The Science Advisory Board

Sequencing & screening DNA (microarrays, NGS) Synthetic biology

Personalized disease models help to fight pediatric cancers
Researchers at Cedars-Sinai have developed a new rapid technique the genetically modify mice to produce personalized animal models, for example, pediatric glioma. Discuss

Germline genetic testing in breast cancer patients may lead to increased therapy options
Genetic testing for metastatic breast cancer patients may play a key role in identifying additional patients with increased risk and their response to targeted therapies. Discuss

Vaccine in development against hypervirulent Klebsiella
Concerns arising over the development of hypervirulent strains of Klebsiella pneumoniae have led researchers to develop an entirely new vaccine to protect against the gram-negative bacteria. A team of researchers at Washington University School of Medicine in St. Louis and VaxNewMo (a startup based in St. Louis) designed the vaccine by genetically manipulating E. coli. The details of the prototype designed were published in the Proceedings of the National Academy of Sciences on August 27th. Discuss

A novel approach to using CRISPR: curing cystic fibrosis
Researchers are finding innovative ways to utilize CRISPR technology to permanently cure diseases, in this case, cystic fibrosis. A collaboration between the University of Trento in Italy and KU Leuven in Belgium, funded by Fondazione ricerca fibrosi cistica led to the publication of a new study in Nature Communications on August 7, 2019. Discuss

Building proteins from scratch – how AI is helping advance synthetic biology
A new de novo designed protein – degronLOCKR, is the first completely artificial protein switch that operates within cells. LOCKR (short for Latching, Orthogonal Cage/Key pRotein) design and initial practical applications were published in Nature on July 24, 2019. Research was conducted by research teams at UW Medicine Institute for Protein Design and the University of California San Francisco. Discuss

Genome mining has potential uses in synthetic biology and drug discovery
Researchers discovered a cluster of genes in Pseudomonas syringae which infects plants. The results of this research were published in Science on July 19th. However, this natural product produced belongs to a special class of ribosomally synthesized and posttranslationally modified peptides. Discuss

The European Commission pursues open science and why it’s important
Scientists believe that there is a reproducibility crisis in the scientific community where many scientists fail to reproduce experiments, according to a new report by Science | Business in July 2019. Open science is a high priority for the European Commission, with around 70% of all data generated by EU-funded programs being accessible to the public. Discuss

Landmark study explores public understanding of science and trust in scientific and medical professionals
Understanding global perceptions and knowledge of science is of growing interest to the scientific community. Organizations such as 3M, with their State of Science Index Survey and the Wellcome Global Monitor (WGM), from the Wellcome Foundation and Gallup World Poll, explore attitudes towards science and medicine, and also confidence in scientists themselves. Discuss

Leaders in science and engineering publications over the last decade: China and the US
Capturing the attention of policy makers and companies serving the academic research market the countries with the largest number of science and engineering (S&E) articles has significantly evolved between 2007 and 2017. China leads the list in 2017 followed by the US, a reverse from 2007, according to a May report from the NSF’s National Center for Science and Engineering Statistics. Discuss

A convergence of technologies, revolutionizing next-generation sequencing
A new, powerful combination of biochips and next-generation sequencing (NGS) is capable of solving unique and important biological problems, such as single-cell, rare-cell or rare-molecule analysis, which NGS can't do on its own. Discuss

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Conferences

Microbiology Society Annual Conference 2020
March 30 - April 3
Edinburgh, Edinburgh, City of United Kingdom

Experimental Biology 2020
April 4
San Diego, California United States

BioProcess International Europe
April 28 - May 1
Amsterdam, Noord-Holland Netherlands

Lab of the Future USA
May 19-20
Boston, Massachusetts United States

2nd Annual Cell Therapy Bioprocessing Conference
June 25-26
Boston, Massachusetts United States

More Conferences »»

Topic	Replies / Views	Last Update
General Discussion

Open science for the modern scientific community by LMoraes	3 / 51	More than 3 days ago by The Mets
https://academic.oup.com/ve/pages/coronavirus-evolution by Michael	0 / 14	More than 3 days ago by Michael
PopSci Hails Impossible Burger 2.0 as Most Important Engineering Innovation in 2019 by Mahesh Gupta	0 / 8	More than 3 days ago by Mahesh Gupta
Engineered Bacteria Produces BeeFree Honey by Mahesh Gupta	0 / 11	More than 3 days ago by Mahesh Gupta
Consumers' Preference to Buy Unlabeled Produce Increases after Exposure to GMO-labeled Pro by Mahesh Gupta	0 / 14	More than 3 days ago by Mahesh Gupta
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