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Preclinical data on long-acting tuberculosis drug raises hopes for simplified treatment
A long-acting injectable formulation of rifabutin has delivered high plasma concentrations for 16 weeks in mice, resulting in the prevention of tuberculosis and the clearing of the pathogen from the lungs.
Hydrogel proves to be immunity-boosting postoperative treatment in mouse models of human glioblastoma
A new injectable hydrogel developed by University of Wisconsin-Madison researchers has been successfully used as an immunity-boosting postoperative treatment in mouse models of human glioblastoma, one of the most complex, deadly, and treatment-resistant cancers that begin within the brain.
NIH team creates 3D structure of twinkle protein, sheds light on mitochondrial diseases
Researchers from the National Institutes of Health (NIH) have used cryo-electron microscopy and other techniques to create a 3D structure of the twinkle protein, the final piece of the human minimal mitochondrial replisome to be structurally characterized.
Molecular, genetic mechanisms of microglia predispose individuals to Alzheimer's: study
Mount Sinai researchers contend they have achieved an “unprecedented” understanding of the genetic and molecular mechanisms in human microglia, immune cells that reside in the brain, providing insights into how they contribute to the development and progression of Alzheimer’s disease.
Link between genes, mitochondrial DNA reveals way to tackle cardiovascular disease
The discovery of a link between mitochondria, inflammation, and a pair of genes that help regulate blood cell growth has revealed a potential new target for atherosclerosis therapies.
First full map of immune system connections unlocks drug discovery opportunities
Researchers have created the first full map of immune system connections showing how immune cells communicate, pointing to ways to modulate the pathways to treat cancer and infectious diseases.
Technology restores cell, organ function in pigs an hour after their deaths
Yale University scientists were able to restore blood circulation and other cellular functions in pigs a full hour after their deaths from cardiac arrest by using technology that delivers a specially designed cell-protective fluid to organs and tissues, according to a paper published August 3 in the journal
Adjuvanted liposomal vaccine protects baby mice from RSV, looks promising for human newborns
After a more than 50-year wait, a vaccine to protect infants from respiratory syncytial virus (RSV) -- the leading global cause of death in children under age five -- could finally become a reality. A single dose of an adjuvanted liposomal vaccine formulation has induced protection against RSV infection in baby mice.
Video from AACC: First impressions, Day 1
Reflecting on highlights from the
team for Day 1, Kalorama Information's Bruce Carlson compares AACC 2022 with previous meetings.
Researchers identify T cells that protect against ischemic stroke in mice
University of Pittsburgh neurologists and immunologists have identified a subset of CD8+ regulatory-like T cells (CD8+TRLs) that provide fast-acting and lasting protection against ischemic stroke in mice, offering a potentially novel immunotherapy for stroke in humans.
Glasgow International Health Festival
Glasgow, Glasgow City United Kingdom
Sales and Marketing Professionals in Science Annual Meeting
Pharma Competitive Intelligence Conference and Exhibition
Newark, New Jersey United States
BioProcess International (BPI) Conference
Boston, Massachusetts United States
Laboratory Products Association Annual Meeting
Scottsdale, Arizona United States
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Spatial transcriptomics enables genetic mapping of tumors, revealing how cancers grow
Researchers further understanding of microglia, immune cells that reside in the brain
Molecule inhibits drug-resistant bacteria in mice with pneumonia, UTIs
Georgetown gets $12.5M NSF award to create institute for emerging virus research
AI, computer models of brain cells open door to experiments not possible in lab
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