Immunology Sponsored by Beckman Coulter
Study investigates pharmacogenomics of COVID-19 therapies
Human genetic variation may alter the interactions of drugs being used to treat patients with COVID-19 symptoms, resulting in a range of clinical responses -- from no effect to high toxicity in some patients, according to a study published in Nature Genomic Medicine on August 18.  Discuss
New mouse-adapted model helps accelerate COVID-19 vaccines, therapies
A new mouse-adapted SARS-CoV-2 model developed with engineered virus can help accelerate vaccine and therapeutic candidates to clinical trials. The results of the preclinical studies were published in Nature on August 27.  Discuss
NIH establishes Centers for Research in Emerging Infectious Diseases
The National Institute of Allergy and Infectious Diseases, part of the U.S. National Institutes of Health (NIH), has awarded 11 grants for a first-year total value of approximately $17 million to establish the Centers for Research in Emerging Infectious Diseases.  Discuss
Will a COVID-19 vaccine really let us go 'back to normal'?
Will the arrival of a COVID-19 vaccine be enough to allow society to go "back to normal" in the near future? The answer to that question depends on a wide range of variables, such as how effective the vaccine is and how many people get vaccinated, according to an article published in the American Journal of Preventive Medicine on August 25.  Discuss
Pharmacists issue guidance for mass COVID-19 vaccination
As society prepares for the rollout of COVID-19 vaccines, the American Society of Health-System Pharmacists has issued 10 guiding principles for development, distribution, allocation, and oversight of vaccines. The guidelines build on the organization's research and best practices expertise in pandemic preparedness, supply chain management, distribution, and clinical practice.  Discuss
Maps of natural killer cells offer insight into COVID-19 immune response
New research that sought to classify immune white blood cells, called natural killer cells, during COVID-19 infection revealed that certain cellular subtypes may contribute to the severity of disease progression, according to a recent Science Immunology article.  Discuss
Cytokines may prevent COVID-19 patients from producing the 'best' antibodies
High levels of some cytokines associated with COVID-19 could prevent long-term antibody responses to the SARS-CoV-2 virus, according to a new study published in Cell on August 19. The findings could explain why immunity to the novel coronavirus does not last long among individuals after they recover from the disease.  Discuss
SARS-CoV-2 spike protein hinges like leg joints to seek receptors
New research demonstrates that the SARS-CoV-2 spike protein may be more flexible than previously thought, with hinges similar to leg joints to seek receptors on a host, according to a new article published in Science on August 18. Understanding molecular dynamics of how the spike protein functions could have implications in therapeutic and vaccine design.  Discuss
Rare immune stem cells could lead to treatments for COVID-19, cancer
Rare stem cells that give rise to neutrophils in human bone marrow could offer a path to developing treatments for diseases that involve the white blood cells, according to a new article published in Immunity on August 18.  Discuss
Microbe-based platform aims for sweet spot between biologics and gene therapy
A microbe-based therapeutics platform that has been in development for nearly 30 years is gaining traction for the treatment of inflammatory and autoimmune diseases. The company that is developing the platform, Precigen ActoBio, is advancing a lead candidate through clinical trials with the long-term goal of finding a sweet spot between biologics and gene therapies.  Discuss
Conferences
ESMO Virtual Congress 2020
September 14-29
Online
BioProcess International West
September 21-25
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BioProcess International
September 21-25
Online
ASGCT 2020 Policy Summit
September 23-25
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