Genomics
Shortage of RNA extraction kits threatens coronavirus testing
The weak link in the U.S. response to diagnostic testing for the novel coronavirus SARS-CoV-2 could be a shortage of RNA extraction kits. Fortunately, suppliers of RNA purification kits are working overtime to get more kits into circulation, according to Alice Kan of Strategic Directions International.  Discuss
Bacteria survive by possessing multiple genes to uptake the same amino acid
Researchers have long known that the uptake systems in clonal cells can differ based on their environments. Scientists reported their observations of this amino acid uptake pathway in bacteria for the first time in a new study published March 5 in Nature Communications.  Discuss
Zigzag DNA provides insight into chromosome organization
New Z-loops -- DNA folded into a zigzag structure and guided by essential condensin proteins -- have been caught on camera for the first time. The results of the study provide insight into the organization of chromosomes and were published in Nature on March 4.  Discuss
New NIH study pinpoints how coronavirus attacks cells
The continued spread of the novel 2019 coronavirus, known as SARS-CoV-2, around the world has raised the need for a test to rapidly and efficiently screen coronaviruses to monitor rapid changes and determine how they function. Findings from ongoing U.S. National Institutes of Health (NIH) research, published in Nature Microbiology on February 24, offer new tools in the fight.  Discuss
Phages containing huge amounts of DNA are found around the globe
An inventory of over 350 DNA sequences from phage genomes revealed that these genomes can be over 200,000 base pairs in length and found the largest phage genome ever described at 735,000 base pairs in length. The report published in Nature on February 12, evaluated the prevalence, diversity and ecosystem distribution of phages with large genomes.  Discuss
Genomics sheds light on the life history of cancers
As part of a special collection of papers on pan-cancer analysis of whole genomes published online by Nature on February 6, an international group of scientists analyzed over 2,500 unique cancer genomes to shed light on the life history of cancer mutations and how cancer tumors evolve -- even before they are diagnosed.  Discuss
Chinese researchers mobilize to classify 2019-nCoV
In response to a recent outbreak of the novel coronavirus (2019-CoV), scientists in China have uncovered genetic similarities with severe acute respiratory syndrome (SARS) coronaviruses by analyzing patient samples from the source of the outbreak. Their findings provide crucial evidence that will aid in the classification and identification of 2019-CoV, according to a new report published in Nature on February 3.  Discuss
Institut Pasteur reveals how it sequenced the coronavirus
On January 30, the Institut Pasteur became the first European institution to sequence the novel coronavirus (2019-nCoV) since the outbreak began in December 2019. Institut Pasteur researchers used a unique sequencing platform to confirm the presence of 2019-nCoV in three samples from suspected cases in France.  Discuss
NGS of China coronavirus shows bat origins, intermediate host
Next-generation sequencing (NGS) of 10 genomes of novel coronavirus (2019-nCoV) from nine patients in China demonstrated that the virus is closely related to two coronaviruses that originated in bats, but that an intermediate host may be responsible for the spread to humans, according to a study published in Lancet on January 29, 2020.  Discuss
Enrichment NGS emerges as surveillance tool for coronavirus
As the coronavirus continues to grow as a global health concern, researchers urgently seek efficient methods to predict and mitigate emerging coronavirus strains. An international team of researchers believes that targeted next-generation sequencing (NGS) may be a valuable tool for monitoring both current and future outbreaks of coronavirus originated from bats.  Discuss
Conferences
2nd Annual Cell Therapy Bioprocessing Conference
June 25-26
Boston, Massachusetts United States
BioProcess International Europe
July 13-16
Amsterdam, Noord-Holland Netherlands
Bioprocess International West
August 10-13
Santa Clara, California United States
BioProcess International
September 21-24
Boston, Massachusetts United States
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