Drug Discovery & Development
Precision medicine and molecular understanding of illness
The current era of scientific research is seen by many as a golden age of discovery in genetics, due to rapid progress in numerous areas of science and technology. While healthcare and the pharmaceutical industry traditionally have directed their attention to symptoms rather than underlying causes, the new advances are creating opportunities to better exploit a rapidly expanding mechanistic understanding of disease. The challenges are significant and complex, and the current models of discovery and translation do not provide an obvious path toward an economically sustainable way to integrate data-intensive biology with medicine.  Discuss
New drug target identified in malaria transmission
Australian researchers from the University of Melborne and Griffith University in Queensland have confirmed their findings of a new drug target that blocks the transmission of Plasmodium falciparum in mosquitos. The results were published in Cell Reports on December 17.  Discuss
Adenosine bandages improve tissue repair
Researchers at Duke University have engineered a bandage that captures and holds a pro-healing molecule at the site of a bone break to accelerate and improve the natural healing process. The proof-of-concept experiment was conducted in mice, and the results were published on December 12, in Advanced Materials.  Discuss
Scientists develop a first-of-its-kind in vitro 3D neural tissue model
Researchers from the University of Illinois at Urbana-Champaign have successfully used stem cells to engineer nerve tissues as 3D models of neural networks to study brain function. The work was published in the December 3 edition of the Proceedings of the National Academy of Sciences.  Discuss
Scientists use antibodies to build nanostructures
Researchers from the University of Rome, Tor Vergata demonstrate a new model to control the construction of nanostructures using antibodies. The findings were published in Nature Communications on December 3.  Discuss
New chemistry technique builds more precise nanoparticles
New research published in Nature Communications on November 27th demonstrates a new chemical technique that provides researchers enhanced control over the size and shape of nanoparticles used in drug delivery systems.  Discuss
A discovery of fungi – helping researchers identify new drugs
To address the need to identify new therapeutic targets, researchers at the Hubrecht Institute turned to fungi. The researchers tested secondary metabolites from over 10,000 fungi species and identified 34 biological active compounds with the potential to move to the next step of therapeutic drug development. The research was published in Scientific Reports on November 26.  Discuss
Designer DNA traps dengue virus
Researchers from Rensselear Polytechnic Institute have developed a new approach to trap the dengue virus, a close relative to the Zika virus, in the bloodstream using innovative nanotechnology. The technique was published in Nature Chemistry on November 25.  Discuss
New molecular drivers of Parkinson's disease identified
A group of researchers at the Icahn School of Medicine at Mount Sinai have discovered new molecular drivers of Parkinson's disease (PD) and subsequently determined how they impact the function of genes involved in the disease. This was accomplished using a complex statistical technique called multiscale gene network analysis (MGNA). The results were published in Nature Communications on November 20.  Discuss
Bacterial structures are critical to the development of new antibiotics
A research team from Cornell University have uncovered a unique regulatory mechanism unique to bacterial that may provide crucial insight for antibiotic targeting of pathogens. The work was published in Nature Structural & Molecular Biology on November 18.  Discuss
Conferences
Society for Laboratory Automation and Screening (SLAS) 2020
January 25-29
San Diego, California United States
American Society for Microbiology (ASM) Biothreats
January 28-30
Arlington, Virginia United States
Festival of Genomics 2020
January 29-30
London, Greater London United Kingdom
Medlab Middle East
February 3-6
Dubai, Dubai United Arab Emirates
Japan Analytical & Scientific Instruments Show (JASIS)
November 11-13
Chiba, Chiba Japan
General Discussion
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