Genomics
Cell and gene therapy sector remains strong despite challenges: ARM CEO
The cell and gene therapy sector is “quite strong” despite the regulatory, investment, and manufacturing challenges facing the industry, according to Janet Lambert, CEO of the Alliance for Regenerative Medicine (ARM). Lambert spoke with ScienceBoard.net about developments in the industry. Read More
Machine learning model opens door to real-time detection of cell therapy contamination
Researchers at the Massachusetts Institute of Technology’s Singapore site have developed a new way to detect adventitious microbial contamination in mesenchymal stromal cell cultures. By using machine learning to predict if a culture is contaminated in near real-time, the approach could enable testing to take place during the production of cell therapy products. Read More
Tokyo team challenges 10x Genomics with new single-cell RNA sequencing method
Researchers have developed a single-cell RNA sequencing method that is designed to tackle the cell sampling bias of existing techniques and deliver high-precision data, according to a paper published on June 27 in Nature’s Communications Biology journal. Read More
Mammoth Biosciences looks to build next-generation CRISPR toolbox
This month marks the 10th anniversary of the development of CRISPR as a genome-editing tool. While the technology is fairly new, it has made major strides over the past decade, said Mammoth Biosciences co-founder and CEO Trevor Martin in an interview with ScienceBoard.net. Read More
Large-scale WGS of thousands of cancers find previously unreported mutational signatures
Large-scale whole-genome sequencing (WGS) of thousands of cancers has found previously unreported mutational signatures, including tumor-specific rare signatures, according to research published on April 21 in Science. Read More
Illumina brings whole-genome sequencing to German hospital
Illumina has signed an agreement with Hannover Medical School in Germany to assess the use of rapid whole-genome sequencing (rWGS) in critically ill children suspected of having a genetic or rare disease. Read More
Biomedical innovations bring hope to patients with musculoskeletal diseases
Geistlich Biomaterials Italia, Santhera Pharmaceuticals, and Sarepta Therapeutics have entered into a series of collaborations to develop innovative strategies for treating musculoskeletal diseases, ranging from gene therapy to regenerative medicine, according to a recent report in Cell and Gene Therapy Business Outlook, a sister publication of ScienceBoard. Read More
Scientists sequence complete human genome for the 1st time
A team of nearly 100 scientists from the Telomere-to-Telomere Consortium has for the first time unveiled the complete human genome. The findings were published on March 31 in the journal Science. Read More
Gene therapy shows long-term benefits for children with WAS
A lentiviral-based gene therapy treatment for children with Wiskott-Aldrich Syndrome (WAS) has demonstrated long-term benefits, according to research recently published in Nature Medicine. The findings demonstrate a safe alternative to the traditional treatment protocol. Read More
Berkeley Lab offers CRAGE kit for genome engineering
Lawrence Berkeley National Laboratory (Berkeley Lab) is offering a trial kit for its chassis-independent, recombinase-assisted, genome engineering (CRAGE) tool. Read More
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