Cell Biology
How one company is helping make complex medicines safer
Often, the most dangerous things in life are things that the human eye cannot see. This is true even for life-saving medicines. One company was founded to help the industry find these hidden particles and solve a key challenge in the development of complex drug products. Halo Labs’ CEO Rick Gordon spoke with ScienceBoard about how its low volume approach is providing a critical service for the drug development industry. Read More
Federal R&D funding for universities tops 3% in fiscal year 2021
Federally funded R&D for U.S. higher education universities grew 3.3% to $86.4 billion in fiscal year 2021 (end-September 30, 2021), according to the latest statistics from the National Science Foundation. Funding from the federal government accounted for 53% of the total and increased 3.7%. Read More
Newfound understanding of tissue migration can harness cancer spread
New research has uncovered mechanistic details in living tissue that explain how tissue exercises physical stresses to induce motion in vivo. The study, published in Nature Cell Biology on February 14, documents that the rear end of moving tissue plays a primary role in pushing tissue forward. This finding could be the basis for understanding organ development and the spread of cancer. Read More
Machine vision advances single-cell sequencing for small samples
The ability to sequence RNA in single cells has given scientists an unprecedented level of resolution in studying rare cell types. However, current approaches are designed to deal with a large number of cells, making it difficult to work with small samples. New research, published in Nature Methods on February 14, has described a technique using machine vision to detect cells and make single-cell RNA sequencing more efficient at a smaller scale. Read More
Colonic gene mapping provides insights into intestinal diseases
Researchers have used spatial transcriptomics to uncover an unprecedented view of the molecular regionalization of the murine colon. This research, published in Nature Communications on February 11, provides novel insights into inflammatory bowel disease. Read More
IsoPlexis uses proteomics to identify early factors of long COVID
IsoPlexis has published a study in Cell, led by the Institute for Systems Biology and the Seattle COVID Consortium, in which researchers used IsoPlexis' single-cell functional proteomics platform to identify factors that may predict sustained disease after COVID-19 infection, also known as post-acute sequelae of COVID-19 (PASC) or long COVID. Read More
What will digital transformation in research labs look like?
BOSTON - Data communication and management are crucial for digital transformation and the acceleration of important scientific discoveries, according to Sridhar Iyengar, CEO of Elemental Machines. Iyengar gave a presentation titled "Why Data Maturity Is Essential to the Lab of the Future" at the Society for Laboratory Automation and Screening 2022 International Conference and Expo on February 7. Read More
Atlas finds hundreds of genes that control the brain's shape
The shapes of our brains are heavily influenced by our genes, although the precise nature of this complex relationship is difficult to pin down. Now, a study published on February 3 in Science has used a genetics-based atlas of the cerebral cortex to identify hundreds of new gene variants that are linked to growth of specific regions. Read More
New genetic benchmark improves the diagnosis of several diseases
The Genome in a Bottle consortium has documented a benchmark set of challenging, medically relevant autosomal genes with a haplotype-resolved, whole-genome assembly that are associated with several diseases. The details of the research were published in Nature Biotechnology on February 7. Read More
How to future ready businesses with diversity, equity, inclusion
BOSTON - What practices should organizations in the life sciences deploy to attract, develop, and retain the future workforce? Keynote speaker at the Society for Laboratory Automation and Screening 2022 conference, Raven Solomon, a diversity, equity, and inclusion (DEI) thought leader, provided a business case why DEI should be a priority for businesses. Read More
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