in the modeling of protein-ligand interactions are needed to realize the potential of the artificial intelligence (AI) AlphaFold database of protein structure predictions in drug discovery, according to a new paper from researchers at the Massachusetts Institute of Technology (MIT). Read More
Harvard’s Wyss Institute spins out protein detection technology to create Spear Bio
The Wyss Institute for Biologically Inspired Engineering at Harvard University has licensed technology for detecting proteins in small patient samples to a newly formed startup. Read More
Lupus pill moves to clinical trial in humans after success in mice
Scientists at this week’s fall meeting of the American Chemical Society report they have begun phase II clinical trials of an oral pill containing a compound that in mice, not only prevented lupus-like symptoms, but also reversed signs of organ damage caused by the disease and prevented death. Read More
Biomolecular condensates could transform drug discovery, says Dewpoint Therapeutics
Boston-based biotech company Dewpoint Therapeutics contends there are untapped opportunities for targeting biomolecular condensates to develop therapeutic agents for a wide array of diseases, potentially transforming the drug discovery process. Read More
Novel drug targets cancer cells in mice through lymphatic system, shows therapeutic efficacy
A novel kinase inhibitor, absorbed through the gut’s lymphatic system rather than blood vessels, significantly reduced disease, limited toxicity, and prolonged survival in mice with myelofibrosis, according to a University of Michigan study. Read More
Conferences
Cell & Gene Meeting on the Mesa
October 11-13
Carlsbad, California United States
American Association of Pharmaceutical Scientists PharmSci 360 Annual Meeting
October 16-19
Boston, Massachusetts United States
IDWeek 2022
October 19-23
District of Columbia United States
American Society of Human Genetics Annual Meeting
October 25-29
Los Angeles, California United States
International Society for Pharmaceutical Engineering Annual Meeting
October 30 - November 2
Orlando, Florida United States
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