Cancer & Disease Research
Blocking some T cells may unleash full power of immune system against cancer
Researchers have identified a way to restrict regulatory T-cell activity in tumor cells, which in turn can unleash other immune cells to attack tumors in cancer patients. The research is being published in the August 3 issue of the Proceedings of the National Academy of Sciences. Read More
Bio-Techne launches multiplex spatial genomics assay
Bio-Techne has expanded its RNAscope in situ hybridization technology portfolio with the release of the new RNAscope HiPlex V2 assay for formalin-fixed, paraffin-embedded and fixed and frozen samples for up to 12 targets. Read More
Optogenetic gene therapy provides hope for retinitis pigmentosa patients
Optogenetic therapy bypasses traditional methods of repairing defective photoreceptors in the eye by targeting other retinal cells. Recently, three examples of optogenetic therapeutics under development highlight many of the challenges this type of gene therapy faces for the treatment of a devastating genetic eye disease. Read More
Machine learning predicts if a COVID-19 clinical trial will be successful
Using machine learning, researchers have teased out the underlying factors of success for COVID-19 clinical trials, according to a PLOS One article published on July 12. The analysis showed that drug features and study keywords are the most informative features of COVID-19 trials. Read More
Cells sense repetitive mechanical forces through 'molecular clutch'
A phenomenon known as a "molecular clutch" allows cells in the body to detect the constant mechanical forces they experience, yet the mechanisms for this phenomenon are poorly understood. Now, in a study published recently in Nature Communications, researchers have shown that the frequency of forces can significantly alter the effect on cells. Read More
Google Cloud launches Healthcare Data Engine
Google Cloud announced the preview of Healthcare Data Engine, a tool for healthcare and life sciences organizations that integrates and standardizes data from multiple silos, including medical records, claims, clinical trials, and research data. Read More
Researchers fight drug-resistant bacteria with antibiotic 'Trojan horse'
In the latest chapter of the arms race between scientists and drug-resistant bacteria, scientists have devised an antibiotic-filled "Trojan horse" that penetrates deep into the patient's target tissues before unleashing an antibiotic payload on unsuspecting bacterial invaders. The methodology was described July 19 in eLife. Read More
Cellular programming spurs next-generation cell therapies
Cellular reprogramming of ex vivo cells may offer improvements on first-generation adoptive cell therapies, which have experienced limited clinical success due to complex manufacturing, potential patient rejection, and availability of clinical cell types. Further, in vivo reprogramming may expand on this concept by eliminating the need for manufacture and the risk of immune rejection. Read More
AI drug development startups raised $2.1B in 1st half of 2021
The market for artificial intelligence (AI) in drug development and discovery has been red-hot in recent years. The potential impact that AI can offer to human health and pharmaceutical development has grown in concert with the enabling technologies in computer processing and digitization, as well as new breakthroughs in machine-learning research. Ulrik Kristensen, PhD, of Emersion Insights offers a perspective. Read More
5 ways to improve the biomanufacturing workforce in regenerative medicine
A national survey of regenerative medicine biomanufacturing has revealed gaps in the training of skilled technical workers. The group behind the survey has proposed five steps to improve workforce quality and recently published its recommendations in Stem Cells Translational Medicine. Read More
Conferences
CPhI North America
August 10-12
Philadelphia, Pennsylvania United States
Bioprocessing Summit
August 16-19
Boston, Massachusetts United States
6th Annual CAR-TCR Summit
August 30 - September 2
Online
European Congress of Immunology (ECI) 2021
September 1-4
Belgrade Serbia
Medical Affairs Strategic Summit (MASS)
September 13-15
New Brunswick, New Jersey United States
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