Drug Discovery & Development
Optogenetic gene therapy provides hope for retinitis pigmentosa patients
Optogenetic therapy bypasses traditional methods of repairing defective photoreceptors in the eye by targeting other retinal cells. Recently, three examples of optogenetic therapeutics under development highlight many of the challenges this type of gene therapy faces for the treatment of a devastating genetic eye disease. Read More
Machine learning predicts if a COVID-19 clinical trial will be successful
Using machine learning, researchers have teased out the underlying factors of success for COVID-19 clinical trials, according to a PLOS One article published on July 12. The analysis showed that drug features and study keywords are the most informative features of COVID-19 trials. Read More
Google Cloud launches Healthcare Data Engine
Google Cloud announced the preview of Healthcare Data Engine, a tool for healthcare and life sciences organizations that integrates and standardizes data from multiple silos, including medical records, claims, clinical trials, and research data. Read More
Cellular programming spurs next-generation cell therapies
Cellular reprogramming of ex vivo cells may offer improvements on first-generation adoptive cell therapies, which have experienced limited clinical success due to complex manufacturing, potential patient rejection, and availability of clinical cell types. Further, in vivo reprogramming may expand on this concept by eliminating the need for manufacture and the risk of immune rejection. Read More
AI drug development startups raised $2.1B in 1st half of 2021
The market for artificial intelligence (AI) in drug development and discovery has been red-hot in recent years. The potential impact that AI can offer to human health and pharmaceutical development has grown in concert with the enabling technologies in computer processing and digitization, as well as new breakthroughs in machine-learning research. Ulrik Kristensen, PhD, of Emersion Insights offers a perspective. Read More
Amazon announces availability of HealthLake cloud repository
Internet services giant Amazon Web Services has announced that its HealthLake cloud-based data repository is now available for use by healthcare and life sciences organizations. Read More
Swiss health data network fuels personalized medicine with data-sharing model
A nationwide data network has been built in Switzerland to support the exchange and reuse of health-related data produced in biomedical and clinical research settings. The strategy, which could serve as a model for how other countries can accelerate the development of personalized medicine, was recently described in an article in JMIR Medical Informatics. Read More
Gene therapy tackles 2 rare childhood diseases 2 different ways
Two new studies point to the efficient use of gene therapy to treat deadly childhood genetic diseases. The first study used direct gene therapy infusion to treat a rare neurodevelopmental disorder, while the second study used prenatal base editing in mouse models as proof of concept for the treatment of genetic diseases. These vastly different approaches show the promise of gene therapy for a variety of devastating diseases. Read More
Future of small-molecule drugs lies in oral formulations
The way forward for small-molecule drug manufacturers is through orally administered products, according to Spiro Rombotis, president and CEO of Cyclacel, who recently spoke with ScienceBoard.net. Read More
Lower lung cancer, melanoma mortality drives down cancer deaths
Declines in mortality due to lung cancer and melanoma have contributed to decreased overall cancer death rates in the U.S. among both men and women and across all racial and ethnic groups, according to an annual report published July 8 in the Journal of the National Cancer Institute. Read More
Conferences
CPhI North America
August 10-12
Philadelphia, Pennsylvania United States
Bioprocessing Summit
August 16-19
Boston, Massachusetts United States
6th Annual CAR-TCR Summit
August 30 - September 2
Online
European Congress of Immunology (ECI) 2021
September 1-4
Belgrade Serbia
Medical Affairs Strategic Summit (MASS)
September 13-15
New Brunswick, New Jersey United States
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