Genomics
Bacteria survive by possessing multiple genes to uptake the same amino acid
Researchers have long known that the uptake systems in clonal cells can differ based on their environments. Scientists reported their observations of this amino acid uptake pathway in bacteria for the first time in a new study published March 5 in Nature Communications.  Discuss
Zigzag DNA provides insight into chromosome organization
New Z-loops -- DNA folded into a zigzag structure and guided by essential condensin proteins -- have been caught on camera for the first time. The results of the study provide insight into the organization of chromosomes and were published in Nature on March 4.  Discuss
New coronavirus puts focus on the science of naming new viruses
What's in a name? Possibly a lot, when it comes to determining how to name new virus species based on genetic characteristics. The initial confusion over the naming of the novel coronavirus indicates that the scientific community still has work to do when defining the proper taxonomy of viruses, according to an article published in Nature Microbiology on March 2.  Discuss
Biopharma processing market shows early indicators of strong 2020
The biopharmaceutical processing market shows early indicators of strong 2020, according to our partners Strategic Directions International and Kalorama Information, which are developing an upcoming report on the sector.  Discuss
Glia-to-neuron conversion gene therapy can treat Huntington's disease
Using adeno-associated virus technology, researchers have developed a novel gene therapy that can regenerate functional neurons in mouse models of Huntington's disease. The work was published in Nature Communications on February 27.  Discuss
Extra copies of chromosomes can be good or bad
Researchers are developing human cell lines to explore how extra copies of chromosomes can enhance the metastasis and invasiveness of cancer cells. They explained their methodology in a study published in Developmental Cell on February 24.  Discuss
New NIH study pinpoints how coronavirus attacks cells
The continued spread of the novel 2019 coronavirus, known as SARS-CoV-2, around the world has raised the need for a test to rapidly and efficiently screen coronaviruses to monitor rapid changes and determine how they function. Findings from ongoing U.S. National Institutes of Health (NIH) research, published in Nature Microbiology on February 24, offer new tools in the fight.  Discuss
Genomic landscape of osteosarcomas reveals why immunotherapy may not be effective
Immune profiling of osteosarcoma has revealed why immune checkpoint inhibitors might not be an effective treatment option for patients with this rare type of cancer, according to new research published online February 21 in Nature Communications.  Discuss
Communication of cancer cells analyzed with organoids and novel cytometry
A new technique using organoids, self-organizing 3D tissue models, can decipher how individual cancer cells communicate with each other and the unique signals they create. This research, published in Nature Methods on February 17, could be used to help develop personalized cancer treatments in the future.  Discuss
Genetically engineered probiotics successfully deliver immunotherapies
A new technology enables genetically engineered probiotic bacteria to be used as an efficacious, stable, and safe platform to deliver immunotherapies directly into a variety of tumors in just a single dose. The research was published online on February 12 in Science Translational Medicine.  Discuss
Conferences
2nd Annual Cell Therapy Bioprocessing Conference
June 25-26
Boston, Massachusetts United States
BioProcess International Europe
July 13-16
Amsterdam, Noord-Holland Netherlands
Bioprocess International West
August 10-13
Santa Clara, California United States
BioProcess International
September 21-24
Boston, Massachusetts United States
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