Genomics
How can the cell and gene therapy field industrialize collaboration?
Adlai Goldberg, the global life sciences digital, social, and commercial innovation leader at Ernst & Young, led a workshop on "Unlocking the Power of Collaboration to Fuel the Industry Transformation for Cell and Gene Therapies" at the 2021 Cell & Gene Meeting on the Mesa. Goldberg called on the cell and gene therapy industry to adopt a mindset of co-collaboration. Read More
5 takeaways from the Cell & Gene Meeting on the Mesa
In this final episode of our coverage from the 2021 Cell & Gene Meeting on the Mesa, hosted by the Alliance for Regenerative Medicine, ScienceBoard.net Editor-in-Chief, Samantha Black, PhD, discusses five takeaways from the event. Read More
New platform identifies best viral vectors for gene therapy
Researchers have developed a novel computational platform that identifies the best viral vector to deliver a gene therapy to its target. The technology, described October 19 in eLife, promises to speed development of adeno-associated virus-mediated gene therapies against vision loss and other disorders. Read More
Bacteria use 'belt and braces' defense system vs. bacteriophages
Researchers have shown how a plasmid in the bacterium Escherichia fergusonii uses a "belt and braces" approach to defend itself against bacteriophages. The breakthrough, published on October 18 in Nucleic Acids Research, could lead to new DNA-targeting biotechnology tools. Read More
Cardiovascular cell, gene therapy leaders discuss nascent field
The emerging field of cardiovascular cell and gene therapies shows great promise to significantly improve clinical outcomes, but it still faces key challenges, according to an October 13 plenary session at the Cell & Gene Meeting on the Mesa. Read More
CGTBO editor comments on trends from Cell & Gene Meeting on the Mesa
Blake Middleton, editor of Cell & Gene Therapy Business Outlook (CGTBO), was joined by Bruce Carlson, senior vice president of publications at Science and Medicine Group, to review the latest developments in therapies from the 2021 Cell  & Gene Meeting on Mesa. Read More
Tecartus becomes 1st CAR T-cell therapy to receive FDA approval for adults with ALL
Tecartus (brexucabtagene autoleucel), a CAR T-cell therapy, has gained approval from the U.S. Food and Drug Administration (FDA) for the treatment of relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL) in adult patients. Read More
Scientists create atlas of mouse brain regions down to single cells
An atlas of the mouse cerebrum and primary motor cortex down to the level of single cells was published in a pair of papers on October 6 in Nature. The research reveals the mammalian brain's organization at an unprecedented level of detail and sheds new light on gene regulatory factors, promising to inform future work on developing targeted therapies for human diseases. Read More
Learning from older drug modalities accelerates viral process development
Andrew Tustian, EngD, director of viral process development at Regeneron Pharmaceuticals, spoke with ScienceBoard.net about accelerating process development for adeno-associated viruses by modifying strategies from older modalities. Read More
New 4D visualization shows epigenetic processes unfold over time
Scientists have developed a new visualization method to construct 4D models of X chromosome inactivation, lending insight into gene expression and opening new pathways to drug treatments for gene-based disorders and diseases. The findings are being published on October 8 in the Proceedings of the National Academy of Sciences of the United States of America. Read More
Conferences
Building Biology in 3D Hybrid Symposium
October 26-27
La Jolla, California United States
Northeast Regional Laboratory Staff and Core Directors (NERLSCD) 2021
November 3-5
Portsmouth, New Hampshire United States
CPhI Worldwide 2021
November 9-11
Milan, Lombardia Italy
Society for Immunotherapy of Cancer (SITC) Annual Meeting
November 10-14
Washington, DC, District of Columbia United States
European Molecular Biology Laboratory (EMBL) Cancer Genomics Conference
November 22-24
Heidelberg Germany
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