Immunology Sponsored by Beckman Coulter
New model could improve vaccine, immunotherapy design
A new model used to predict the outcomes of pathogen detection systems as a function of innate immunity may lead to more effective cancer immunotherapies and vaccines against existing and novel pathogens, according to results published in Cell Systems on October 27.  Discuss
Who should get the 1st COVID-19 vaccines?
Once a vaccine for SARS-CoV-2 is approved by the U.S. Food and Drug Administration to be administered to the public, who should receive it first, given that its supply will be initially limited? A new perspective published in Science on October 21 fleshes out different COVID-19 vaccine distribution strategies that would ensure optimal protection from the disease under conditions of vaccine scarcity.  Discuss
Can SARS-CoV antibodies be used to develop universal coronavirus vaccines?
Can antibodies developed against SARS-CoV during the 2003 outbreak be used to prevent infection by SARS-CoV-2? In an October 9 study published in Science Advances, researchers analyzed precious serum collected from convalescent SARS-CoV patients to find out.  Discuss
Will mutation of the SARS-CoV-2 virus affect vaccine effectiveness?
What impact will mutation of the SARS-CoV-2 virus have on the effectiveness of COVID-19 vaccines that are in development? In a new study published in NPJ Vaccines on October 8, Australian researchers say they believe that a recent change in the genetic material of the virus shouldn't reduce the effectiveness of vaccines coming to market.  Discuss
Flood of COVID-19 papers allows substandard research to slip through
This year's deluge of COVID-19 research publications has allowed substandard research to be published by academic journals or to be housed on preprint servers, resulting in the retraction of some papers. The chaotic publishing environment has potentially harmful implications for COVID-19 patients during treatment, a leading bioethicist wrote in a brief published in the Journal of Medical Ethics on October 1.  Discuss
COVID-19 concerns may undermine vaccine rates for seasonal flu
Only a third of parents believe that the flu vaccine will be more important this year, and 1 in 7 parents will not vaccinate their child due to concerns about COVID-19, according to the results of a new poll. The poll results underscore concerns that there could be a double impact of seasonal flu and COVID-19 this winter.  Discuss
Passive vaccines with mAbs may be effective for COVID-19
Monoclonal antibodies (mAbs) isolated from the blood of recovered COVID-19 patients -- known colloquially as "convalescent plasma" -- could be potentially useful as therapeutic and prophylactic agents for passive vaccination, assuming their administration does not trigger unwanted side effects. The findings of the new study were published in Cell on September 26.  Discuss
Are people in your state getting vaccinated?
Support for a COVID-19 vaccine continues to wane even as companies report being closer to bringing one to the public. This may not be surprising, considering people in many U.S. states don't get inoculated for other diseases such as polio and the flu.  Discuss
Are T cells more important than antibodies in COVID-19?
A new study stressed the importance of a multilayered, virus-specific immune response for controlling SARS-CoV-2 during acute COVID-19, with an emphasis on the critical nature of T cells over antibodies during the process. The work was published in Cell on September 16.  Discuss
How willing are U.S. adults to accept a COVID-19 vaccine?
A recent online survey of adults residing in the U.S. found that close to 70% of those surveyed would accept a COVID-19 vaccine if one were widely available. The study findings were published in the journal Vaccine on August 20.  Discuss
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