BioMérieux researchers describe rise of multi-drug resistant Candida auris infections
Researchers at diagnostic company BioMérieux conducted a retrospective analysis of blood cultures positive for Candida auris (C. auris) and found an upsurge in the detection of this emerging fungal pathogen between 2021 and 2023. Read More
Chikungunya vaccine candidate in clinical trial found generally safe and effective
A study of U.S. adults found that a vaccine candidate for chikungunya disease was generally safe and well tolerated. Read More
Bioengineered drug fights Staphylococcus infection
Early tests show that a bioengineered drug can counter infection with Staphylococcus aureus, a major cause of death in hospital patients. The research, published Monday in Cell Host & Microbe, demonstrated that the antibacterial biologic agent was superior to standard antibiotic drugs at treating S. aureus-infected mice, including its treatment-resistant form methicillin-resistant S. aureus (MRSA). Read More
Bile salt analog prevents C. diff infection in mice, advancing work to stop killer bacterium
A bile salt analog prevented Clostridioides difficile infection (CDI) in mice, pointing to a potential way to minimize the impact of a bacterium that kills 20,000 people a year. Read More
Immune system power may lessen reliance on antibiotics for tuberculosis
Francis Crick Institute researchers have found that the body’s natural process of removing old and damaged cell parts may be an essential part of tackling infections like tuberculosis (TB) that take hold within cells. They hypothesized that harnessing this process might present alternatives to antibiotics or improve antibiotic use. Their study was published in Nature Microbiology on Friday -- World TB Day. Read More
Contagious fungal infections increase dramatically
According to national surveillance data, candidiasis cases caused by Candida auris, a highly infectious fungus, rose drastically between 2019 and 2021, reflecting increased transmission. Read More
Discovery of severe form of mpox spurs call for update to list of AIDS-defining diseases
Researchers have identified a new, severe form of mpox that has a 15% mortality rate in people with advanced HIV disease and immunosuppression. Read More
Ebola vaccine protocols found safe for all ages
Two randomized, placebo-controlled trials evaluating three Ebola vaccine administration strategies in adults and children found that all regimens were safe in both age groups. The research, published last week in the New England Journal of Medicine, was conducted under the international consortium Partnership for Research on Ebola Vaccination (PREVAC). Read More
Genomics profiling reveals how Zika infects immune cells, suggests antiviral target
A genomics profiling method has revealed how the Zika virus infects human dendritic cells, pointing to a potential target for therapeutic suppression of the pathogen. Read More
First full map of immune system connections unlocks drug discovery opportunities
Researchers have created the first full map of immune system connections showing how immune cells communicate, pointing to ways to modulate the pathways to treat cancer and infectious diseases. Read More
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