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Researchers dig into how myeloid cells contribute to killing cancer
November 15, 2021 -- WASHINGTON, DC - Dr. Miriam Merad, PhD, director of the Precision Immunology Institute at the Icahn School of Medicine at Mount Sinai is working on characterizing myeloid cells in cancer patients. Merad spoke with ScienceBoard at the Society for Immunotherapy of Cancer's 2021 annual meeting. Read More
New neoadjuvant platform helps inform combo immunotherapy selection for cancers
November 13, 2021 -- WASHINGTON, DC - In order to address some of the major challenges facing the immuno-oncology field, Dr. Tom Marron, PhD, has developed a platform to help researchers decide which drugs or combination of drugs to advance toward late-stage clinical trials. Marron spoke with ScienceBoard Editor in Chief, Samantha Black, PhD, onsite at the Society for Immunotherapy of Cancer's 2021 annual meeting. Read More
Illumina for Startups pushes boundaries of genomics by supporting early-stage companies
November 12, 2021 -- Most scientists are familiar with the genomics giant Illumina, which is known for its DNA sequencing technologies. However, Illumina has an accelerator program to support early-stage startups called Illumina for Startups. ScienceBoard.net recently spoke with Amanda Cashin, PhD, who leads Illumina's accelerator programs in the U.S. and internationally. Read More
$2.7B oncology cell and gene therapy market projected for 2021
November 11, 2021 -- The global market for oncology cell and gene therapies reached $1.6 million in 2020 and is expected to reach $2.744 billion in 2021, according to a recent article in Cell and Gene Therapy Business Outlook, a sister subscription-based publication of ScienceBoard.net. Read More
Can cell therapies treat cardiovascular disease?
November 10, 2021 -- While the development of cell therapies today is largely focused on oncology indications, some companies, including Athersys, envision a future where these therapies could treat other diseases and conditions, such as cardiovascular disease. B.J. Lehmann, interim CEO of Athersys, spoke with ScienceBoard.net about a recent panel that he participated in at the Cell & Gene Meeting on the Mesa 2021. Read More
Cellaria launches new tumor modeling platform
November 10, 2021 -- Cellaria has launched a new tumor modeling platform that includes a panel of cell culture media for growing cell types, an extracellular neutral collagen matrix, and protocols for testing new drug compounds. Read More
Worm that regrows its body parts can be a 'powerful system' for life sciences research
November 9, 2021 -- Scientists have demonstrated that Hofstenia miamia, a tiny flatworm capable of regenerating everything from its brain down to its tail, can be a powerful tool to study not only regeneration but other areas such as embryogenesis. The findings were published on November 8 in the journal Developmental Cell. Read More
EY white paper details how the CGT industry can collaborate to advance the field
November 8, 2021 -- A transition from corporate individualism to teamwork and collaboration is necessary to meet the challenges that exist for companies in the cell and gene therapy (CGT) industry, according to a new white paper published by Ernst & Young (EY) on November 4. Read More
Experimental drug enhances immunotherapy against pancreatic cancer in mice
November 5, 2021 -- A combination treatment that included an experimental small molecule drug not only led to a reduction in tumor growth in murine models of pancreatic cancer, but it also eliminated the cancer in some mice. The findings were published in the Journal for ImmunoTherapy of Cancer on November 4. Read More
Online portal helps screen COVID-19 drug candidates
November 3, 2021 -- An interdisciplinary team of engineers and scientists has released DINC-COVID, a web-based portal where researchers can screen COVID-19 drug candidates that might attack specific SARS-CoV-2 proteins. Details of the new platform were published online in Computers in Biology and Medicine. Read More
How the life science industry is grappling with business challenges
November 3, 2021 -- Worldwide, the business environment is facing several challenges. Not surprisingly, these issues also impact laboratory tool companies. Tanya Samazan, managing editor of Instrument Business Outlook, spoke with Michael Copps, president and CEO of the Analytical, Life Science & Diagnostics Association, about how its members are addressing the challenges. Read More
The continued challenges of flavivirus serology
November 2, 2021 -- Flaviviruses are a genus of positive-sense RNA viruses, largely transmitted by mosquito and tick vectors that cause infections, including yellow fever, dengue, the Zika virus, West Nile virus, Japanese encephalitis, and tick-borne encephalitis. In fighting the emergence of flaviviruses, a well-established gap in our arsenal is the availability of accurate diagnostic data. Read More
Scientists explain non-small cell lung cancer treatment resistance
November 2, 2021 -- A research group has shown why certain T cells do not respond to therapy in patients with non-small cell lung cancer who receive a therapy called immune checkpoint blockade. The findings, published on October 29 in Science Immunology, suggest that a combination of immunotherapies may be a more effective approach to treating lung cancer. Read More
Trends in pharma/biopharma support the demand for analytical instrumentation
November 1, 2021 -- Strategic Directions International has observed the dynamics of the pharmaceutical and biopharmaceutical sector. Analyzing demand to support therapeutic development is crucial to the process of drug discovery. Read More
Scientists identify diagnostic gene signature for breast cancer
October 29, 2021 -- Researchers have identified a diagnostic signature for genetic mutations and other abnormalities associated with drug resistance and poor outcomes in estrogen receptor-positive metastatic breast cancers. The findings, published on October 28 in Cancer Research, may one day guide personalized treatments for cancer patients. Read More
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