Pfizer, Thermo Fisher Scientific collaborate to broaden access to NGS testing in underserved countries
Pfizer and Thermo Fisher Scientific on Tuesday announced they have entered into a collaboration agreement to help increase local access to next-generation sequencing (NGS)-based testing for lung and breast cancer patients in more than 30 countries. Read More
An unprecedented view of gene regulation
Massachusetts Institute of Technology (MIT) engineers have developed a technique to analyze the organization of the genome at a resolution 100 times higher than was previously possible. Read More
Artificial genetic sequences improve performance of deep neural networks
Researchers have generated artificial genetic sequences to improve the ability of deep neural networks (DNNs) to predict the rules of DNA regulation. Read More
New STING-seq approach pinpoints disease-causing genetic variants
Researchers are combining genome-wide association studies, CRISPR, and single-cell sequencing to discover causal variants and genetic mechanisms for blood cell traits. Their approach, dubbed STING-seq, published Thursday in Science, connects genetic variants to human traits and health, potentially helping to identify drug targets for genetic diseases. Read More
Getting to know the Association of Biomolecular Resource Facilities (ABRF)
The Association of Biomolecular Resource Facilities (ABRF) will hold its Annual Meeting May 7 to May 10 in Boston. ABRF is a membership organization that brings together Core facilities across the U.S. and supports more than 2,400 members at over 400 institutions including organizations in government, academia, research, industry, and commercial settings. Over 50% of its members define their area of professional responsibility as either genomics or core administration. Read More
Gene variant map helps diagnose hereditary diabetes
University of Copenhagen researchers are using high-throughput experiments to explore connections between inherited diseases and a specific gene called GCK. The study, published April 26 in Genome Biology, may help provide better diagnoses of hereditary diabetes and other diseases. Read More
Bio-Techne fiscal Q3 sales rise 1% on strength in cell therapy, prostate test products
Bio-Techne on Wednesday reported fiscal third-quarter sales of $294.1 million, up 1% compared to $290.4 million in the prior-year quarter and short of analysts’ average estimate of $296.7 million. Read More
Viral peptides improve CRISPR-Cas gene editing to expand cell therapy applications
Scientists have used viral peptides to get CRISPR-Cas gene editing molecules into cells more efficiently and with minimal toxicity, suggesting the method can improve the production of cell and gene therapies. Read More
Researchers modify lentivirus to enable targeted delivery of muscle disease gene therapy
Researchers have created a lentiviral gene therapy vector capable of targeting muscle cells to treat the rare disease Duchenne muscular dystrophy (DMD) in mice. Read More
Unique membrane protein stops viral infection in bacteria
University of Rochester Medical Center (URMC) researchers revealed a previously unrecognized player in the CRISPR system: a membrane protein that enhances antiviral defense. The study, published Thursday in Science, broadens the current understanding of CRISPR’s complexities. Read More
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