Drug Discovery & Development
Study offers researchers more reliable way to design effective CELMoD drugs
Scripps Research scientists have discovered a key property needed for a promising new class of cancer-fighting drugs -- known as Cereblon E3 Ligase Modulating Drugs (CELMoDs) -- to work effectively as protein degraders. Read More
Challenge to textbook model of GPCR-mediated signaling opens door to new therapies
University of California, San Diego researchers have challenged the textbook model of how G protein-coupled receptors (GPCRs) mediate signaling in a study that could change how drugs against widely pursued targets are developed, including multiple forms of cancer. Read More
EGFR-targeting cell penetrating peptide treats triple-negative breast cancer in mice
A cell penetrating peptide designed to mimic an epidermal growth factor receptor (EGFR) binding domain has induced tumor regression in mice, opening up a new avenue of research into the treatment of triple-negative breast cancer. Read More
Unlocking New Research Frontiers with Ultra-Sensitive Epigenomics
On-Demand Webinar -- By using a novel in situ strategy that enables unprecedented mapping sensitivity and simplified workflows, CUT&RUN and CUT&Tag are creating a paradigm shift in epigenomics research. Andrea Johnstone, PhD, senior director for product development at EpiCypher, illustrates how these scalable technologies unlock the full potential of epigenomics for next-generation chromatin studies. Read More
GenNext wins $250K grand prize at 2022 BioTools Innovator capstone event
GenNext Technologies, a growth-stage company that enables analysis of protein higher order structure to improve and accelerate drug discovery development, won a $250,000 grand prize at the 2022 BioTools Innovator capstone event on October 13 in Carlsbad, CA. Read More
Stanford team synthesizes anticancer compound currently only sourced from rainforest tree
The synthesis of an anticancer compound in the laboratory by Stanford University researchers has cleared a barrier to the widespread use of a drug candidate that is currently extracted from a single plant species. Read More
Computational screening uncovers potential painkillers without addictive, sedation properties
University of California, San Francisco researchers have used computational screening of 301 million virtual molecules to uncover non-opioid compounds that treated pain without causing sedation in animals, offering lead candidates as an alternative to narcotics. Read More
Biotech licenses drug discovery platform from Harvard, Tufts to study complex CNS diseases
Unravel Biosciences has licensed a drug discovery platform from Harvard University and Tufts University to decode and model complex central nervous system (CNS) diseases. Read More
MIT miniaturizes antenna for wireless operation inside living cells
Massachusetts Institute of Technology (MIT) researchers have created an antenna that can operate inside cells and is compatible with 3D biological systems, with the potential for applications in diagnostics and therapeutics. Read More
Machine learning may accelerate solutions to address protein design challenges
Machine learning can be used to create protein molecules much more accurately and quickly than previously possible, with the potential for developing new treatments and vaccines, according to biologists at the University of Washington School of Medicine. Read More
Conferences
Cell Bio 2022
December 3-7
District of Columbia United States
Glasgow International Health Festival
January 25-26, 2023
Glasgow
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