Genomics
Companion diagnostics survive COVID-19 with small nick
The COVID-19 crisis has had a slightly negative, but not critical, impact on the market for companion diagnostics, according to a new market report from market research firm Kalorama Information.  Discuss
Machine learning helps identify antimicrobial-resistant bacteria
A new graphical user interface-driven, machine learning-based approach has successfully identified antimicrobial resistance genes for gram-positive and -negative bacteria. This work, presented in Scientific Reports on July 3, may make it easier to identify deadly antimicrobial-resistant bacteria.  Discuss
Scientists urge that surveillance of a new SARS-CoV-2 variant is necessary
A SARS-CoV-2 variant carrying an amino acid change, D614G, in the spike protein has become the predominant form of the virus in the current global pandemic. A recent publication in Cell advocated for viral surveillance to aid in the development of immunological interventions.  Discuss
DNA 'origami' informs coronavirus vaccine design
Strategically folded DNA arranged to mimic viral antigens -- known as DNA "origami" -- may produce strong immune responses, according to a June 29 report in Nature Nanotechnology. Researchers are now working on adapting this approach for the development of a vaccine against SARS-CoV-2.  Discuss
Next-generation sequencing reveals inherited mutations in young cancer patients
Researchers advocated for increased genomic surveillance in younger adult cancer patients with tumors that typically strike later in life, in a study presented at the American Association for Cancer Research 2020 virtual meeting, held June 22 to 24.  Discuss
From DNA to precision medicine, researchers discuss breakthroughs in cancer research
From the use of novel technologies such as machine learning and CRISPR, to gaining a deeper understanding of the genetic and molecular drivers of cancer, researchers from around the globe shared their progress with the cancer research community on June 22 at the opening plenary session of the American Association for Cancer Research 2020 virtual annual meeting II.  Discuss
Some viruses may steal host genes to form beneficial hybrid proteins
Certain types of RNA viruses may be capable of using host RNA to expand their own genetic repertoire, according to a new study published in Cell on June 18. This mechanism may enable viruses to overcome the limitations of small genomes and more effectively infect host cells.  Discuss
NIH researchers investigate virulence of SARS-CoV-2 virus
What makes the SARS-CoV-2 virus so virulent? Researchers from the U.S. National Institutes of Health (NIH) analyzed the genomics of the virus -- and compared it to other coronaviruses -- in a June 10 article in the Proceedings of the National Academy of Sciences.  Discuss
Spell-check gene editing corrects hearing loss in mice
Using a new genetic engineering technique called base editing, researchers restored genetic hearing loss in mice with a recessive point mutation. The research was published by a group from Boston Children's Hospital, the Broad Institute of the Massachusetts Institute of Technology, and Harvard University in Science Translational Medicine on June 3.  Discuss
Multiple recombination events may have led to SARS-CoV-2 in humans
A team of scientists evaluating how SARS-CoV-2 jumped to humans found that several genetic recombination events made it especially well-suited to infect humans, according to a study published in Science Advances on May 29.  Discuss
Conferences
BioProcess International Europe
July 13-17
Central European Time Zone (CET) Netherlands
2020 ACCP Annual Meeting
September 20-22
Bethesda, Maryland United States
Bioprocess International West
September 21-24
Eastern Standard Time Zone (EST) United States
General Discussion
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