Cell Biology
Are masks effective at preventing the spread of SARS-CoV-2?
Contradictory messages over the best methods to limit the spread of SARS‑CoV‑2 have been shared with the public in past months. This has prompted scientists to explore the effectiveness of certain measures like wearing masks and the mechanisms behind transmission of the virus.  Discuss
Researchers bait viruses with chemically designed structures
A new therapeutic approach for suppressing seasonal influenza that involves synthetic phage shells that interfere with pathogen adhesion is immediately being tested for use on coronaviruses in response to the global COVID-19 pandemic. The research findings were published in Nature Nanotechnology on March 30.  Discuss
Researchers reveal vulnerabilities of 'addicted' cancer cells
New findings about the mechanism by which some cancer cells can become "addicted" to glucose could lead to fresh approaches to targeted cancer therapies. The results of the research were published in Nature Cell Biology on March 30.  Discuss
Researchers explore mutations to improve drug design
Drug resistance is a common challenge when designing therapeutics for cancers or diseases originating from bacteria or viruses. Researchers explored how evolution impacted the mutation of these pathogens, and their findings could lead to the development of evolutionarily designed drugs. The results were published March 24 in Cell Reports.  Discuss
Systems-based analysis helps researchers understand cell migration
An international team of researchers has developed a unique library to study the regulation of the cytoskeleton in space and time. The work, published in Nature Cell Biology on March 23, takes a systems-based approach to gain an overview of this process.  Discuss
New lung cancer biomarker could significantly improve patient outcomes
A new protein has been identified on tumor-derived extracellular vesicles that indicates if a lung tumor is likely to metastasize, according to research published in Science Advances on March 11. A minimally invasive biomarker test to catch cancer early could significantly improve patient outcomes.  Discuss
Gene amplification can be responsible for functional innovation in bacteria
Researchers have gained a greater understanding of how gene amplifications rapidly tune levels of gene expression when gene regulation is required but when no other molecular regulatory mechanisms are in place. This research was published in Nature Ecology & Evolution on March 9.  Discuss
New machinery digests toxic proteins to protect DNA replication
Researchers have identified molecular machinery that helps repair damaged DNA that occurs during DNA replication and transcription. This work, published in Nature Communications on March 9, reveals how specific enzymes "eat" or break down proteins that cause broken DNA.  Discuss
Bacteria survive by possessing multiple genes to uptake the same amino acid
Researchers have long known that the uptake systems in clonal cells can differ based on their environments. Scientists reported their observations of this amino acid uptake pathway in bacteria for the first time in a new study published March 5 in Nature Communications.  Discuss
Extra copies of chromosomes can be good or bad
Researchers are developing human cell lines to explore how extra copies of chromosomes can enhance the metastasis and invasiveness of cancer cells. They explained their methodology in a study published in Developmental Cell on February 24.  Discuss
Conferences
2nd Annual Cell Therapy Bioprocessing Conference
June 25-26
Boston, Massachusetts United States
BioProcess International Europe
July 13-16
Amsterdam, Noord-Holland Netherlands
Bioprocess International West
August 10-13
Santa Clara, California United States
BioProcess International
September 21-24
Boston, Massachusetts United States
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