Cancer & Disease Research
Scientists learn how lactate contributes to cancer formation
Previously considered a waste product of metabolism, lactate may play a crucial role in cancer growth, according to a study published in Frontiers in Oncology on January 14. Researchers from the University of Colorado Anschutz Medical Campus explored how lactate affects transcription of oncogenes in breast cancer cells.  Discuss
Scientists in the Lab: Featuring Lisa Mustachio
Continuing our feature series this January, ScienceBoard is happy to highlight the work of laboratory scientists, including Lisa Maria Mustachio, PhD, a postdoctoral fellow at MD Anderson Cancer Center.  Discuss
Dietary probiotics show potential to reverse Parkinson's symptoms
Roundworms that were fed a commercially available dietary probiotic showed less buildup of proteins that form during the progression of Parkinson's disease in a new study, published in Cell Reports on January 14. The finding provides further evidence of a link between the gut microbiome and brain function.  Discuss
Research sheds light on how bacteria 'take one for the team'
It's already known that bacteria under assault by phages can occasionally program themselves to die before they become infected. But a pair of new papers published January 10 in Molecular Cell sheds more light on the process by which bacteria "take one for the team." The findings could provide new avenues in the treatment of multidrug-resistant bacterial infections.  Discuss
Control of molecular 'doormen' in fat cells offers potential new obesity treatment
New treatment options for obesity could emerge from a study published in Nature Communications on January 10. Researchers from Yale University School of Medicine utilized cellular and molecular approaches to identify pathways to restore the healthy balance of fat cells.  Discuss
Bacterial evolution reveals method to fight antibacterial resistance
Different types of bacteria have evolved to develop unique mechanisms for achieving the same antibacterial function -- a finding that could lead to new ways to combat antibacterial resistance, according to scientists from Trinity College Dublin. They tested their findings using methicillin-resistant Staphylococcus aureus in a study that was published in Nature Communications on January 9.  Discuss
Scientists in the Lab: Featuring Rebecca Fleeman
This month, ScienceBoard is featuring scientists in the laboratory to celebrate their important contributions to the scientific community. We are excited to introduce our first featured scientist of this month, Rebecca Fleeman of Penn State College of Medicine in Hershey, PA.  Discuss
Nanoparticles direct 'suicide genes' to treat brain tumors in children
Researchers from Johns Hopkins University report a bioengineered nanoparticle that successfully delivers a "suicide gene" to pediatric brain tumor cells implanted in the brains of mice. Details of the nanoparticle treatment were published in the January 2020 edition of Nanomedicine: Nanotechnology, Biology and Medicine.  Discuss
Improving melanoma immunotherapies by regulating Treg proliferation
A new pathway to regulating anti-tumor immunity and increasing the effectiveness of PD-1 therapies was identified by scientists at Sanford Burnham Prebys Medical Discovery Institute. The results were published in Nature Communications on January 7.  Discuss
Together, machine learning and tumor DNA provide new tools for colorectal cancer patients
Researchers utilize a new machine learning platform to identify patients with colorectal cancers and predict their disease severity and survival. The study, published in Science Translational Medicine on January 1, involves samples from over a thousand patients.  Discuss
Conferences
Society for Laboratory Automation and Screening (SLAS) 2020
January 25-29
San Diego, California United States
American Society for Microbiology (ASM) Biothreats
January 28-30
Arlington, Virginia United States
Festival of Genomics 2020
January 29-30
London, Greater London United Kingdom
Medlab Middle East
February 3-6
Dubai, Dubai United Arab Emirates
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