New 'antibody-decorated nanocrystals' target cancer cells
Researchers have bioengineered a metal-organic framework antibody drug delivery system that has the potential to fast-track personalized therapies for cancer and other diseases. The findings were published December 7 in the journal Advanced Materials. Read More
Scientists identify diagnostic gene signature for breast cancer
Researchers have identified a diagnostic signature for genetic mutations and other abnormalities associated with drug resistance and poor outcomes in estrogen receptor-positive metastatic breast cancers. The findings, published on October 28 in Cancer Research, may one day guide personalized treatments for cancer patients. Read More
New algorithm enables comparisons of tumors across patients
Researchers have developed an algorithm that can take either single-cell mass cytometry data or RNA sequencing data, align it, and extract a common denominator for comparing cancer data among patients. The algorithm, called tuMap, was detailed in a study published on October 7 in Cell Systems. Read More
Cancer Cell Map Initiative reveals protein interactions that drive cancer
A research group has mapped previously unknown interactions between proteins that drive cancer, thereby revealing potential new biomarkers and drug targets. The findings were published in a trio of papers in Science on October 1. Read More
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