Drug Discovery & Development
Unlocking New Research Frontiers with Ultra-Sensitive Epigenomics
On-Demand Webinar -- By using a novel in situ strategy that enables unprecedented mapping sensitivity and simplified workflows, CUT&RUN and CUT&Tag are creating a paradigm shift in epigenomics research. Andrea Johnstone, PhD, senior director for product development at EpiCypher, illustrates how these scalable technologies unlock the full potential of epigenomics for next-generation chromatin studies. Read More
GenNext wins $250K grand prize at 2022 BioTools Innovator capstone event
GenNext Technologies, a growth-stage company that enables analysis of protein higher order structure to improve and accelerate drug discovery development, won a $250,000 grand prize at the 2022 BioTools Innovator capstone event on October 13 in Carlsbad, CA. Read More
Stanford team synthesizes anticancer compound currently only sourced from rainforest tree
The synthesis of an anticancer compound in the laboratory by Stanford University researchers has cleared a barrier to the widespread use of a drug candidate that is currently extracted from a single plant species. Read More
Computational screening uncovers potential painkillers without addictive, sedation properties
University of California, San Francisco researchers have used computational screening of 301 million virtual molecules to uncover non-opioid compounds that treated pain without causing sedation in animals, offering lead candidates as an alternative to narcotics. Read More
Biotech licenses drug discovery platform from Harvard, Tufts to study complex CNS diseases
Unravel Biosciences has licensed a drug discovery platform from Harvard University and Tufts University to decode and model complex central nervous system (CNS) diseases. Read More
MIT miniaturizes antenna for wireless operation inside living cells
Massachusetts Institute of Technology (MIT) researchers have created an antenna that can operate inside cells and is compatible with 3D biological systems, with the potential for applications in diagnostics and therapeutics. Read More
Machine learning may accelerate solutions to address protein design challenges
Machine learning can be used to create protein molecules much more accurately and quickly than previously possible, with the potential for developing new treatments and vaccines, according to biologists at the University of Washington School of Medicine. Read More
MIT team finds limitations of AlphaFold’s AI protein structures in drug discovery
Advances in the modeling of protein-ligand interactions are needed to realize the potential of the artificial intelligence (AI) AlphaFold database of protein structure predictions in drug discovery, according to a new paper from researchers at the Massachusetts Institute of Technology (MIT). Read More
Harvard’s Wyss Institute spins out protein detection technology to create Spear Bio
The Wyss Institute for Biologically Inspired Engineering at Harvard University has licensed technology for detecting proteins in small patient samples to a newly formed startup. Read More
Lupus pill moves to clinical trial in humans after success in mice
Scientists at this week’s fall meeting of the American Chemical Society report they have begun phase II clinical trials of an oral pill containing a compound that in mice, not only prevented lupus-like symptoms, but also reversed signs of organ damage caused by the disease and prevented death. Read More
Conferences
Connect
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter