Proteomics
Leveraging new technologies to push the boundaries of our knowledge of cell biology
At the American Society of Cell Biology, European Molecular Biology Organization Joint Meeting in Washington, DC from December 7-11, emerging topics and new technologies were discussed and highlighted. Proteomics and genomics seemed to be a focus of the meeting. Many researchers presented novel ideas to incorporate new technologies in these fields to make discoveries in cell biology.
New microscopy technique helps scientists understand cancer growth and spread
Researchers from Duke Cancer Institute have developed a new technique to observe stem cell mutations occurring in colon cancer.  Discuss
Algorithm detects unknown anomalies in RNA-seq data
A new computational approach to analyzing gene expression data is presented by computational biologists from Carnegie Mellon University (CMU) and published in Cell Systems on November 27.  Discuss
Data Science Vital to Large-Scale Cellular Studies
Data science as a discipline has become a central aspect of many commercial endeavors. A large range of distinct applications have adopted its approaches and techniques. Despite the major differences in many of these applications, some of the techniques can be transferred from old and established data-driven fields to new, completely separate data-intensive areas. For example, certain image analysis algorithms from astronomy can be applied in fields involving microscopy.  Discuss
New molecular drivers of Parkinson's disease identified
A group of researchers at the Icahn School of Medicine at Mount Sinai have discovered new molecular drivers of Parkinson's disease (PD) and subsequently determined how they impact the function of genes involved in the disease. This was accomplished using a complex statistical technique called multiscale gene network analysis (MGNA). The results were published in Nature Communications on November 20.  Discuss
Bacterial structures are critical to the development of new antibiotics
A research team from Cornell University have uncovered a unique regulatory mechanism unique to bacterial that may provide crucial insight for antibiotic targeting of pathogens. The work was published in Nature Structural & Molecular Biology on November 18.  Discuss
Is there a reproducibility problem with RNA-seq data?
Modern day technology has allowed scientists to analyze highly complex genomic data sets. However, with this comes increased challenges associated with reproducibility and misinterpretation of results from massive data sets. One such example, RNA sequencing (RNA-Seq), provides the ability to simultaneously measure gene expression levels of all genes in a sample in a single test.  Discuss
Novel enzyme structure discovered by scientists
A research team at the University of California, Riverside, has discovered the structure of a novel RNA-modifying enzyme and identified the mechanism that controls substrate specificity. The study was published in Nature Communications on November 6 and explains how protein machinery in cells is regulated to target RNA molecules for modification.
Novel strategy for studying mitoribosomal and mitochondrial impact on disease
Researchers from the Karolinska Institutet in Sweden have developed a new experimental tool for studying mitochondrial protein synthesis in vivo. This research is presented in the October 5 issue of Cell Reports.  Discuss
Immune cells shown to kill MRSA before it enters the body
Neutrophils could be responsible for controlling bacterial numbers of an antibiotic-resistant strain of Staphylococcus aureus (MRSA) on human skin before the bacteria get a chance to invade, according to a new study from Karolinska Institutet published in Cell Reports on October 29.  Discuss
Conferences
Society for Laboratory Automation and Screening (SLAS) 2020
January 25-29, 2020
San Diego, California United States
American Society for Microbiology (ASM) Biothreats
January 28-30, 2020
Arlington, Virginia United States
Festival of Genomics 2020
January 29-30, 2020
London, Greater London United Kingdom
Medlab Middle East
February 3-6, 2020
Dubai, Dubai United Arab Emirates
Japan Analytical & Scientific Instruments Show (JASIS)
November 11-13, 2020
Chiba, Chiba Japan
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Conferences
Society for Laboratory Automation and Screening (SLAS) 2020
January 25-29, 2020
San Diego, California United States
American Society for Microbiology (ASM) Biothreats
January 28-30, 2020
Arlington, Virginia United States
Festival of Genomics 2020
January 29-30, 2020
London, Greater London United Kingdom
Medlab Middle East
February 3-6, 2020
Dubai, Dubai United Arab Emirates
Japan Analytical & Scientific Instruments Show (JASIS)
November 11-13, 2020
Chiba, Chiba Japan
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