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Could a plant virus help create a new MRI contrast agent?
February 10, 2020 -- What's old is new for University of Texas at Dallas researchers who are resurrecting an organic, biodegradable compound that someday might be the foundation for a nongadolinium-based magnetic resonance imaging (MRI) contrast agent, according to a preclinical study published online on February 5 in Chemical Science.  Discuss
3D model of human intestines helps simulate leaky gut condition
February 10, 2020 -- Researchers are using 3D models of human intestines to simulate leaky gut conditions -- in which microbes and molecules seep out of the intestines, eliciting an immune response. The research, published in Life Science Alliance on February 10, will help identify biomarkers for leaky gut for improved diagnostics and treatment development.  Discuss
Experts map the future of bioprinting
February 7, 2020 -- Bioprinting has rapidly advanced in both techniques and clinical applications, but key challenges still remain for the burgeoning field. A multinational team of researchers offered their recommendations for how to address these hurdles in an in-depth road map article published February 7 in Biofabrication.  Discuss
Genomics sheds light on the life history of cancers
February 6, 2020 -- As part of a special collection of papers on pan-cancer analysis of whole genomes published online by Nature on February 6, an international group of scientists analyzed over 2,500 unique cancer genomes to shed light on the life history of cancer mutations and how cancer tumors evolve -- even before they are diagnosed.  Discuss
New fluorescence technique builds more vivid views
February 5, 2020 -- A novel imaging technique improves processing time of hyperspectral fluorescence imaging and allows scientists to peer more deeply and clearly into living organisms. Researchers from the University of Southern California Michelson Center for Convergent Bioscience have been developing the technology for years and have published their findings in Nature Communications on February 5.  Discuss
Hydrogels enable on-demand production of pharmaceuticals
February 4, 2020 -- A first-in-class system that effectively embeds engineered microbes into the solid support of a 3D-printed hydrogel is described in a report published in Nature Communications on February 4. The hydrogel system organizes both individual microbes and groups of microbes for on-demand production of pharmaceuticals.  Discuss
Math models improve the effectiveness of immunotherapy
February 4, 2020 -- Scientists working at the intersection of math and medicine propose new strategies based on mathematical modeling and known molecular mechanisms to improve the efficacy of lifesaving immunotherapies for cancerous tumors. The work was published on February 3 in the Proceedings of the National Academy of Sciences.  Discuss
Chinese researchers mobilize to classify 2019-nCoV
February 3, 2020 -- In response to a recent outbreak of the novel coronavirus (2019-CoV), scientists in China have uncovered genetic similarities with severe acute respiratory syndrome (SARS) coronaviruses by analyzing patient samples from the source of the outbreak. Their findings provide crucial evidence that will aid in the classification and identification of 2019-CoV, according to a new report published in Nature on February 3.  Discuss
Institut Pasteur reveals how it sequenced the coronavirus
January 31, 2020 -- On January 30, the Institut Pasteur became the first European institution to sequence the novel coronavirus (2019-nCoV) since the outbreak began in December 2019. Institut Pasteur researchers used a unique sequencing platform to confirm the presence of 2019-nCoV in three samples from suspected cases in France.  Discuss
Wuhan coronavirus spread may be vastly underestimated
January 31, 2020 -- Up to 75,800 people in the city of Wuhan, China, are estimated to be infected with the 2019 novel coronavirus (2019-nCoV), which is vastly more than official reports, according to a mathematical modeling study by Hong Kong experts that was published online January 31 in the Lancet journal.  Discuss
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