Analytical Chemistry
Scientists identify chaperones as potential therapies for Parkinson's disease
Researchers from the University of Basel have identified the malfunctional relationship and master regulatory mechanisms between chaperone proteins and α-Synuclein occurring in Parkinson's disease. The findings were published in Nature on December 4.  Discuss
New chemistry technique builds more precise nanoparticles
New research published in Nature Communications on November 27th demonstrates a new chemical technique that provides researchers enhanced control over the size and shape of nanoparticles used in drug delivery systems.  Discuss
A discovery of fungi – helping researchers identify new drugs
To address the need to identify new therapeutic targets, researchers at the Hubrecht Institute turned to fungi. The researchers tested secondary metabolites from over 10,000 fungi species and identified 34 biological active compounds with the potential to move to the next step of therapeutic drug development. The research was published in Scientific Reports on November 26.  Discuss
Novel strategy for studying mitoribosomal and mitochondrial impact on disease
Researchers from the Karolinska Institutet in Sweden have developed a new experimental tool for studying mitochondrial protein synthesis in vivo. This research is presented in the October 5 issue of Cell Reports.  Discuss
New bio-imaging techniques help scientists understand the early stages of Parkinson's disease
Scientists observed, for the first time ever, how variants of Parkinson's disease-associated protein alpha-synuclein change over time and identify the initial stages of protein aggregates. A new study published in Nature Communications on October 10 helps to clarify the why treatment challenges associated with Parkinson's disease (PD), when does it begin.  Discuss
Chemists develop new technique to build super-active catalysts
New highly desirable catalysts, made mostly of precious metals, have 24 different faces that present atoms at the surface in ways that make them more catalytically active than current commercially available products.  Discuss
Breakthrough electrochemical technique may bring cost savings to drug companies
Researchers have developed a simple new method for the creation of hindered ether compounds, which are often important components of many drugs and commercial products. Hindered ethers have been traditionally difficult to manufacture, but scientists at Scripps Research have published a new electrochemistry technique in Nature on September 9, which allows these compounds to be produced faster and more efficiently.  Discuss
New targeted therapy for lung cancer using precious metals as Trojan exosomes
Researchers at the University of Edinburgh and the Universidad de Zaragoza in Spain present a novel therapeutic approach to treating cancer on September 9. The research using exosome-directed catalyst prodrug therapies was published in Nature Catalysis.  Discuss
Fluorescent molecular probe used to detect temperature inside individual cells
Modified biocompatible molecular rotor, termed boron dipyrromethene (BODIPY), has been shown to detect temperatures inside single cells. Researchers at Rice University led by chemist Angel Martí published the technique in the Journal of Physical Chemistry B.  Discuss
Biologically active molecules in coal are found to have antiviral properties against tick-borne encephalitis
Scientists from Russia demonstrated in a Scientific Reports article published on August 19, that biologically active molecular components of substances extracted from coal, humic substances, have antiviral properties. A novel approach to identify these molecules determined that these molecules inhibit the reproduction of tick-borne encephalitis virus (TBEV), which causes clinically relevant human viral infectious disease.  Discuss
Conferences
Society for Laboratory Automation and Screening (SLAS) 2020
January 25-29, 2020
San Diego, California United States
American Society for Microbiology (ASM) Biothreats
January 28-30, 2020
Arlington, Virginia United States
Festival of Genomics 2020
January 29-30, 2020
London, Greater London United Kingdom
Medlab Middle East
February 3-6, 2020
Dubai, Dubai United Arab Emirates
Japan Analytical & Scientific Instruments Show (JASIS)
November 11-13, 2020
Chiba, Chiba Japan
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