Drug Discovery & Development
Researchers explore mutations to improve drug design
Drug resistance is a common challenge when designing therapeutics for cancers or diseases originating from bacteria or viruses. Researchers explored how evolution impacted the mutation of these pathogens, and their findings could lead to the development of evolutionarily designed drugs. The results were published March 24 in Cell Reports.  Discuss
Could more sugar-based drugs be on the way?
Researchers from Denmark have developed a new technique to characterize complex sugar molecules in exquisite detail never before achieved, according to a report published on March 20 in Nature Communications. They hope to leverage the new structural information for the development of therapies.  Discuss
Cryo-EM sheds light on ion channel regulation
A long-standing hypothesis about the regulation of ion channels has been confirmed by cryoelectron microscopy (cryo-EM) imaging. The research presented in Nature on March 18 advances the basic understanding of key cellular processes that can be leveraged for a number of therapeutic and research applications.  Discuss
Researchers make sweet music with protein design technique
What does protein design have to do with music theory? A group of researchers from Massachusetts Institute of Technology saw commonalities between the two and designed a technique based on sonification that translates protein structures into musical scores as part of their effort to design new proteins. The details were published in APL Bioengineering on March 17.  Discuss
New biocompatible microparticles created with heat, light
A new simple and scalable protein-processing technique based on temperature-sensitive phase changes creates unique microarchitectures within microparticles for use in drug delivery and other bioengineering applications, according to a study published in Nature Communications on March 12.  Discuss
Chemists develop method to identify protein neighbors
A new technology called µMap uses photocatalysts, molecules that spur a chemical reaction when activated by light, to identify spatial relationships of cell surface proteins. The results are described by scientists from Princeton University and Merck in the March 6 edition of Science.  Discuss
Biopharma processing market shows early indicators of strong 2020
The biopharmaceutical processing market shows early indicators of strong 2020, according to our partners Strategic Directions International and Kalorama Information, which are developing an upcoming report on the sector.  Discuss
From lab to clinic: How AI can help
Clinical trials are an important checkpoint in moving therapies from the lab to the clinic, and artificial intelligence (AI) software can help researchers and clinicians reach their goals in several ways, according to a new article by U.K. market research firm Signify Research.  Discuss
3 reasons the coronavirus outbreak has been so severe
WASHINGTON, DC - Why has the current outbreak of coronavirus been so severe compared with past epidemics of viral respiratory diseases? It has to do with unique characteristics of the coronavirus itself, according to a speaker at a February 26 congressional briefing.  Discuss
Inflammatory attack comes from an unexpected source in rheumatoid arthritis
Researchers have pinpointed immune cells called natural killer cells as an unexpected source of inflammatory proteins that contribute to rheumatoid arthritis. The research was published in the Journal of Experimental Medicine on February 25.  Discuss
Conferences
2020 ACCP Annual Meeting
September 20-22
Bethesda, Maryland United States
Bioprocess International West
September 21-24
Eastern Standard Time Zone (EST) United States
BioProcess International
September 21-24
Eastern Standard Time Zone (EST), Massachusetts United States
General Discussion
Topic Replies / Views Last Update
Childhood vaccines may help protect against COVID-19 mortality
by Ratcatcher
0 / 6 More than 3 days ago
by Ratcatcher
https://academic.oup.com/ve/pages/coronavirus-evolution
by Michael
0 / 49 More than 3 days ago
by Michael
PopSci Hails Impossible Burger 2.0 as Most Important Engineering Innovation in 2019
by Mahesh Gupta
0 / 14 More than 3 days ago
by Mahesh Gupta
Engineered Bacteria Produces BeeFree Honey
by Mahesh Gupta
0 / 13 More than 3 days ago
by Mahesh Gupta
Consumers' Preference to Buy Unlabeled Produce Increases after Exposure to GMO-labeled Pro
by Mahesh Gupta
0 / 15 More than 3 days ago
by Mahesh Gupta
To see more posts from our community or to share a post of your own, go to our community's forum page.
Connect
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter