Proteomics
Cell and gene therapy firms see over $13.6B so far in 2021
Rapid financing activity in the cell and gene therapy industry has exceeded $13 billion in 2021. Over half of this funding is from venture capital and private investments, with over 100 funding deals of this type. Read More
COVID multiomics dataset, portal go online for public use
A new multidimensional dataset for COVID-19 multiomics research has been released to the public, along with a free online research portal for analyzing the data. The COVIDome Explorer and dataset, described recently in Cell Reports, give researchers a way to share data and collaborate in real-time for the clinical management of COVID-19. Read More
Long-read sequencing of circRNA finds autism-linked microexons
Scientists have developed a new laboratory protocol and bioinformatic pipeline using a long-read sequencing platform from Oxford Nanopore Technologies for exploring the composition of circular RNA (circRNA). The technique, published on August 10 in Nature Communications, showed that a group of microexons that had been previously linked to autism are preferentially found in circRNA. Read More
Researchers identify chronic stress gene target in brain
By studying how genes affect receptors in the brain under stress, researchers have discovered new molecular mechanisms behind the function of corticosterone, the stress hormone. The research was published in Nature Communications on August 6. Read More
New sequencing workflow efficiently maps protein-protein interactions
A new tool called protein-protein interaction sequencing (PROPER-seq) allows researchers to map complex networks of proteins within cells of interest without the need for specialized resources, like antibodies or premade gene libraries. The methodology was published in Molecular Cell on August 3. Read More
Blocking some T cells may unleash full power of immune system against cancer
Researchers have identified a way to restrict regulatory T-cell activity in tumor cells, which in turn can unleash other immune cells to attack tumors in cancer patients. The research is being published in the August 3 issue of the Proceedings of the National Academy of Sciences. Read More
Algorithm expands what scientists can uncover from individual cells
A new software tool can help researchers further utilize single-cell RNA sequencing data to learn more about individual cells by incorporating biologically relevant data into the analysis. The machine-learning algorithm, detailed in Genome Research on June 30, can be used to predict which transcription factors are most active in individual cells. Read More
What makes immunotherapies successful in one tumor but not in others?
Researchers have developed a new framework to uncover pathophysiological and molecular features that determine the effectiveness of immunotherapies. The research, published in Nature Communications on June 29, provides an opportunity for improving patient care and gaining a deeper understanding of cancer immunotherapy mechanisms. Read More
A new way to account for evolution in engineered biological systems
A defining characteristic of biology is that life evolves. Traditional biological engineering views an engineered product as a final destination in the design process. However, the authors of a perspective piece published in Nature Communications on June 7 believe that a new perspective is needed for engineering of biological systems -- one that takes into consideration how a biosystem will continue to evolve over time. Read More
Single-cell study discovers how antibody regulators develop in tissue
The development process of immune cells important for establishing long-term immunity has been revealed through detailed single-cell techniques. A new study, published in the journal Science Immunology on May 28, examined extracted tonsils and lymph nodes to establish how human T follicular cells specialize in the body. Read More
Conferences
Cell Bio 2021
December 11-15
San Diego, California United States
Antibody Engineering and Therapeutics
December 13-17
San Diego, California United States
Conferences
Cell Bio 2021
December 11-15
San Diego, California United States
Antibody Engineering and Therapeutics
December 13-17
San Diego, California United States
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