Cell Biology
Scientists develop a first-of-its-kind in vitro 3D neural tissue model
Researchers from the University of Illinois at Urbana-Champaign have successfully used stem cells to engineer nerve tissues as 3D models of neural networks to study brain function. The work was published in the December 3 edition of the Proceedings of the National Academy of Sciences.  Discuss
Leveraging new technologies to push the boundaries of our knowledge of cell biology
At the American Society of Cell Biology, European Molecular Biology Organization Joint Meeting in Washington, DC from December 7-11, emerging topics and new technologies were discussed and highlighted. Proteomics and genomics seemed to be a focus of the meeting. Many researchers presented novel ideas to incorporate new technologies in these fields to make discoveries in cell biology.
Scientists identify chaperones as potential therapies for Parkinson's disease
Researchers from the University of Basel have identified the malfunctional relationship and master regulatory mechanisms between chaperone proteins and α-Synuclein occurring in Parkinson's disease. The findings were published in Nature on December 4.  Discuss
A discovery of fungi – helping researchers identify new drugs
To address the need to identify new therapeutic targets, researchers at the Hubrecht Institute turned to fungi. The researchers tested secondary metabolites from over 10,000 fungi species and identified 34 biological active compounds with the potential to move to the next step of therapeutic drug development. The research was published in Scientific Reports on November 26.  Discuss
Designer DNA traps dengue virus
Researchers from Rensselear Polytechnic Institute have developed a new approach to trap the dengue virus, a close relative to the Zika virus, in the bloodstream using innovative nanotechnology. The technique was published in Nature Chemistry on November 25.  Discuss
Bacterial structures are critical to the development of new antibiotics
A research team from Cornell University have uncovered a unique regulatory mechanism unique to bacterial that may provide crucial insight for antibiotic targeting of pathogens. The work was published in Nature Structural & Molecular Biology on November 18.  Discuss
New mechanism elucidated for essential molecule-sorting organelle
A new study published in Nature Communications on November 15 suggests a new mechanism by which vesicles are transported out of the Golgi apparatus for the formation and maintenance of endosomes. The work, conducted by researchers from Tokyo University of Science and the Institute of Science and Technology in Austria, changes the paradigm of how materials are sorted and distributed once they enter cells.  Discuss
Genomic breakthrough in malaria research
An international consortium of researchers from the Institute of Cell Biology at the University of Bern and Umeå University in Sweden conducted a genome-wide deletion study to determine genes that are required for malaria parasite transmission. The results were presented in Cell on November 14.  Discuss
Novel mitochondrial phenomenon helps explains early neurodegeneration
Northwestern University Feinberg School of Medicine scientists discovered a novel pathway that leads to neurodegeneration in amyotrophic lateral sclerosis (ALS). The study was published in Frontiers in Cellular Neuroscience on November 7. The pathway could explain the development of early stages of neurodegeneration which affects voluntary muscle movement such as walking and talking.  Discuss
Liver-Chip can now determine human-specific toxicities
A group of academic and industry researchers developed new Liver-Chips with four cell types found in the livers of rats, dogs, and humans. The idea was generated at Wyss Institute for Biologically Inspired Engineering at Harvard and then transferred to Emulate Inc., to provide real-time analysis of complex biochemical interactions and enhanced liver toxicity testing.  Discuss
Conferences
Society for Laboratory Automation and Screening (SLAS) 2020
January 25-29, 2020
San Diego, California United States
American Society for Microbiology (ASM) Biothreats
January 28-30, 2020
Arlington, Virginia United States
Festival of Genomics 2020
January 29-30, 2020
London, Greater London United Kingdom
Medlab Middle East
February 3-6, 2020
Dubai, Dubai United Arab Emirates
Japan Analytical & Scientific Instruments Show (JASIS)
November 11-13, 2020
Chiba, Chiba Japan
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