Cancer & Disease Research
Targeted therapies can now be more effective with the use of ultrasound technology
Biomedical engineers from the University of Southern California in Los Angeles propose a new method to direct targeted drug release in the body using acoustics. The findings describing how they manipulated ultrasonic waves were published in Applied Physics Letters on November 12, 2019.  Discuss
Novel mitochondrial phenomenon helps explains early neurodegeneration
Northwestern University Feinberg School of Medicine scientists discovered a novel pathway that leads to neurodegeneration in amyotrophic lateral sclerosis (ALS). The study was published in Frontiers in Cellular Neuroscience on November 7. The pathway could explain the development of early stages of neurodegeneration which affects voluntary muscle movement such as walking and talking.  Discuss
Liver-Chip can now determine human-specific toxicities
A group of academic and industry researchers developed new Liver-Chips with four cell types found in the livers of rats, dogs, and humans. The idea was generated at Wyss Institute for Biologically Inspired Engineering at Harvard and then transferred to Emulate Inc., to provide real-time analysis of complex biochemical interactions and enhanced liver toxicity testing.  Discuss
New model uses bioinformatics to identify aggressive breast cancers
Researchers from the University of Bonn propose a new method to determine the prognosis of disease using the patients' tumor tissue. The results were published in Cell Reports on October 29.  Discuss
Immune cells shown to kill MRSA before it enters the body
Neutrophils could be responsible for controlling bacterial numbers of an antibiotic-resistant strain of Staphylococcus aureus (MRSA) on human skin before the bacteria get a chance to invade, according to a new study from Karolinska Institutet published in Cell Reports on October 29.  Discuss
Better flu treatments on the way thanks to the discovery of broadly protective antibodies
Research from the National Institutes of Allergy and Infectious Diseases (NIAID) isolated the antibodies from a person sick with the flu five days after onset. They isolated antibodies that bind to neuraminidase (NA) proteins on the surface of influenza viruses, which provided broad protection against several different strains of influenza both in vitro and in vivo. The researchers provided characterization details in the October 25 issue of Science.  Discuss
New insights into why tumor suppressor proteins go awry in cancer
Researchers from Stowers Institute for Medical Research in Kansas City, MO have identified proteins that are involved in tumor growth and metastasis in many cancers such as breast cancer. The research was published in Science Advances on October 23.  Discuss
Innovations in 3D printing lead to implantable blood vessels
Using bioinks formulated from smooth muscle cells from a human aorta and endothelial cells from an umbilical vein, researchers built a biomimetic blood vessel using 3D printing techniques.  Discuss
Night gardeners: Microglia involved in brain plasticity during sleep
Research from the University of Rochester Medical Center (URMC) suggests that specific immune cells called microglia – which play a crucial role in reorganizing connections between nerve cells, fighting infection, and repairing damage – are primarily active during sleep. The research, conducted on mouse models, was published in Nature Neuroscience on October 21.  Discuss
New study provides molecular insight into how memory changes with age
Researchers from King's College London and The Open University add evidence as to why memory in old age is less flexible than in young adulthood. They published research on October 17, in Current Biology.  Discuss
Conferences
Society for Laboratory Automation and Screening (SLAS) 2020
January 25-29, 2020
San Diego, California United States
American Society for Microbiology (ASM) Biothreats
January 28-30, 2020
Arlington, Virginia United States
Festival of Genomics 2020
January 29-30, 2020
London, Greater London United Kingdom
Medlab Middle East
February 3-6, 2020
Dubai, Dubai United Arab Emirates
Japan Analytical & Scientific Instruments Show (JASIS)
November 11-13, 2020
Chiba, Chiba Japan
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