Antiviral-antibody combination improves influenza outcomes in mice Researchers at McMaster University found in a mouse study that combining a class of well-known antiviral drugs and neutralizing antibodies was more effective than either approach alone, which they contend could be used to treat seasonal influenza and help prevent the next flu pandemic.Read More
Researchers capture images of antibody attacking neuron receptor U.S. and German researchers have captured the first images of an antibody attacking a nerve cell surface receptor using cryo-electron microscopy, a technique that freezes proteins in place to get high-resolution microscopic images, according to a study published in Cell.Read More
Protein crystallography links rigid antibody hinges to increased anticancer activity Researchers at the University of Southampton have gained new insight into the key properties of an antibody needed to fight off cancer using protein crystallography, revealing that the flexibility of the hinge between the arms of IgG2 antibodies affects the anticancer effects triggered by the molecules.Read More
MASTER technology could transform CAR T-cell therapy A new technology that helps CAR T cells attack cancer cells more aggressively than conventional methods has been published by researchers from North Carolina. Called multifunctional alginate scaffold for T-cell engineering and release (MASTER), the technology was described in a paper published on March 24 in Nature Biotechnology.Read More
Gene therapy shows long-term benefits for children with WAS A lentiviral-based gene therapy treatment for children with Wiskott-Aldrich Syndrome (WAS) has demonstrated long-term benefits, according to research recently published in Nature Medicine. The findings demonstrate a safe alternative to the traditional treatment protocol.Read More