Drug Discovery & Development
Would infecting healthy people with SARS-CoV-2 speed the race to a vaccine?
Could the race to develop a vaccine for SARS-CoV-2 be sped up if researchers were able to study the virus in healthy individuals? And how could such research be conducted safely? These questions were covered in an article published July 1 in the New England Journal of Medicine.  Discuss
FDA issues guidance on COVID-19 vaccine licensure
The U.S. Food and Drug Administration (FDA) has provided new regulatory guidance for developers of vaccines for COVID-19. The guidance lays out the agency's current recommendations regarding the data needed to facilitate clinical development and licensure of vaccines to prevent COVID-19.  Discuss
DNA 'origami' informs coronavirus vaccine design
Strategically folded DNA arranged to mimic viral antigens -- known as DNA "origami" -- may produce strong immune responses, according to a June 29 report in Nature Nanotechnology. Researchers are now working on adapting this approach for the development of a vaccine against SARS-CoV-2.  Discuss
Computer tools shorten development time for SARS-CoV-2 drugs
Computer-based tools are helping researchers find potentially promising candidates for vaccines and treatments for SARS-CoV-2 -- and much more quickly than traditional approaches. Many of these software tools are described in an article published June 24 in Science Advances.  Discuss
Researchers discuss progress toward personalized cancer vaccines
Highly targeted and adaptable platforms allow researchers to develop cancer vaccines for a multitude of different cancer types and even create personalized vaccines for individual cancer patients. Researchers from BioNTech and the Wistar Institute shared exciting developments in cancer vaccines in a methods workshop during the American Association for Cancer Research 2020 virtual annual meeting II.  Discuss
Innovations in synthetic chemistry help identify new cancer therapies
The pathway to discovering and developing cancer therapies is not always linear, but well-designed models incorporating smart chemical innovations can provide elegant solutions to treatments for some of the most difficult cancers. Some of these efforts were shared on June 22 during the American Association for Cancer Research 2020 virtual annual meeting II.  Discuss
Accelerating COVID-19 drug repurposing with computers, organ chips
The U.S. Defense Advanced Research Projects Agency (DARPA) has awarded the Wyss Institute for Biologically Inspired Engineering at Harvard University $16 million to test existing drugs that could be repurposed to prevent or treat COVID-19.  Discuss
Preclinical innovations can speed COVID-19 drug development
Preclinical testing for drug candidates has remained largely unchanged, despite numerous innovations in cell culture techniques. Researchers discussed how these innovations could help speed drug discovery efforts for the COVID-19 pandemic in an article published in Theranostics.  Discuss
SARS-CoV mAb shown to block SARS-CoV-2
Antibodies from recovered SARS-CoV patients appear to block SARS-CoV-2 infectivity and could help in the development of antiviral treatments or vaccines, according to a new study. The findings were published in Nature on May 18.  Discuss
Proteomics provides insights into SARS-CoV-2 infection, potential therapies
Scientists tested a series of compounds for blocking the replication of SARS-CoV-2 using a novel proteomics approach. The method, which helped identify small-molecule drugs that may be effective at treating COVID-19 patients, was published in Nature on May 14.  Discuss
Conferences
BioProcess International Europe
July 13-17
Central European Time Zone (CET) Netherlands
2020 ACCP Annual Meeting
September 20-22
Bethesda, Maryland United States
Bioprocess International West
September 21-24
Eastern Standard Time Zone (EST) United States
General Discussion
Topic Replies / Views Last Update
https://academic.oup.com/ve/pages/coronavirus-evolution
by Michael
0 / 47 More than 3 days ago
by Michael
PopSci Hails Impossible Burger 2.0 as Most Important Engineering Innovation in 2019
by Mahesh Gupta
0 / 14 More than 3 days ago
by Mahesh Gupta
Engineered Bacteria Produces BeeFree Honey
by Mahesh Gupta
0 / 12 More than 3 days ago
by Mahesh Gupta
Consumers' Preference to Buy Unlabeled Produce Increases after Exposure to GMO-labeled Pro
by Mahesh Gupta
0 / 15 More than 3 days ago
by Mahesh Gupta
Super-precise new CRISPR tool could tackle a plethora of genetic diseases
by Mahesh Gupta
0 / 14 More than 3 days ago
by Mahesh Gupta
To see more posts from our community or to share a post of your own, go to our community's forum page.
Connect
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter