Cancer & Disease Research
CAR T-cells show preliminary efficacy, safety as solid-tumor treatment
Researchers presented phase I/II preliminary clinical trial data demonstrating the safety and efficacy of a new CAR T-cell therapy that can be used as either a monotherapy or a combination therapy to treat Claudin 6-positive solid tumors. The findings were presented at the American Association for Cancer Research Annual Meeting 2022 in New Orleans. Read More
Video from AACR 2022: Next-gen pathology tools for cancer research
NEW ORLEANS - What do the next-generation of pathology tools for cancer research look like, and how can pathologists contribute to those technologies to make an impact in their discipline? Dr. Beatrice Knudsen, PhD, of the Huntsman Cancer Institute at the University of Utah, explored these ideas at the American Association for Cancer Research (AACR) meeting in a video update from day two of the conference. Read More
Focus on drug-manufacturing optimization prioritizes patient health
As medical innovations and therapeutics advance rapidly and dramatically increase in scale, there is a critical need for manufacturing processes that can keep up with this pace. This often calls for updates, overhauls, and collaboration among companies to maintain such a high standard of production. Read More
Investment into regenerative medicine grows alongside company collaborations
Regenerative medicine is a relatively new area of medicine that involves significant research into how to harness the body's own healing mechanisms as treatments for a variety of diseases, including cardiovascular diseases, diabetes, and osteoarthritis. This is performed through the use of stem cell therapies, tissue engineering, and medical devices. The field is rapidly expanding, with many companies forming strategic research partnerships. Read More
Creating an opening for treatments into the brains of mice
The cellular barrier that protects the brain also has the unfortunate effect of preventing medical treatments from reaching areas of the brain where they are needed. This presents a major obstacle in developing new drugs to treat brain diseases. Now, in a study published in Nature Protocols, researchers describe an approach in mice to precisely open a gate in the barrier and deliver therapeutic agents. Read More
CAR T-cell therapy collaborations expand cancer treatment options
Considering the broad range of the causes of cancer and the heavy impact on patients, advanced and innovative treatments are essential to fighting it. One technology being explored for this purpose is CAR T-cell therapy, because it trains the body's immune system to specifically target cancerous cells, according to Cell and Gene Therapy Business Outlook, a sister publication of ScienceBoard. Some healthcare institutions are collaborating with companies to develop such technologies, including Celularity, Lonza, and the Memorial Sloan Kettering Cancer Center. Read More
Developments in cell therapy boost potential for autoimmune disease treatments
Healthcare leaders are working together to change the therapeutic landscape for autoimmune diseases, which are often due to unknown causes, according to Cell and Gene Therapy Business Outlook, a sister publication of ScienceBoard. Atara Biotherapeutics, Kyverna Therapeutics, and the National Institutes of Health are a few organizations that are dedicated to finding treatments for patients with limited options. Read More
ARM update points to strong 2022 for cell and gene therapy industry
Despite a turbulent investment year, the cell and gene therapy space continued to innovate and develop at an extraordinary speed, according to the "Cell & Gene State of the Industry Briefing," which was delivered on January 11 by the Alliance for Regenerative Medicine (ARM) in partnership with Biotech Showcase. Read More
CAR T cells produced in vivo may treat cardiac injury
New evidence suggests that immunotherapy could have the potential to temporarily reprogram patients' immune cells to attack a specific target via a single injection of mRNA. The study, published in Science, could lead to a new treatment for heart failure. Read More
Rare disease treatments continue to advance alongside gene therapies
Rare diseases represent an underserved and frequently overlooked area in healthcare. As a result, funding for research in these diseases is often limited. However, many of these diseases are fatal or highly impair a patient's quality of life. According to a recent report from Cell and Gene Therapy Business Outlook, a sister publication of ScienceBoard, some institutions are focusing their efforts in the area of rare diseases. Read More
Conferences
International Society for Cell and Gene Therapy Annual Meeting
May 4 - June 7
San Francisco, California United States
Interphex 2022 Conference
May 24-26
New York, New York United States
American Society for Mass Spectrometry Annual Conference
June 5-9
Minneapolis, Minnesota United States
American Society for Microbiology Microbe Meeting
June 9-13
District of Columbia United States
HPLC 2022
June 18-23
San Diego, California United States
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