Genomics
Cell and gene therapy sector remains strong despite challenges: ARM CEO
The cell and gene therapy sector is “quite strong” despite the regulatory, investment, and manufacturing challenges facing the industry, according to Janet Lambert, CEO of the Alliance for Regenerative Medicine (ARM). Lambert spoke with ScienceBoard.net about developments in the industry. Read More
Beta cell gene deletion stops type 1 diabetes in mice, suggesting new way to prevent disease
Deleting a proinflammatory gene in the beta cells of pre-diabetic mice stops the development of type 1 diabetes, pointing to a potential way to prevent the condition, according to a study published on June 28 in the journal Cell Reports. Read More
Mammoth Biosciences looks to build next-generation CRISPR toolbox
This month marks the 10th anniversary of the development of CRISPR as a genome-editing tool. While the technology is fairly new, it has made major strides over the past decade, said Mammoth Biosciences co-founder and CEO Trevor Martin in an interview with ScienceBoard.net. Read More
Meeting on the Med opens with new data and eyes on the money
BARCELONA, SPAIN -- The Cell & Gene Meeting on the Med conference kicked off on April 20 as speakers assessed the current state of the cell and gene therapy sector and explored payment strategies for advanced therapies across the European Union. Read More
Nivolumab/chemo combo will change lung cancer care
A new study that pairs neoadjuvant nivolumab with chemotherapy for patients with nonsmall cell lung cancer has the potential to revolutionize treatment, according to one expert. The research was presented April 11 at the American Association for Cancer Research 2022 meeting and published simultaneously in the New England Journal of Medicine. Read More
CAR T-cells show preliminary efficacy, safety as solid-tumor treatment
Researchers presented phase I/II preliminary clinical trial data demonstrating the safety and efficacy of a new CAR T-cell therapy that can be used as either a monotherapy or a combination therapy to treat Claudin 6-positive solid tumors. The findings were presented at the American Association for Cancer Research Annual Meeting 2022 in New Orleans. Read More
CRISPR technique may lead to hypoallergenic cats
Love cats but have allergies? Rejoice! Scientists have demonstrated that CRISPR gene editing of the cat allergen, Felis domesticus allergen I, could bring relief to those with cat allergies, according to a proof-of-concept study published online in the CRISPR Journal. Read More
Biomedical innovations bring hope to patients with musculoskeletal diseases
Geistlich Biomaterials Italia, Santhera Pharmaceuticals, and Sarepta Therapeutics have entered into a series of collaborations to develop innovative strategies for treating musculoskeletal diseases, ranging from gene therapy to regenerative medicine, according to a recent report in Cell and Gene Therapy Business Outlook, a sister publication of ScienceBoard. Read More
Bacteria don invisibility cloak to fight cancer
Using bacteria to target tumors is a promising avenue for developing new treatments, although the risk of severe side effects is holding back clinical trials. Now, in a new study published on March 17 in Nature Biotechnology, researchers have developed a way to reversibly hide the microbes from the immune system, providing control over their growth. Read More
Berkeley Lab offers CRAGE kit for genome engineering
Lawrence Berkeley National Laboratory (Berkeley Lab) is offering a trial kit for its chassis-independent, recombinase-assisted, genome engineering (CRAGE) tool. Read More
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