Genomics
Reanalysis of old data reveals overlooked liver gene therapy vector with better properties
Rational design and directed evolution have created an adeno-associated virus (AAV) capsid that is better at targeting the liver, setting the stage for its use as a gene therapy vector. Read More
Dialing down activity of Cas enzyme improves safety of CRISPR gene editing in mice
Scientists have modified the synthetic guide RNA (gRNA) that enables CRISPR-Cas gene editing to make the process safer for use in humans. Read More
CRISPR/Cas9 mouse model reveals cellular function changes that drive rare disease
A CRISPR/Cas9 mouse model has shown how mutations that cause a rare disease affect cellular function, shedding light on how to monitor and treat the condition in the process. Read More
At SLAS 2023, companies showcase, launch advanced automation and screening technologies
At the Society for Laboratory Automation and Screening (SLAS) 2023 International Conference and Exhibition, being held in San Diego from February 25 to March 1, numerous firms have announced that they are showcasing emerging technologies for advanced life science applications. Read More
Beckman Coulter, Sciex collaborate on high-throughput screening workflows
Life science analytical technologies company Sciex on Monday announced a collaboration with Beckman Coulter Life Sciences to provide comprehensive workflows for high-throughput screening; high-throughput absorption, distribution, metabolism, and excretion (HT-ADME); and synthetic biology studies. Read More
Algorithm predicts success of next-generation CRISPR edits, advancing push to treat genetic diseases
A machine learning algorithm has predicted the chances of successfully inserting a gene-edited sequence of DNA into a cell using a next-generation CRISPR-Cas9 approach. Read More
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