Drug Discovery & Development
Preclinical data on long-acting tuberculosis drug raises hopes for simplified treatment
A long-acting injectable formulation of rifabutin has delivered high plasma concentrations for 16 weeks in mice, resulting in the prevention of tuberculosis and the clearing of the pathogen from the lungs. Read More
First full map of immune system connections unlocks drug discovery opportunities
Researchers have created the first full map of immune system connections showing how immune cells communicate, pointing to ways to modulate the pathways to treat cancer and infectious diseases. Read More
Map of brain changes in Alzheimer’s reveals potential target cell for drug therapies
A National Institute of Aging-backed project has released large-scale cellular and molecular information taken from more than 1.2 million neurons and other brain cells. Read More
Video from AACC: AACC president on Theranos, VALID Act
Dr. Stephen Master, president of the American Association for Clinical Chemistry, provided his thoughts about the main highlights of the 2022 AACC Annual Scientific Meeting & Clinical Lab Expo held this week in Chicago. Read More
Production technique clears barrier to widespread study of intestinal organoids
The aggregation of cells removes variability from the production of small intestinal organoids, clearing a major hurdle to the widespread use of the technologies as a research tool for studying the digestive system, according to a paper published July 28 in Stem Cell Reports. Read More
Lipid in cell membrane of gut bacterium linked to effects on immunity
Researchers have found a lipid in the cell membrane of Akkermansia muciniphila that is responsible for the effect of a gut-resident bacterium on immune processes, with the potential to develop drugs that fight disease by piggybacking on the molecular mechanism. Read More
Scientists discover biomarkers associated with acute, chronic phases of TBI
Arizona State University scientists have provided some of the first detailed view of the molecular and cellular mechanisms behind traumatic brain injury (TBI) as the condition progresses from the acute to the chronic phase. Read More
Analysis of nanoparticles, cancer cells could aid development of nanoparticle-based drugs
Researchers have identified biomarkers that predict whether different types of cancer cells will take up specific nanoparticles, potentially helping to overcome some obstacles to the development of nanoparticle-based drugs. Read More
Lessons from Operation Warp Speed could benefit future drug discovery
What lessons can the biotech industry learn from Operation Warp Speed? In an interview with ScienceBoard.net, Debrah Thompson, PhD, of HTG Molecular Diagnostics, discusses how the success of the COVID-19 vaccine rollout could benefit the drug discovery process going forward. Read More
Repetitive DNA linked to cancer formation in study of replication process
Researchers have discovered that noncoding "junk" DNA could potentially contribute to the development of cancer. Repetitive DNA sequences can cause replication to stall, triggering a response that is similar to the one induced by DNA damage, according to a study published July 19 in Nature Communications. Read More
Conferences
Cell Bio 2022
December 3-7
District of Columbia United States
Glasgow International Health Festival
January 25-26, 2023
Glasgow
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