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Help inform tools and technologies that advance research, treatments, and cures. The Science Advisory Board is an exclusive, online community that connects scientific and medical professionals across the world.

The Science Advisory Board is an exclusive, online community that connects scientific and medical professionals across the world.

Algorithm detects unknown anomalies in RNA-seq data
November 27, 2019 -- A new computational approach to analyzing gene expression data is presented by computational biologists from Carnegie Mellon University (CMU) and published in Cell Systems on November 27.  Discuss
New chemistry technique builds more precise nanoparticles
November 27, 2019 -- New research published in Nature Communications on November 27th demonstrates a new chemical technique that provides researchers enhanced control over the size and shape of nanoparticles used in drug delivery systems.  Discuss
A discovery of fungi – helping researchers identify new drugs
November 26, 2019 -- To address the need to identify new therapeutic targets, researchers at the Hubrecht Institute turned to fungi. The researchers tested secondary metabolites from over 10,000 fungi species and identified 34 biological active compounds with the potential to move to the next step of therapeutic drug development. The research was published in Scientific Reports on November 26.  Discuss
Designer DNA traps dengue virus
November 25, 2019 -- Researchers from Rensselear Polytechnic Institute have developed a new approach to trap the dengue virus, a close relative to the Zika virus, in the bloodstream using innovative nanotechnology. The technique was published in Nature Chemistry on November 25.  Discuss
New method reveals 3D DNA structure
November 22, 2019 -- The scientist who developed a new method of illuminating 3D genomic structures, called Dip-C, is awarded the SciLifeLab Prize for Young Scientists by the Science for Life Laboratory in Sweden and the journal Science. The research of the grand prize winner, Longzhi Tan, builds on the work of the Human Genome Project by developing an algorithm to capture diploid chromosome conformation.  Discuss
Data Science Vital to Large-Scale Cellular Studies
November 21, 2019 -- Data science as a discipline has become a central aspect of many commercial endeavors. A large range of distinct applications have adopted its approaches and techniques. Despite the major differences in many of these applications, some of the techniques can be transferred from old and established data-driven fields to new, completely separate data-intensive areas. For example, certain image analysis algorithms from astronomy can be applied in fields involving microscopy.  Discuss
New genetic risk factor discovered for Alzheimer's disease
November 21, 2019 -- A new genetic risk factor for late-onset Alzheimer's disease (LOAD) has been identified by researchers from the University of Kentucky. The results of the study were published in the Journal of Neuropathology & Experimental Neurology on November 21.  Discuss
New molecular drivers of Parkinson's disease identified
November 20, 2019 -- A group of researchers at the Icahn School of Medicine at Mount Sinai have discovered new molecular drivers of Parkinson's disease (PD) and subsequently determined how they impact the function of genes involved in the disease. This was accomplished using a complex statistical technique called multiscale gene network analysis (MGNA). The results were published in Nature Communications on November 20.  Discuss
Bacterial structures are critical to the development of new antibiotics
November 19, 2019 -- A research team from Cornell University have uncovered a unique regulatory mechanism unique to bacterial that may provide crucial insight for antibiotic targeting of pathogens. The work was published in Nature Structural & Molecular Biology on November 18.  Discuss
Researchers use drug repurposing to identify new treatment for Metabolic Syndrome
November 18, 2019 -- A research team from the University of Trento find a novel method for using old drugs in new ways, specifically for Metabolic Syndrome. This revolutionary technique, published on November 18 in Nature Communications, uses a systems biology approach to investigate deregulated biological processes and identify drug repurposing candidates.  Discuss
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