Cancer & Disease Research
ARM, NIIMBL offer best practices, standards for cell therapy manufacturing challenges
The Alliance for Regenerative Medicine (ARM) and the National Institute for Innovation in Manufacturing BioPharmaceuticals (NIIMBL) have released best practices and a standard methodology intended to assist the cell-based therapy field with its ongoing manufacturing challenges. Read More
3D imaging reveals picture of T-cell activity to unlock solid tumor opportunity
Researchers have used imaging and transcriptomics to identify T cells with potent serial killing capacity in a push to expand use of the immunotherapies to solid tumors. Read More
Studies uncover findings on antibody responses, immunity
Findings from two studies add to a growing body of knowledge that is essential for guiding public health initiatives and might one day enable clinicians to assess individuals’ immunity to SARS-CoV-2, according to AACC. Read More
Research shows heart-damaging route of SARS-CoV-2 spike protein
Researchers have demonstrated that the spike protein from the SARS-CoV-2 virus can lead to heart muscle injury through the inflammation process, according to preliminary research to be presented this week at the American Heart Association’s 2022 Basic Cardiovascular Sciences Scientific Sessions. Read More
Scientists discover biomarkers associated with acute, chronic phases of TBI
Arizona State University scientists have provided some of the first detailed view of the molecular and cellular mechanisms behind traumatic brain injury (TBI) as the condition progresses from the acute to the chronic phase. Read More
Analysis of nanoparticles, cancer cells could aid development of nanoparticle-based drugs
Researchers have identified biomarkers that predict whether different types of cancer cells will take up specific nanoparticles, potentially helping to overcome some obstacles to the development of nanoparticle-based drugs. Read More
New DNA editing tool could enable more personalized cell therapies
University of Minnesota, Twin Cities researchers have developed a new tool to predict and customize the rate of a type of DNA editing called site-specific recombination, offering the potential for more personalized cell therapies. Read More
Repetitive DNA linked to cancer formation in study of replication process
Researchers have discovered that noncoding "junk" DNA could potentially contribute to the development of cancer. Repetitive DNA sequences can cause replication to stall, triggering a response that is similar to the one induced by DNA damage, according to a study published July 19 in Nature Communications. Read More
Current COVID-19 boosters provide protections against serious infection: study
Despite the evolution of the SARS-CoV-2 pandemic coronavirus, a new laboratory study conducted by a team of international researchers suggests current vaccine boosters may elicit sufficient immune protection against severe omicron-induced COVID-19 disease. Read More
Single-cell analyses shed light on drug resistance of melanoma brain metastases
Using single-cell genetic analyses of frozen brain samples, Columbia University researchers have uncovered evidence of how melanoma brain metastases evade current treatments. Read More
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