Cell Biology
Future of small-molecule drugs lies in oral formulations
The way forward for small-molecule drug manufacturers is through orally administered products, according to Spiro Rombotis, president and CEO of Cyclacel, who recently spoke with ScienceBoard.net. Read More
Researchers capture new ribosome structures in motion
Researchers have captured six new structures of the ribosome and its directional movement using single-molecule fluorescence resonance energy transfer and cryogenic electron microscopy. The results were published in Nature on July 7. Read More
Researchers image mouse brain in entirety with multimodal pipeline
Researchers have successfully combined multiple imaging modalities on the same brain tissue to capture the anatomic features of neurons across the entire mouse brain. The pipeline of imaging modalities and results are detailed in NeuroImage. Read More
Machine learning helps scientists map the mammalian immune system
The use of advanced machine-learning software has led to the identification of hundreds of new genes that likely affect the working immune system, according to findings from a study published recently in the Proceedings of the National Academy of Sciences of the United States of America. Read More
BD launches new digital marketplace for flow cytometry
Becton Dickinson (BD) has launched bdbiosciences.com, an updated digital marketplace for flow cytometry. The new website provides an enhanced online purchasing experience for flow cytometry users and their procurement teams. Read More
Innovation in single-cell sequencing unlocks 10x more data from each cell
A new single-cell sequencing method yields at least 10 times more data for each individual cell compared to previous techniques. The method, published in Nature Biotechnology on July 5, may help cancer researchers uncover new insights into the biological underpinnings of cancer such as drug resistance. Read More
Algorithm expands what scientists can uncover from individual cells
A new software tool can help researchers further utilize single-cell RNA sequencing data to learn more about individual cells by incorporating biologically relevant data into the analysis. The machine-learning algorithm, detailed in Genome Research on June 30, can be used to predict which transcription factors are most active in individual cells. Read More
Oncolytic viruses move closer to becoming effective cancer therapies
Scientists are identifying key factors that aid in the effectiveness of oncolytic viruses during the treatment of cancers, which could lead to better immunotherapies and inform clinicians which patients might benefit from the treatment. Findings from a June 22 Nature Communications article point to the clinical relevance and underlying mechanisms of a novel anticancer treatment. Read More
Twist acquires iGenomX for $35M
Twist Bioscience has acquired next-generation sequencing library preparation developer iGenomX for $35 million. The deal gives Twist a leg up in the shift from genotyping with static microarray platforms to using sequencing workflows. Read More
What makes immunotherapies successful in one tumor but not in others?
Researchers have developed a new framework to uncover pathophysiological and molecular features that determine the effectiveness of immunotherapies. The research, published in Nature Communications on June 29, provides an opportunity for improving patient care and gaining a deeper understanding of cancer immunotherapy mechanisms. Read More
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