Genomics
DNA 'origami' informs coronavirus vaccine design
Strategically folded DNA arranged to mimic viral antigens -- known as DNA "origami" -- may produce strong immune responses, according to a June 29 report in Nature Nanotechnology. Researchers are now working on adapting this approach for the development of a vaccine against SARS-CoV-2.  Discuss
Innovations in synthetic chemistry help identify new cancer therapies
The pathway to discovering and developing cancer therapies is not always linear, but well-designed models incorporating smart chemical innovations can provide elegant solutions to treatments for some of the most difficult cancers. Some of these efforts were shared on June 22 during the American Association for Cancer Research 2020 virtual annual meeting II.  Discuss
From DNA to precision medicine, researchers discuss breakthroughs in cancer research
From the use of novel technologies such as machine learning and CRISPR, to gaining a deeper understanding of the genetic and molecular drivers of cancer, researchers from around the globe shared their progress with the cancer research community on June 22 at the opening plenary session of the American Association for Cancer Research 2020 virtual annual meeting II.  Discuss
Spell-check gene editing corrects hearing loss in mice
Using a new genetic engineering technique called base editing, researchers restored genetic hearing loss in mice with a recessive point mutation. The research was published by a group from Boston Children's Hospital, the Broad Institute of the Massachusetts Institute of Technology, and Harvard University in Science Translational Medicine on June 3.  Discuss
COVID-19: A double-edged sword for the pharma industry
The COVID-19 pandemic is causing major disruptions to pharmaceutical R&D activities, despite the pressing need for treatments and diagnostics for the novel coronavirus. In a new article, Ivan Gandayuwana of Strategic Directions International examines the multiple impacts COVID-19 is having on pharma.  Discuss
Experts discuss promising strategies for tackling SARS-CoV-2
What's the best strategy for developing treatments for the SARS-CoV-2 virus? The most promising approaches for a rapid response are antivirals and gene therapy, according to a new review article published April 24 in Frontiers in Microbiology.  Discuss
Directed evolution shows promise in reducing drug discovery times
A research collaboration between scientists at the University of Leeds and AstraZeneca resulted in the development of a technique that can significantly reduce the discovery time for possible new antibody-based therapies. The approach, published in Nature Communications on April 14, shows how protein fragments can be screened for susceptibility to aggregation in early drug discovery.  Discuss
Researchers bait viruses with chemically designed structures
A new therapeutic approach for suppressing seasonal influenza that involves synthetic phage shells that interfere with pathogen adhesion is immediately being tested for use on coronaviruses in response to the global COVID-19 pandemic. The research findings were published in Nature Nanotechnology on March 30.  Discuss
Scientists alter cell function with genetic engineering, polymer science
A new method called genetically targeted chemical assembly (GTCA) has demonstrated the ability to build artificial structures within the body to carry out unique functions. The research, presented in the latest edition of Science, provides compelling evidence for GTCA's ability to modify cell function with bioengineering tools.  Discuss
Biopharma processing market shows early indicators of strong 2020
The biopharmaceutical processing market shows early indicators of strong 2020, according to our partners Strategic Directions International and Kalorama Information, which are developing an upcoming report on the sector.  Discuss
Conferences
BioProcess International Europe
July 13-17
Central European Time Zone (CET) Netherlands
2020 ACCP Annual Meeting
September 20-22
Bethesda, Maryland United States
Bioprocess International West
September 21-24
Eastern Standard Time Zone (EST) United States
General Discussion
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