NIH awards Ky. center $20.5M to study Alzheimer’s, dementia
September 6, 2022 -- The National Institute of Aging, a part of the National Institutes of Health (NIH), awarded a team of researchers at the University of Kentucky’s Sanders-Brown Center on Aging a $20.5 million grant to study Alzheimer’s disease and other related dementias. Read More
Landmark study sequences most childhood cancer samples from single cancer type ever
September 2, 2022 -- Scientists from St. Jude Children’s Research Hospital have created a roadmap of the genetic mutations present in the most common childhood cancer, acute lymphoblastic leukemia, claiming they have sequenced the most childhood cancer samples from a single cancer type ever. Read More
Protein RAF1 structure revealed, opens door to new lung cancer drugs
September 2, 2022 -- Using cryo-electron microscopy, researchers at the Spanish National Cancer Research Center (CNIO) and the University of Copenhagen have determined the structure of the RAF1 protein, a therapeutic target against cancers associated with KRAS oncogenes that when mutated have the potential to cause normal cells to become cancerous. Read More
Inhibiting metabolic enzyme kills melanoma cells, stops tumor growth
September 1, 2022 -- Researchers at Sanford Burnham Prebys have shown that inhibiting glutaryl-CoA dehydrogenase, an enzyme that plays a significant role in metabolizing the amino acids lysine and tryptophan, selectively kills melanoma cells and stops tumor growth. Read More
Scientific breakthrough from Washington University could treat kidney disease
September 1, 2022 -- Washington University researchers have discovered how to culture podocyte kidney cells outside of the body, which was previously not possible, and the innovation could lead to a treatment for chronic kidney disease. Read More
NIH implants 1st U.S. patient with stem cells to treat AMD
September 1, 2022 -- A National Institutes of Health (NIH) surgical team implanted the first U.S. patient with a patch of tissue made from stem cells to treat advanced “dry” age-related macular degeneration (AMD). Read More
Scientists find link between chronic pain and lung cancer in mice, offers hope for chronic pain
September 1, 2022 -- A new study points to potential new treatments for chronic pain by targeting the metabolite tetrahydrobiopterin (BH4). The therapeutic pathway could improve chronic pain management and combat the opioid epidemic. Read More
Mice study points to glia cells as potential therapy target for Huntington’s disease
August 31, 2022 -- A mice study by University of Rochester Medical Center researchers has reinforced the potential of targeting glia cells -- important support cells found in the brain -- for the treatment of Huntington’s disease, and possibly outright replacement. Read More
Mayo Clinic, Hibiscus BioVentures, Innoforce partner on cell and gene therapy accelerator
August 31, 2022 -- The Mayo Clinic, Hibiscus BioVentures, and Innoforce have teamed up to advance new cures for serious and complex diseases with cell and gene therapies that address unmet patient needs. Read More
Cell culture, mouse studies offer potential new targets for cancer treatments
August 30, 2022 -- University of Gothenburg scientists have identified a previously unknown mechanism controlling tumor growth in cultured cells and mice, potentially enabling future development of new drugs targeted at a range of cancers. Read More
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