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MachineBio offers path toward single-step protein synthesis and purification
September 13, 2021 -- The next featured company in the BioTools Innovator accelerator contest is MachineBio. The company has developed a protein synthesis platform that can produce pure protein from a DNA template in a single-step process that takes four hours. We spoke with David Marash, co-founder, CEO, and head of scientific operations for MachineBio, as part of our coverage of the competition. Read More
New software finds relationships between RNA modifications, cancers
September 13, 2021 -- A new computational tool called ModTect could identify RNA modifications using preexisting sequencing data gathered from clinical cohort studies. The tool may bring scientists closer to understanding the relationships between RNA modifications and the development of cancer and other diseases, according to a recent study in Science Advances. Read More
Vaccine for tooth decay? It's not science fiction, says NIH
September 13, 2021 -- A vaccine for caries could be possible under a new division of the U.S. National Institutes of Health (NIH) that has been tasked with using "crazy, bold ideas" to prevent and cure disease. Health leaders introduced the proposed agency at a September 9 meeting of the National Institute of Dental and Craniofacial Research. Read More
New gene therapy platform shows potential against certain muscle diseases
September 10, 2021 -- Scientists have engineered a new family of adeno-associated viruses (AAVs) to deliver therapeutic genes to muscle tissue at 100 to 250 times lower doses than previous AAV vectors, potentially reducing the risk of liver damage and other serious side effects, according to a new study published in Cell on September 9. Read More
Celldom has its eye on low-cost, scalable single-cell analysis
September 9, 2021 -- Celldom, a startup based in Durham, NC, has developed a low-cost, high-throughput, single-cell analysis platform designed to investigate and classify rare cells associated with diseases like cancer. The company is one of 10 semifinalists in the BioTools Innovator accelerator contest. We spoke with co-founder and CEO Benjamin Yellen as part of our exclusive coverage of the competition. Read More
Thermo Fisher announces new spectrometers, facility, more
September 8, 2021 -- Thermo Fisher Scientific announced that it is building a manufacturing facility in Tennessee. In addition, it has released a line of spectrometers and a liquid chromatography system. Read More
Glyphic Biotechnologies is developing a single-molecule-resolution protein sequencing platform
September 7, 2021 -- Glyphic Biotechnologies is developing a novel protein sequencing platform that allows researchers to determine each amino acid in a protein sequence. The company is one of 10 semifinalists in the BioTools Innovator accelerator contest, and we spoke with co-founder and CEO Josh Yang as part of our exclusive coverage of the competition. Read More
How challenging risky ideas fuels the research ecosystem
September 3, 2021 -- If you knew that an experiment would fail, would it be worthwhile to conduct if it had the potential to challenge fundamental hypotheses about science? In a recent interview with ScienceBoard.net, world-renowned Stanford University scientist and serial entrepreneur Stephen Quake, PhD, discussed the value of basic research and his contributions to the biomedical field. Read More
How EpiCypher is quantifying and scaling chromatin science
September 2, 2021 -- EpiCypher is developing tools based on its designer nucleosome technology to enable epigenetics-focused drug development for a variety of chromatin biology applications. The company is one of 10 semifinalists in the BioTools Innovator accelerator contest. We spoke with Martis Cowles, chief business officer, as part of our exclusive coverage of the competition. Read More
Researchers figure out how the immune system sparks cell death
September 2, 2021 -- Immunologists have discovered how the innate immune system launches a multifaceted attack against invaders through the use of multiple immune sensors. The work was published in Nature on September 1. Read More
KromaTiD launches mapping service for human genome in single cells
September 2, 2021 -- KromaTiD has launched a new product called dGH Screen for mapping the human genome in single cells. The tool uses the company's proprietary directional genomic hybridization (dGH) technology, a platform for measuring genomic structure and structural variation. Read More
Sciex launches BioPhase 8800 for high-throughput capillary electrophoresis
September 1, 2021 -- Sciex has launched BioPhase 8800, a new capillary electrophoresis system for enhanced biologic characterization in the development of biopharmaceutical therapies. The new instrument is a multicapillary system for capillary electrophoresis sodium dodecyl sulfate that processes eight samples simultaneously. Read More
'Dimmable' switch for gene therapy shows potential for rare diseases
August 31, 2021 -- A new alternative splicing system called Xon can modulate levels of protein expression in gene therapy, much like a dimmer switch. The invention addresses a major shortcoming of most gene therapies, which is the ability to regulate gene expression levels in diseases like spinal muscular atrophy. Read More
Vizgen begins shipping Merscope instruments for single-cell genomics
August 30, 2021 -- Vizgen has shipped its first commercial Merscope instruments to research institutions as part of a limited summer release program. Merscope enables high-plex, single-cell spatial genomics and large-scale spatial profiling of individual transcripts within cells. Read More
Clara Biotech advances exosomes in biomedical research
August 27, 2021 -- Clara Biotech sees its exosome purification and isolation technology as a tool that can help biomedical researchers in multiple fields. The company is one of 10 semifinalists in the BioTools Innovator accelerator contest, and we spoke with co-founder and CEO Jim West as part of our exclusive coverage of the competition. Read More
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September 29 - October 3
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October 10-14
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