Genomics Sponsored by Nvidia
ESMO recommends use of NGS for advanced cancers
The European Society for Medical Oncology (ESMO) released its first recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers. The guidance was published in the Annals of Oncology on August 25.  Discuss
Genomic mutations can influence disease risk
The reason why some genetically predisposed individuals may or may not develop a disease is rooted in mutations throughout the genome, according to a new study published in Nature Communications on August 20. The researchers explained how this information can be used to improve disease risk estimations in the clinic.  Discuss
SARS-CoV-2 causes immune paralysis in severe cases of COVID-19
The SARS-CoV-2 virus can cause the paralysis of key immune cells as the COVID-19 disease progresses, and this immune paralysis can be the difference between severe and mild cases of COVID-19, according to a study published in Science on August 11.  Discuss
Genetic engineering shows how 'foreign' DNA impacts evolution
A new study has demonstrated that "foreign" DNA -- DNA transferred horizontally into a species from a source other than a parent -- can become functional over time and can impact an organism's evolution and fitness, according to a paper published August 10 in Nature Ecology and Evolution.  Discuss
Microbes shape antibodies prior to infection
Genetic analysis of antibodies reveals how microbes in the intestines impact overall B-cell populations and humoral responses to pathogens. The research was published in Nature on August 5.  Discuss
Human-infecting coronaviruses have lived in bats for decades
Genome sequencing of the SARS-CoV-2 virus has revealed that the type of virus family to which the novel coronavirus belongs most likely first emerged in bats in the late 1960s, according to a new study published in Nature Microbiology on July 28.
Genetic regulation of immune diseases starts at birth
Areas of the human genome may explain the early origins of chronic immune and inflammatory diseases that develop later in life, according to a study published in Nature Communications on July 28.  Discuss
SARS-CoV-2 envelope protein identified as target for antiviral drugs
Comparison of the SARS-CoV-2 genome with other betacoronaviruses can provide useful information on how drugs targeting other coronaviruses may improve outcomes for COVID-19 patients. The analysis was presented in a July 27 Frontiers in Cellular and Infection Microbiology article.  Discuss
Life science instrumentation market adapts to COVID-19
To reflect the new realities of the analytical instrumentation market during the COVID-19 pandemic and in the subsequent pandemic-driven recession, Strategic Directions International, a sister company of The Science Advisory Board, has released its revised edition of the Global Assessment Report.  Discuss
Could COVID-19 end standoff on tests developed in laboratories?
During the COVID-19 pandemic, research and clinical laboratories were working overtime to develop tests that would help them identify and understand SARS-CoV-2, according to Kalorama Information, a sister company of The Science Advisory Board. These lab-developed tests have become an essential component in the fight against the virus.  Discuss
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