In an attempt to combat bacterial infections, Locus Biosciences is developing bacteriophage therapies that deliver CRISPR-Cas3 machinery directly to specific, targeted pathogens to obliterate them. Locus CEO Paul Garofolo discusses the company's technology and recent updates with The ScienceBoard.net. Discuss
A new model used to predict the outcomes of pathogen detection systems as a function of innate immunity may lead to more effective cancer immunotherapies and vaccines against existing and novel pathogens, according to results published in Cell Systems on October 27. Discuss
A new CRISPR tool utilizes Cas3 to remove larger than normal stretches of DNA both quickly and accurately. The tool, described in an October 19 article in Nature Methods, could help fill a void in current gene editing capabilities. Discuss
The National Institute of Allergy and Infectious Diseases, part of the U.S. National Institutes of Health (NIH), has awarded 11 grants for a first-year total value of approximately $17 million to establish the Centers for Research in Emerging Infectious Diseases. Discuss
A microbe-based therapeutics platform that has been in development for nearly 30 years is gaining traction for the treatment of inflammatory and autoimmune diseases. The company that is developing the platform, Precigen ActoBio, is advancing a lead candidate through clinical trials with the long-term goal of finding a sweet spot between biologics and gene therapies. Discuss
Genetic analysis of antibodies reveals how microbes in the intestines impact overall B-cell populations and humoral responses to pathogens. The research was published in Nature on August 5. Discuss
A new graphical user interface-driven, machine learning-based approach has successfully identified antimicrobial resistance genes for gram-positive and -negative bacteria. This work, presented in Scientific Reports on July 3, may make it easier to identify deadly antimicrobial-resistant bacteria. Discuss
A new paper published in the International Journal of Systematic and Evolutionary Microbiology proposes major changes to the classification and naming of Lactobacillus probiotics based on new information gained by modern DNA analysis tools. Discuss
A research collaboration between scientists at the University of Leeds and AstraZeneca resulted in the development of a technique that can significantly reduce the discovery time for possible new antibody-based therapies. The approach, published in Nature Communications on April 14, shows how protein fragments can be screened for susceptibility to aggregation in early drug discovery. Discuss
Researchers have developed a new aquaculture-based method to harvest immune cells from horseshoe crabs that preserves the crustaceans while also creating the potential for new clinical applications, like testing blood for sepsis, according to a study published in Frontiers in Marine Science on April 1. Discuss
Conferences
2020 AACC Annual Scientific Meeting & Clinical Lab Expo
December 13-17
Online
December 13-17
Online
Society for Laboratory Automation and Screening (SLAS) 2021
January 23-27, 2021
Online
January 23-27, 2021
Online
Festival of Genomics & Biodata
January 28-29, 2021
London, Greater London United Kingdom
January 28-29, 2021
London, Greater London United Kingdom
4th Annual Cell & Gene Therapy Innovation Leaders Summit 2021 Visualising The Future
February 1-3, 2021
Berlin, Berlin Germany
February 1-3, 2021
Berlin, Berlin Germany
Lab of the Future USA
May 11-12, 2021
Boston, Massachusetts United States
May 11-12, 2021
Boston, Massachusetts United States
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