Production technique clears barrier to widespread study of intestinal organoids The aggregation of cells removes variability from the production of small intestinal organoids, clearing a major hurdle to the widespread use of the technologies as a research tool for studying the digestive system, according to a paper published July 28 in Stem Cell Reports.Read More
Video from AACC: Lab Ordering Cloud software Mehdi Maghsoodnia, CEO of 1health, spoke to ScienceBoard.net's sister site LabPulse.com about the market needs for the firm’s Lab Ordering Cloud, as well as diagnostic industry trends.Read More
RNA molecules identified as potential ‘common driver’ of cancer progression Moffitt Cancer Center researchers have challenged the widely held view that protein structure and function are the key drivers of cancer development. Their study found competitive endogenous RNA drive melanoma growth and metastasis by blocking the antitumor activity of other molecules.Read More
Researchers capture images of antibody attacking neuron receptor U.S. and German researchers have captured the first images of an antibody attacking a nerve cell surface receptor using cryo-electron microscopy, a technique that freezes proteins in place to get high-resolution microscopic images, according to a study published in Cell.Read More
Machine learning model opens door to real-time detection of cell therapy contamination Researchers at the Massachusetts Institute of Technology’s Singapore site have developed a new way to detect adventitious microbial contamination in mesenchymal stromal cell cultures. By using machine learning to predict if a culture is contaminated in near real-time, the approach could enable testing to take place during the production of cell therapy products.Read More
Endosomal pH drives stemness in glioblastoma A group of researchers has shown that endosomal pH drives stemness in glioblastoma. The group discovered that endosomal Na+/H+ exchanger isoform 9 is a novel driver of stem cell-like characteristics -- or stemness -- in glioblastoma by stabilizing multiple receptor tyrosine kinases, according to a recent paper published in PNAS Nexus.Read More