Cancer & Disease Research
DNA-based ‘nanotransporters’ deliver precise concentrations of drugs
Canadian researchers have designed and validated a new class of DNA-based drug transporters that are 20,000 times smaller than a human hair, which they contend may improve how cancers and other diseases are treated. Read More
Study provides path for overcoming blood-tumor barrier in treating medulloblastoma
Scientists at Toronto's Hospital for Sick Children have identified a way to reduce the impact of the blood-tumor barrier for treating medulloblastoma, the most common malignant pediatric brain tumor. Read More
EGFR-targeting cell penetrating peptide treats triple-negative breast cancer in mice
A cell penetrating peptide designed to mimic an epidermal growth factor receptor (EGFR) binding domain has induced tumor regression in mice, opening up a new avenue of research into the treatment of triple-negative breast cancer. Read More
Identification of genetic drivers of radiotherapy sensitivity opens door to treatment optimization
Using in silico and experimental profiling platforms, researchers at Northwestern Medicine have identified genetic biomarkers of radiation sensitivity, pointing to opportunities to use genomics to guide radiotherapy treatment for cancer patients. Read More
Bacterium promotes pancreatic cancer growth, adding to evidence of role of tumor microbiome
Virginia Tech researchers have discovered that infection with a bacterium causes pancreatic cells to release cytokines that promote solid tumor growth, potentially helping to guide future therapeutic interventions for cancer treatment. Read More
Antibodies hit drug-resistant cancer cells to improve durability of targeted therapies
Scientists at the Perlmutter Cancer Center at New York University Langone Health have created antibodies designed to target and kill cells that develop resistance to targeted therapies, thereby tackling a barrier to durable anticancer effects. Read More
Mechanistic link between mutation, brain cancer opens up R&D opportunities
Researchers have identified the mechanisms that mean people with a single nucleotide polymorphism have an increased risk of a subtype of brain tumors. Read More
Tumor-promoting mutation linked to suppression of anticancer immune response
Mutations that support the growth of tumor cells may also inhibit T cells, preventing the immune system from responding effectively to emerging cancers, according to Harvard Medical School researchers. Read More
Nanoparticles enhance effect of brain stimulation on stroke recovery in rats
Combining nasally administered nanoparticles and noninvasive brain stimulation improves the recovery of ischemic stroke in rats, according to researchers from Xi’an Jiaotong-Liverpool University and other universities in China. Read More
Biotech licenses drug discovery platform from Harvard, Tufts to study complex CNS diseases
Unravel Biosciences has licensed a drug discovery platform from Harvard University and Tufts University to decode and model complex central nervous system (CNS) diseases. Read More
Glasgow International Health Festival
January 25-26, 2023
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter