In an attempt to combat bacterial infections, Locus Biosciences is developing bacteriophage therapies that deliver CRISPR-Cas3 machinery directly to specific, targeted pathogens to obliterate them. Locus CEO Paul Garofolo discusses the company's technology and recent updates with The ScienceBoard.net. Discuss
Two groups of researchers have developed unique approaches to overcome the limitations of delivery of gene editing therapeutics. In a pair of new papers, researchers describe methods for more efficient and safe delivery of CRISPR components to targeted cells and tissues. Discuss
A new digital microfluidic technique allows researchers to connect physical cell properties with the molecular makeup of individual cells. This new approach, published in Nature Communications on November 11, will enable a deeper study of stem cells and other rare cell types for therapeutic development. Discuss
Gene therapies offer great benefits to patients but could strain healthcare budgets and exacerbate existing treatment inequities in Canada, according to an expert panel that was commissioned to write a report by the Council of Canadian Academies. Discuss
Researchers have identified a molecule that permits growth of cancers such as leukemia by silencing certain host genes. The results, published in Nature Genetics on November 2, challenge the current understanding of epigenetic control during tumor development. Discuss
A new CRISPR tool utilizes Cas3 to remove larger than normal stretches of DNA both quickly and accurately. The tool, described in an October 19 article in Nature Methods, could help fill a void in current gene editing capabilities. Discuss
Developing well-characterized adeno-associated viral vectors (AAVs) is a significant obstacle for the biomanufacturing industry. A group of analytical researchers is trying to overcome this challenge by developing novel analytical methodology specifically designed for AAVs. Discuss
Gene therapies hold extremely exciting promise for meeting the unmet needs of many individuals with genetic diseases, as discussed in a session of the second annual American Society of Gene & Cell Therapy Policy Summit on September 24. Discuss
With a focus on science and society, the American Society of Gene & Cell Therapy Policy Summit commenced on September 24. The ensuing discussion revealed how far science has advanced in a short period of time, and how the scientific community is rising to the challenge of gaining public buy-in for gene therapy. Discuss
A new technique will help scientists choose the best available gene editing option for any given indication, making CRISPR technology safer, cheaper, and more effective. The tool is outlined in a September 7 article in Nature Biotechnology. Discuss
Conferences
2020 AACC Annual Scientific Meeting & Clinical Lab Expo
December 13-17
Online
December 13-17
Online
Society for Laboratory Automation and Screening (SLAS) 2021
January 23-27, 2021
Online
January 23-27, 2021
Online
Festival of Genomics & Biodata
January 28-29, 2021
London, Greater London United Kingdom
January 28-29, 2021
London, Greater London United Kingdom
4th Annual Cell & Gene Therapy Innovation Leaders Summit 2021 Visualising The Future
February 1-3, 2021
Berlin, Berlin Germany
February 1-3, 2021
Berlin, Berlin Germany
Lab of the Future USA
May 11-12, 2021
Boston, Massachusetts United States
May 11-12, 2021
Boston, Massachusetts United States
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