Cell Biology
Benchtop capillary electrophoresis opens new doors for sample identification
Sample identification and verification is essential to research that interrogates and compares specific regions of the human genome, called short tandem repeats. Benchtop capillary electrophoresis is a sample identification method that can be easily implemented in research labs for many forensic and research applications. Read More
Multiomics approach profiles molecular characteristics of glioblastoma
A team of more than 40 investigators has created a profile of the genes, proteins, infiltrating cells, and signaling pathways of the deadly brain cancer glioblastoma. The findings could lead to better patient care, according to the authors of a new study published February 11 in Cancer Cell. Read More
Researchers use modified CRISPR tool to manipulate the epigenome
Bioengineers have developed a new way to engineer the human epigenome (chemical changes in the DNA) using a modified CRISPR-Cas9 system to target and activate proteins in the chromosome. This research, published in Nature Communications on February 9, expands on synthetic genome tools. Read More
New synthetic biology approach may improve delivery of programmable medicines
Programmable medicines that can be controlled by synthetic genetic components are not yet a clinical reality. But synthetic components can now be reconfigured so they don't overwhelm host cells, moving the technology a step closer to clinical reality, according to new research published February 8 in Nature Communications. Read More
Researchers innovate drug discovery screening techniques
Researchers from around the globe gathered to discuss innovations in laboratory techniques such as phenotypic profiling and flow cytometry for drug discovery applications at the Society for Laboratory Automation and Screening 2021 virtual meeting. Read More
Protein biosensors show promise for SARS-CoV-2 testing
Scientists have developed biosensors to detect SARS-CoV-2 proteins and antibodies in simulated nasal fluids and human sera, according to a study published in Nature on January 27. The approach promises to be less costly and time-consuming than current COVID-19 testing methods. Read More
Not all genome editing tools are equal: CRISPR vs. TALEN
In recent years, a number of novel genome editing tools have emerged, although not all of these tools are equal in terms of efficiency and accuracy, according to a new study published in Nature Communications on January 27. The study observed different DNA search proteins to identify the specific ways that they find target sequences in the genome. Read More
New discovery could lead to broad-spectrum antivirals
Scientists have identified a key human gene that is required for cells to consume and destroy viruses. The results of the study were published in Nature on December 16 and could point to new treatments to target viral infections, including COVID-19. Read More
Google's DeepMind makes a quantum leap in solving the protein folding problem
Artificial intelligence has made something of a breakthrough in the prediction of protein structures. The results came about as part of the 14th Critical Assessment of Structure Prediction, a friendly contest and conference organized by the Protein Structure Prediction Center with sponsorship from the National Institute of General Medical Sciences, part of the U.S. National Institutes of Health. Read More
Cas9 modification can improve efficiency of gene editing
A modification to CRISPR/Cas9 systems can improve their functionality for gene editing in DNA repair, according to a report published in Nature Communications on November 27. The new Cas9 variant also improves the safety of the system for precision gene editing applications. Read More
Connect
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter