The Science Advisory Board

Could a MERS vaccine candidate be the answer for COVID-19?
As researchers urgently work to develop vaccines to prevent COVID-19, many strategies have been considered. Now, a parainfluenza virus 5-based vaccine expressing MERS-CoV spike protein may provide an avenue for a COVID-19 vaccine based on the similarity of the two viruses, according to a study published in mBio on April 7. Discuss

3 reasons the coronavirus outbreak has been so severe
WASHINGTON, DC - Why has the current outbreak of coronavirus been so severe compared with past epidemics of viral respiratory diseases? It has to do with unique characteristics of the coronavirus itself, according to a speaker at a February 26 congressional briefing. Discuss

Breakthrough in coronavirus research provides map for vaccines
Critical research reveals the 3D atomic-scale map of the spike protein of the 2019 novel coronavirus (2019-nCoV), which is responsible for infecting humans. This breakthrough will aid in the development of vaccines and antiviral drugs to combat the spread of the virus. The research was published in Science on February 19. Discuss

Personalized cancer vaccines now possible due to discovery of cancer frameshift neoantigens
Researchers from Arizona State University's Biodesign Institute demonstrated experimental proof-of-concept that cancer mutations produce individual neoantigens, or newly formed antigens, and can be used for cancer vaccines. The new paper published in Scientific Reports on October 2, shows that neoantigens can be used to protect against cancer. Discuss

New synthetic vaccine fights infectious disease with assistance from the data cloud
A new synthetic vaccine developed by researchers at the University of Bristol and the French National Centre for Scientific Research can be stored at warmer temperatures due to an engineered scaffold design. The details of the Chikungunya vaccine candidate are published in Science Advances on September 25. Discuss

Vaccine in development against hypervirulent Klebsiella
Concerns arising over the development of hypervirulent strains of Klebsiella pneumoniae have led researchers to develop an entirely new vaccine to protect against the gram-negative bacteria. A team of researchers at Washington University School of Medicine in St. Louis and VaxNewMo (a startup based in St. Louis) designed the vaccine by genetically manipulating E. coli. The details of the prototype designed were published in the Proceedings of the National Academy of Sciences on August 27th. Discuss

Thermally stable TB vaccine may now be possible thanks to an innovative new process
Researchers at the University of Bath have developed a process that protects vaccines from heat damage by trapping them in silica cages. The results were published in Scientific Reports on August 8, 2019. Using a leading candidate in the development on new vaccines, Ag85b in conjunction with adjuvant Sbi-Ag85b, thermal stability of tested using a novel process called ensilication. Discuss

Structure-based vaccine design may help save the lives of infants and children
A new experimental vaccine, utilizing structure-based design, shows promise in a phase I clinical trial. The vaccine will protect against respiratory syncytial virus (RSV), a leading cause of infectious disease deaths in infants. Researchers at the University of Texas at Austin published findings on Aug 2, 2019 in Science stating that one dose elicited increases in RSV-neutralizing antibodies over several months. Discuss

Conferences

2nd Annual Cell Therapy Bioprocessing Conference
June 25-26
Boston, Massachusetts United States

BioProcess International Europe
July 13-16
Amsterdam, Noord-Holland Netherlands

Bioprocess International West
August 10-13
Santa Clara, California United States

BioProcess International
September 21-24
Boston, Massachusetts United States

Japan Analytical & Scientific Instruments Show (JASIS)
November 11-13
Chiba, Chiba Japan

More Conferences »»

Topic	Replies / Views	Last Update
General Discussion

Open science for the modern scientific community by LMoraes	3 / 53	More than 3 days ago by The Mets
https://academic.oup.com/ve/pages/coronavirus-evolution by Michael	0 / 14	More than 3 days ago by Michael
PopSci Hails Impossible Burger 2.0 as Most Important Engineering Innovation in 2019 by Mahesh Gupta	0 / 8	More than 3 days ago by Mahesh Gupta
Engineered Bacteria Produces BeeFree Honey by Mahesh Gupta	0 / 11	More than 3 days ago by Mahesh Gupta
Consumers' Preference to Buy Unlabeled Produce Increases after Exposure to GMO-labeled Pro by Mahesh Gupta	0 / 14	More than 3 days ago by Mahesh Gupta
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