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Immunosuppressive pathway offers explanation for failure of TIGIT clinical trials
Albert Einstein College of Medicine scientists in a new analysis of the immunosuppressive KIR2DL5/PVR pathway provide a potential explanation for why anti-TIGIT therapies have failed in clinical trials.
Fentanyl vaccine stops opioid entering the brain in rats, clearing path to human studies
A fentanyl vaccine has generated antibodies against the potent synthetic opioid in rats, pointing to a way to address opioid use disorder in humans.
DNA barcoding shows how breast cancer cells evade the immune system
Using DNA barcodes, scientists at Australia’s Garvan Institute of Medical Research have revealed how cancer cells can evade the immune system and render immunotherapies ineffective.
Discovery of immune cell functionality could improve vaccine design
Using specially bred mice, Rutgers University researchers have differentiated the functions of two types of immune cells -- known as tissue-resident memory T cells -- that protect against infection and cancer, with the potential to improve vaccine efficacy as well as combat autoimmune diseases.
Genetic timestamping model reveals lifespan of cells behind vaccine-induced immunity
A genetic timestamping mouse model has shown the rate at which antibody-producing cells accumulate and disappear after vaccination, which could ultimately allow researchers to be able to increase the longevity of immunity from vaccines.
Genomics profiling reveals how Zika infects immune cells, suggests antiviral target
A genomics profiling method has revealed how the Zika virus infects human dendritic cells, pointing to a potential target for therapeutic suppression of the pathogen.
Inhibiting white blood cell enzyme reduces lung metastases in mice: study
Researchers at The Wistar Institute and Jubilant Therapeutics have found an enzyme in neutrophils that promotes tumor growth and metastasis, pointing to a new way to treat cancers.
Stanford platform improves hunt for antigens that trigger strong immune responses
Researchers at Stanford University have developed a method for making faster, more accurate predictions of which antigens will trigger a strong immune response. Their work could help scientists develop more effective cancer immunotherapies.
Blocking key enzyme boosts anticancer T-cell responses, resistance to immunosuppression
Blocking a key enzyme boosts anticancer T-cell responses and resistance to immunosuppression, according to a mice study from LSU Health New Orleans published August 26 in
Frontiers in Immunology.
Oncolytic virotherapy, immunotherapy combo shows promise for treatment-resistant cancers
A combination of oncolytic virotherapy, a technique using cancer-fighting viruses, acting in concert with immunotherapy shows promise for treatment-resistant cancers, according to new research.
More Conferences »»
MinervaX announces funding for Group B Streptococcus vaccine
Critical inhibitory site in enzyme leads to new antibiotic
B cells hinder intestinal healing, offer potential IBD drug target
mRNA vaccines may help combat malaria
Researchers discover new form of undetectable antimicrobial resistance
More articles »
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