Immunology
Oncolytic virotherapy, immunotherapy combo shows promise for treatment-resistant cancers
A combination of oncolytic virotherapy, a technique using cancer-fighting viruses, acting in concert with immunotherapy shows promise for treatment-resistant cancers, according to new research. Read More
Localized delivery of IL-2 by drug-producing cells eradicates cancer in mice
Implanting beads loaded with cytokine-producing cells eradicates advanced-stage mesothelioma tumors in mice, according to a study published on August 22 in Clinical Cancer Research. Read More
First full map of immune system connections unlocks drug discovery opportunities
Researchers have created the first full map of immune system connections showing how immune cells communicate, pointing to ways to modulate the pathways to treat cancer and infectious diseases. Read More
Researchers identify T cells that protect against ischemic stroke in mice
University of Pittsburgh neurologists and immunologists have identified a subset of CD8+ regulatory-like T cells (CD8+TRLs) that provide fast-acting and lasting protection against ischemic stroke in mice, offering a potentially novel immunotherapy for stroke in humans. Read More
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