Cancer & Disease Research
New algorithm enables comparisons of tumors across patients
Researchers have developed an algorithm that can take either single-cell mass cytometry data or RNA sequencing data, align it, and extract a common denominator for comparing cancer data among patients. The algorithm, called tuMap, was detailed in a study published on October 7 in Cell Systems. Read More
Tecartus becomes 1st CAR T-cell therapy to receive FDA approval for adults with ALL
Tecartus (brexucabtagene autoleucel), a CAR T-cell therapy, has gained approval from the U.S. Food and Drug Administration (FDA) for the treatment of relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL) in adult patients. Read More
GenSight Biologics to highlight gene therapies at Cell & Gene Meeting
French biotechnology firm GenSight Biologics is highlighting its lenadogene neparvovec (Lumevoq) and GS030 gene therapies at the Cell & Gene Meeting on the Mesa in Carlsbad, CA. Read More
Scientists create atlas of mouse brain regions down to single cells
An atlas of the mouse cerebrum and primary motor cortex down to the level of single cells was published in a pair of papers on October 6 in Nature. The research reveals the mammalian brain's organization at an unprecedented level of detail and sheds new light on gene regulatory factors, promising to inform future work on developing targeted therapies for human diseases. Read More
Cytek launches new immunoprofiling assay
Cytek Biosciences has launched a 25-color immunoprofiling assay optimized for its flagship Aurora cell analysis systems. Read More
Scientists tease out role of epithelial cells in lung immunity
A research group has shown how different lung cell roles guide the immune system, according to a study published online on October 5 in Nature Communications. The findings have larger implications in understanding, preventing, and treating multiple lung pathologies, such as those seen in COVID-19. Read More
New 4D visualization shows epigenetic processes unfold over time
Scientists have developed a new visualization method to construct 4D models of X chromosome inactivation, lending insight into gene expression and opening new pathways to drug treatments for gene-based disorders and diseases. The findings are being published on October 8 in the Proceedings of the National Academy of Sciences of the United States of America. Read More
How one company aims to make bedside cell therapies a reality
SQZ Biotech is developing high-throughput technology that can manufacture novel cell therapy products in under 24 hours. Founder and CEO Armon Sharei, PhD, spoke with ScienceBoard.net recently at Biotech Week Boston 2021. Read More
Cancer Cell Map Initiative reveals protein interactions that drive cancer
A research group has mapped previously unknown interactions between proteins that drive cancer, thereby revealing potential new biomarkers and drug targets. The findings were published in a trio of papers in Science on October 1. Read More
Nanoscale sequencer detects 2 cancer-linked RNA base modifications simultaneously
Using a new nanoscale sequencer, a research group has sequenced a microRNA that is a marker for refractory gastrointestinal cancer. The novel method can detect two types of chemical base modifications simultaneously, according to a study published on September 29 in Scientific Reports. Read More
Conferences
Building Biology in 3D Hybrid Symposium
October 26-27
La Jolla, California United States
Northeast Regional Laboratory Staff and Core Directors (NERLSCD) 2021
November 3-5
Portsmouth, New Hampshire United States
CPhI Worldwide 2021
November 9-11
Milan, Lombardia Italy
Society for Immunotherapy of Cancer (SITC) Annual Meeting
November 10-14
Washington, DC, District of Columbia United States
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