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EGFR-targeting cell penetrating peptide treats triple-negative breast cancer in mice
A cell penetrating peptide designed to mimic an epidermal growth factor receptor (EGFR) binding domain has induced tumor regression in mice, opening up a new avenue of research into the treatment of triple-negative breast cancer.
Identification of genetic drivers of radiotherapy sensitivity opens door to treatment optimization
Using in silico and experimental profiling platforms, researchers at Northwestern Medicine have identified genetic biomarkers of radiation sensitivity, pointing to opportunities to use genomics to guide radiotherapy treatment for cancer patients.
Bacterium promotes pancreatic cancer growth, adding to evidence of role of tumor microbiome
Virginia Tech researchers have discovered that infection with a bacterium causes pancreatic cells to release cytokines that promote solid tumor growth, potentially helping to guide future therapeutic interventions for cancer treatment.
Antibodies hit drug-resistant cancer cells to improve durability of targeted therapies
Scientists at the Perlmutter Cancer Center at New York University Langone Health have created antibodies designed to target and kill cells that develop resistance to targeted therapies, thereby tackling a barrier to durable anticancer effects.
Mechanistic link between mutation, brain cancer opens up R&D opportunities
Researchers have identified the mechanisms that mean people with a single nucleotide polymorphism have an increased risk of a subtype of brain tumors.
Tumor-promoting mutation linked to suppression of anticancer immune response
Mutations that support the growth of tumor cells may also inhibit T cells, preventing the immune system from responding effectively to emerging cancers, according to Harvard Medical School researchers.
Nanoparticles enhance effect of brain stimulation on stroke recovery in rats
Combining nasally administered nanoparticles and noninvasive brain stimulation improves the recovery of ischemic stroke in rats, according to researchers from Xi’an Jiaotong-Liverpool University and other universities in China.
Biotech licenses drug discovery platform from Harvard, Tufts to study complex CNS diseases
Unravel Biosciences has licensed a drug discovery platform from Harvard University and Tufts University to decode and model complex central nervous system (CNS) diseases.
CRISPR edited rat embryos reveal cause of rare pediatric neurodegenerative disease
Using CRISPR gene editing technology on rat embryos, University of Wisconsin-Madison researchers have revealed the mutation that is responsible for progressive gait abnormalities and other symptoms in human infants and young children with a rare neurodegenerative disease.
New AI tool discovers mutations linking bladder cancer to tobacco smoking
Using a new artificial intelligence (AI) tool, University of California, San Diego researchers contend they have for the first time uncovered a pattern of DNA mutations that links bladder cancer to tobacco smoking.
Cell Bio 2022
District of Columbia United States
Glasgow International Health Festival
January 25-26, 2023
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NIH awards $3M grant to investigate Candida auris fungus treatment
Scientists uncover DNA repair mechanism, potential cancer target
Gene mutation may explain Alzheimer's brain plaque buildup
Scientists highlight new insights into triple-negative breast cancer
Increasing immune cell production may reverse cognitive decline: study
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